Gene name: PCP1
Reference locus (S288C): YGR101W
Gene biotype: protein_coding
Description: Rhomboid protein 1, mitochondrial; Mitochondrial serine protease; required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology; belongs to the rhomboid-GlpG superfamily of intramembrane peptidases
Top 10 interactors (score): RBD2 (0.982); MGM1 (0.977); FZO1 (0.94); CCP1 (0.923); OMA1 (0.92); TUF1 (0.918); YME1 (0.906); AFG3 (0.904); DNM1 (0.896); PAM18 (0.895); MRPS5 (0.895); MEF1 (0.887); MRPL11 (0.878); YML6 (0.875); YTA12 (0.875); MRPL4 (0.851); UGO1 (0.847); TIM50 (0.846); PDA1 (0.839); OXA1 (0.834)
Homologues (species, bitscore): PARL (Homo sapiens, 99.8); Parl (Mus musculus, 99.4); parla (Danio rerio, 107.8); PARL (Xenopus tropicalis, 77.0); rho-7 (Drosophila melanogaster, 79.7); rom-5 (Caenorhabditis elegans, 84.7); RBL12 (Arabidopsis thaliana, 70.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:677543-678583:+ | gene-YGR101W_AKU4011 | rna-NM_001181230.1_AKU4011 | cds-NP_011615.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:113404-114444:+ | gene-YGR101W_BG1 | rna-NM_001181230.1_BG1 | cds-NP_011615.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:679735-680775:+ | gene-YGR101W_Bruggeman | rna-NM_001181230.1_Bruggeman | cds-NP_011615.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:677924-678964:+ | gene-YGR101W_CAT1 | rna-NM_001181230.1_CAT1 | cds-NP_011615.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:678506-679546:+ | gene-YGR101W_CBS1585 | rna-NM_001181230.1_CBS1585 | cds-NP_011615.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:680166-681206:+ | gene-YGR101W_CBS436 | rna-NM_001181230.1_CBS436 | cds-NP_011615.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:670210-671250:+ | gene-YGR101W_CBS6412 | rna-NM_001181230.1_CBS6412 | cds-NP_011615.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:675143-676183:+ | gene-YGR101W_CBS6413 | rna-NM_001181230.1_CBS6413 | cds-NP_011615.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:693036-694076:+ | gene-YGR101W_CENPK1137D | rna-NM_001181230.1_CENPK1137D | cds-NP_011615.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:665133-666173:+ | gene-YGR101W_EthanolRed | rna-NM_001181230.1_EthanolRed | cds-NP_011615.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:668941-669981:+ | gene-YGR101W_FaliES1 | rna-NM_001181230.1_FaliES1 | cds-NP_011615.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000396.1:6572-7612:- | gene-YGR101W_JAY291 | rna-NM_001181230.1_JAY291 | cds-NP_011615.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:676724-677764:+ | gene-YGR101W_MUCL30387 | rna-NM_001181230.1_MUCL30387 | cds-NP_011615.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:679535-680575:+ | gene-YGR101W_MUCL30388 | rna-NM_001181230.1_MUCL30388 | cds-NP_011615.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:674237-675277:+ | gene-YGR101W_MUCL39482 | rna-NM_001181230.1_MUCL39482 | cds-NP_011615.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:684547-685587:+ | gene-YGR101W_MUCL42920 | rna-NM_001181230.1_MUCL42920 | cds-NP_011615.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:693363-694403:+ | gene-YGR101W_NCIM3186 | rna-NM_001181230.1_NCIM3186 | cds-NP_011615.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:668926-669966:+ | gene-YGR101W_NCYC1407 | rna-NM_001181230.1_NCYC1407 | cds-NP_011615.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:671614-672654:+ | gene-YGR101W_PE2H3 | rna-NM_001181230.1_PE2H3 | cds-NP_011615.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:676733-677773:+ | gene-YGR101W_PE2H4 | rna-NM_001181230.1_PE2H4 | cds-NP_011615.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:693363-694403:+ | gene-YGR101W_S288C | rna-NM_001181230.1_S288C | cds-NP_011615.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:119972-121012:+ | gene-YGR101W_SA1 | rna-NM_001181230.1_SA1 | cds-NP_011615.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:689310-690350:+ | gene-YGR101W_ThermosaccDry | rna-NM_001181230.1_ThermosaccDry | cds-NP_011615.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:785802-786842:+ | gene-YGR101W_VR1 | rna-NM_001181230.1_VR1 | cds-NP_011615.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:143558-144598:+ | gene-YGR101W_ZTW1 | rna-NM_001181230.1_ZTW1 | cds-NP_011615.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:679326-680366:+ | gene-YGR101W_Sparadoxus | rna-NM_001181230.1_Sparadoxus | cds-NP_011615.1_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |