PCD1 (YLR151C)


Gene profile

Gene name: PCD1
Reference locus (S288C): YLR151C
Gene biotype: protein_coding

Description: Peroxisomal coenzyme A diphosphatase 1, peroxisomal; 8-oxo-dGTP diphosphatase; prevents spontaneous mutagenesis via sanitization of oxidized purine nucleoside triphosphates; can also act as peroxisomal pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids; nudix hydrolase family member; similar E. coli MutT and human, rat and mouse MTH1

Top 10 interactors (score): MAS2 (0.962); NPY1 (0.96); POX1 (0.938); TES1 (0.937); YSA1 (0.936); FOX2 (0.933); CAT2 (0.911); SPS19 (0.911); FMS1 (0.905); CTT1 (0.904); FAT1 (0.903); PXP1 (0.903); STE23 (0.902); NCP1 (0.9); IDP2 (0.9); DDP1 (0.86); PCS60 (0.784); YLR149C (0.77); YLR152C (0.766); YJR142W (0.745)

Homologues (species, bitscore): NUDT7 (Homo sapiens, 57.0); Nudt7 (Mus musculus, 51.6); NUDT7 (Danio rerio, 60.8); CG11095 (Drosophila melanogaster, 58.5); ndx-3 (Caenorhabditis elegans, 50.4); NUDX15 (Arabidopsis thaliana, 87.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:424195-425217:- gene-YLR151C_AKU4011 rna-NM_001182038.1_AKU4011 cds-NP_013252.1_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:387966-388988:- gene-YLR151C_BG1 rna-NM_001182038.1_BG1 cds-NP_013252.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:436091-437113:- gene-YLR151C_Bruggeman rna-NM_001182038.1_Bruggeman cds-NP_013252.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:435475-436497:- gene-YLR151C_CAT1 rna-NM_001182038.1_CAT1 cds-NP_013252.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:431338-432360:- gene-YLR151C_CBS1585 rna-NM_001182038.1_CBS1585 cds-NP_013252.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:421576-422598:- gene-YLR151C_CBS436 rna-NM_001182038.1_CBS436 cds-NP_013252.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:429756-430778:- gene-YLR151C_CBS6412 rna-NM_001182038.1_CBS6412 cds-NP_013252.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:431603-432625:- gene-YLR151C_CBS6413 rna-NM_001182038.1_CBS6413 cds-NP_013252.1_CBS6413 99.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:426733-427755:- gene-YLR151C_CENPK1137D rna-NM_001182038.1_CENPK1137D cds-NP_013252.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:424396-425418:- gene-YLR151C_EthanolRed rna-NM_001182038.1_EthanolRed cds-NP_013252.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:423907-424929:- gene-YLR151C_FaliES1 rna-NM_001182038.1_FaliES1 cds-NP_013252.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000061.1:30566-31588:- gene-YLR151C_JAY291 rna-NM_001182038.1_JAY291 cds-NP_013252.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:436096-437118:- gene-YLR151C_MUCL30387 rna-NM_001182038.1_MUCL30387 cds-NP_013252.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:440897-441919:- gene-YLR151C_MUCL30388 rna-NM_001182038.1_MUCL30388 cds-NP_013252.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:431847-432869:- gene-YLR151C_MUCL39482 rna-NM_001182038.1_MUCL39482 cds-NP_013252.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:432001-433023:- gene-YLR151C_MUCL42920 rna-NM_001182038.1_MUCL42920 cds-NP_013252.1_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:441689-442711:- gene-YLR151C_NCIM3186 rna-NM_001182038.1_NCIM3186 cds-NP_013252.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:424119-425141:- gene-YLR151C_NCYC1407 rna-NM_001182038.1_NCYC1407 cds-NP_013252.1_NCYC1407 99.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:429677-430699:- gene-YLR151C_PE2H3 rna-NM_001182038.1_PE2H3 cds-NP_013252.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:429418-430440:- gene-YLR151C_PE2H4 rna-NM_001182038.1_PE2H4 cds-NP_013252.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:441715-442737:- gene-YLR151C_S288C rna-NM_001182038.1_S288C cds-NP_013252.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000055.1:67613-68635:- gene-YLR151C_SA1 rna-NM_001182038.1_SA1 cds-NP_013252.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:425117-426139:- gene-YLR151C_ThermosaccDry rna-NM_001182038.1_ThermosaccDry cds-NP_013252.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:437815-438837:- gene-YLR151C_VR1 rna-NM_001182038.1_VR1 cds-NP_013252.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:422903-423925:- gene-YLR151C_ZTW1 rna-NM_001182038.1_ZTW1 cds-NP_013252.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:433083-434105:- gene-YLR151C_Sparadoxus rna-NM_001182038.1_Sparadoxus cds-NP_013252.1_Sparadoxus 89.6 99.9 Unannotated 1 1 0 False False False False True

Additional files