PDB1 (YBR221C)


Gene profile

Gene name: PDB1
Reference locus (S288C): YBR221C
Gene biotype: protein_coding

Description: Pyruvate dehydrogenase e1 component subunit beta, mitochondrial; E1 beta subunit of the pyruvate dehydrogenase (PDH) complex; PDH is an evolutionarily conserved multi-protein complex found in mitochondria

Top 10 interactors (score): PDX1 (0.999); LAT1 (0.999); PDA1 (0.999); LPD1 (0.999); IRC15 (0.998); KGD2 (0.992); ACO1 (0.99); CDC19 (0.986); LSC2 (0.98); LSC1 (0.979); PYC1 (0.978); MAE1 (0.978); PDC1 (0.976); CIT1 (0.975); PYK2 (0.974); KGD1 (0.97); CIT2 (0.967); TKL1 (0.967); FBA1 (0.965); PYC2 (0.962)

Homologues (species, bitscore): PDHB (Homo sapiens, 432.6); Pdhb (Mus musculus, 437.2); pdhb (Danio rerio, 444.1); pdhb (Xenopus tropicalis, 428.3); CG11876 (Drosophila melanogaster, 422.9); pdhb-1 (Caenorhabditis elegans, 449.5); MAB1 (Arabidopsis thaliana, 443.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:649459-650559:- gene-YBR221C_AKU4011 rna-NM_001178569.1_AKU4011 cds-NP_009780.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000066.1:20380-21480:- gene-YBR221C_BG1 rna-NM_001178569.1_BG1 cds-NP_009780.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:650614-651714:- gene-YBR221C_Bruggeman rna-NM_001178569.1_Bruggeman cds-NP_009780.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:653819-654919:- gene-YBR221C_CAT1 rna-NM_001178569.1_CAT1 cds-NP_009780.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:640991-642091:- gene-YBR221C_CBS1585 rna-NM_001178569.1_CBS1585 cds-NP_009780.1_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:647416-648516:- gene-YBR221C_CBS436 rna-NM_001178569.1_CBS436 cds-NP_009780.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:735968-737068:- gene-YBR221C_CBS6412 rna-NM_001178569.1_CBS6412 cds-NP_009780.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:647029-648129:- gene-YBR221C_CBS6413 rna-NM_001178569.1_CBS6413 cds-NP_009780.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:658933-660033:- gene-YBR221C_CENPK1137D rna-NM_001178569.1_CENPK1137D cds-NP_009780.1_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:772704-773804:- gene-YBR221C_EthanolRed rna-NM_001178569.1_EthanolRed cds-NP_009780.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:665811-666911:- gene-YBR221C_FaliES1 rna-NM_001178569.1_FaliES1 cds-NP_009780.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000067.1:135444-136544:+ gene-YBR221C_JAY291 rna-NM_001178569.1_JAY291 cds-NP_009780.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:652627-653727:- gene-YBR221C_MUCL30387 rna-NM_001178569.1_MUCL30387 cds-NP_009780.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:669707-670807:- gene-YBR221C_MUCL30388 rna-NM_001178569.1_MUCL30388 cds-NP_009780.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:639343-640443:- gene-YBR221C_MUCL39482 rna-NM_001178569.1_MUCL39482 cds-NP_009780.1_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:649186-650286:- gene-YBR221C_MUCL42920 rna-NM_001178569.1_MUCL42920 cds-NP_009780.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:664950-666050:- gene-YBR221C_NCIM3186 rna-NM_001178569.1_NCIM3186 cds-NP_009780.1_NCIM3186 99.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:641205-642305:- gene-YBR221C_NCYC1407 rna-NM_001178569.1_NCYC1407 cds-NP_009780.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:664321-665421:- gene-YBR221C_PE2H3 rna-NM_001178569.1_PE2H3 cds-NP_009780.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:661997-663097:- gene-YBR221C_PE2H4 rna-NM_001178569.1_PE2H4 cds-NP_009780.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:665153-666253:- gene-YBR221C_S288C rna-NM_001178569.1_S288C cds-NP_009780.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000019.1:20278-21378:- gene-YBR221C_SA1 rna-NM_001178569.1_SA1 cds-NP_009780.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:664821-665921:- gene-YBR221C_ThermosaccDry rna-NM_001178569.1_ThermosaccDry cds-NP_009780.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:644994-646094:- gene-YBR221C_VR1 rna-NM_001178569.1_VR1 cds-NP_009780.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:637686-638786:- gene-YBR221C_ZTW1 rna-NM_001178569.1_ZTW1 cds-NP_009780.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:681663-682760:- gene-YBR221C_Sparadoxus rna-NM_001178569.1_Sparadoxus cds-NP_009780.1_Sparadoxus 93.0 99.7 Verified 1 1 1 False True False False False

Additional files