PCS60 (YBR222C)


Gene profile

Gene name: PCS60
Reference locus (S288C): YBR222C
Gene biotype: protein_coding

Description: Oxalyl-CoA synthetase; capable of catalyzing conversion of oxalate to oxalyl-CoA; catalyzes first step in pathway of oxalate degradation that functions to protect yeast from inhibitory effects of oxalate; peroxisomal protein that binds mRNA; localizes to both peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid; similar to E. coli long chain acyl-CoA synthetase; Belongs to the ATP-dependent AMP-binding enzyme family

Top 10 interactors (score): PXP1 (0.964); POT1 (0.933); POX1 (0.896); FAA2 (0.89); PEX5 (0.85); PEX3 (0.82); PCD1 (0.784); DCI1 (0.766); PEX6 (0.758); PEX14 (0.748); NPY1 (0.747); TES1 (0.716); PEX11 (0.712); FOX2 (0.674); MDH3 (0.651); ECI1 (0.63); PRE7 (0.613); PRD1 (0.606); PXA1 (0.603); ACP1 (0.603)

Homologues (species, bitscore): ACSF3 (Homo sapiens, 169.1); Acsf3 (Mus musculus, 161.8); LOC562292 (Danio rerio, 163.7); acsf2 (Xenopus tropicalis, 151.0); pdgy (Drosophila melanogaster, 189.5); acs-21 (Caenorhabditis elegans, 166.0); AAE3 (Arabidopsis thaliana, 403.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:651026-652657:- gene-YBR222C_AKU4011 rna-NM_001178570.3_AKU4011 cds-NP_009781.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000066.1:21947-23578:- gene-YBR222C_BG1 rna-NM_001178570.3_BG1 cds-NP_009781.3_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:652181-653812:- gene-YBR222C_Bruggeman rna-NM_001178570.3_Bruggeman cds-NP_009781.3_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:655386-657017:- gene-YBR222C_CAT1 rna-NM_001178570.3_CAT1 cds-NP_009781.3_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:642558-644189:- gene-YBR222C_CBS1585 rna-NM_001178570.3_CBS1585 cds-NP_009781.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:648983-650614:- gene-YBR222C_CBS436 rna-NM_001178570.3_CBS436 cds-NP_009781.3_CBS436 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:737535-739166:- gene-YBR222C_CBS6412 rna-NM_001178570.3_CBS6412 cds-NP_009781.3_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:648596-650227:- gene-YBR222C_CBS6413 rna-NM_001178570.3_CBS6413 cds-NP_009781.3_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:660500-662131:- gene-YBR222C_CENPK1137D rna-NM_001178570.3_CENPK1137D cds-NP_009781.3_CENPK1137D 99.6 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:774271-775902:- gene-YBR222C_EthanolRed rna-NM_001178570.3_EthanolRed cds-NP_009781.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:667378-669009:- gene-YBR222C_FaliES1 rna-NM_001178570.3_FaliES1 cds-NP_009781.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000067.1:133346-134977:+ gene-YBR222C_JAY291 rna-NM_001178570.3_JAY291 cds-NP_009781.3_JAY291 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:654194-655825:- gene-YBR222C_MUCL30387 rna-NM_001178570.3_MUCL30387 cds-NP_009781.3_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:671274-672905:- gene-YBR222C_MUCL30388 rna-NM_001178570.3_MUCL30388 cds-NP_009781.3_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:640910-642541:- gene-YBR222C_MUCL39482 rna-NM_001178570.3_MUCL39482 cds-NP_009781.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:650753-652384:- gene-YBR222C_MUCL42920 rna-NM_001178570.3_MUCL42920 cds-NP_009781.3_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:666517-668148:- gene-YBR222C_NCIM3186 rna-NM_001178570.3_NCIM3186 cds-NP_009781.3_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:642772-644403:- gene-YBR222C_NCYC1407 rna-NM_001178570.3_NCYC1407 cds-NP_009781.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:665888-667519:- gene-YBR222C_PE2H3 rna-NM_001178570.3_PE2H3 cds-NP_009781.3_PE2H3 99.6 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:663564-665195:- gene-YBR222C_PE2H4 rna-NM_001178570.3_PE2H4 cds-NP_009781.3_PE2H4 99.6 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:666720-668351:- gene-YBR222C_S288C rna-NM_001178570.3_S288C cds-NP_009781.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000019.1:21845-23476:- gene-YBR222C_SA1 rna-NM_001178570.3_SA1 cds-NP_009781.3_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:666388-668019:- gene-YBR222C_ThermosaccDry rna-NM_001178570.3_ThermosaccDry cds-NP_009781.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:646561-648192:- gene-YBR222C_VR1 rna-NM_001178570.3_VR1 cds-NP_009781.3_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:639253-640884:- gene-YBR222C_ZTW1 rna-NM_001178570.3_ZTW1 cds-NP_009781.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:683224-684855:- gene-YBR222C_Sparadoxus rna-NM_001178570.3_Sparadoxus cds-NP_009781.3_Sparadoxus 91.0 100.0 Verified 1 1 1 False True False False False

Additional files