Gene name: PCT1
Reference locus (S288C): YGR202C
Gene biotype: protein_coding
Description: Cholinephosphate cytidylyltransferase; a rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding; contains an element within the regulatory domain involved in both silencing and activation of enzymatic activity
Top 10 interactors (score): CPT1 (0.996); CKI1 (0.992); EPT1 (0.991); OPI3 (0.952); SCS2 (0.938); PSD1 (0.935); SEC14 (0.934); TAM41 (0.91); SCS22 (0.909); CCT8 (0.901); EKI1 (0.9); CHO2 (0.875); SRP1 (0.867); SPO14 (0.862); INO1 (0.854); PAH1 (0.822); PIS1 (0.82); PSD2 (0.814); CDS1 (0.809); PGS1 (0.776)
Homologues (species, bitscore): PCYT1A (Homo sapiens, 242.7); Pcyt1b (Mus musculus, 240.7); pcyt1aa (Danio rerio, 242.3); pcyt1b (Xenopus tropicalis, 241.5); Cct1 (Drosophila melanogaster, 225.3); pcyt-1 (Caenorhabditis elegans, 207.2); CCT1 (Arabidopsis thaliana, 226.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:868998-870272:- | gene-YGR202C_AKU4011 | rna-NM_001181331.1_AKU4011 | cds-NP_011718.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:149412-150686:- | gene-YGR202C_BG1 | rna-NM_001181331.1_BG1 | cds-NP_011718.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:877200-878474:- | gene-YGR202C_Bruggeman | rna-NM_001181331.1_Bruggeman | cds-NP_011718.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:875196-876470:- | gene-YGR202C_CAT1 | rna-NM_001181331.1_CAT1 | cds-NP_011718.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:872438-873712:- | gene-YGR202C_CBS1585 | rna-NM_001181331.1_CBS1585 | cds-NP_011718.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:875794-877068:- | gene-YGR202C_CBS436 | rna-NM_001181331.1_CBS436 | cds-NP_011718.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:863309-864583:- | gene-YGR202C_CBS6412 | rna-NM_001181331.1_CBS6412 | cds-NP_011718.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:869367-870641:- | gene-YGR202C_CBS6413 | rna-NM_001181331.1_CBS6413 | cds-NP_011718.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:903200-904474:- | gene-YGR202C_CENPK1137D | rna-NM_001181331.1_CENPK1137D | cds-NP_011718.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:857818-859092:- | gene-YGR202C_EthanolRed | rna-NM_001181331.1_EthanolRed | cds-NP_011718.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:862209-863483:- | gene-YGR202C_FaliES1 | rna-NM_001181331.1_FaliES1 | cds-NP_011718.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000148.1:19939-21213:- | gene-YGR202C_JAY291 | rna-NM_001181331.1_JAY291 | cds-NP_011718.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:874685-875959:- | gene-YGR202C_MUCL30387 | rna-NM_001181331.1_MUCL30387 | cds-NP_011718.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:874369-875643:- | gene-YGR202C_MUCL30388 | rna-NM_001181331.1_MUCL30388 | cds-NP_011718.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:867512-868786:- | gene-YGR202C_MUCL39482 | rna-NM_001181331.1_MUCL39482 | cds-NP_011718.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:885063-886337:- | gene-YGR202C_MUCL42920 | rna-NM_001181331.1_MUCL42920 | cds-NP_011718.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:903474-904748:- | gene-YGR202C_NCIM3186 | rna-NM_001181331.1_NCIM3186 | cds-NP_011718.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:863170-864444:- | gene-YGR202C_NCYC1407 | rna-NM_001181331.1_NCYC1407 | cds-NP_011718.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:887780-889054:- | gene-YGR202C_PE2H3 | rna-NM_001181331.1_PE2H3 | cds-NP_011718.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:892890-894164:- | gene-YGR202C_PE2H4 | rna-NM_001181331.1_PE2H4 | cds-NP_011718.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:903474-904748:- | gene-YGR202C_S288C | rna-NM_001181331.1_S288C | cds-NP_011718.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000101.1:24931-26205:- | gene-YGR202C_SA1 | rna-NM_001181331.1_SA1 | cds-NP_011718.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:882720-883994:- | gene-YGR202C_ThermosaccDry | rna-NM_001181331.1_ThermosaccDry | cds-NP_011718.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:987208-988482:- | gene-YGR202C_VR1 | rna-NM_001181331.1_VR1 | cds-NP_011718.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:184167-185441:- | gene-YGR202C_ZTW1 | rna-NM_001181331.1_ZTW1 | cds-NP_011718.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:874689-875981:- | gene-YGR202C_Sparadoxus | rna-NM_001181331.1_Sparadoxus | cds-NP_011718.1_Sparadoxus | 89.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |