Gene name: PBS2
Reference locus (S288C): YJL128C
Gene biotype: protein_coding
Description: MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily
Top 10 interactors (score): SHO1 (0.999); HOG1 (0.999); SSK2 (0.999); SSK22 (0.997); SSK1 (0.997); STE11 (0.995); YPD1 (0.995); PTC1 (0.994); PTP3 (0.992); NBP2 (0.99); SLT2 (0.983); MIH1 (0.982); SLN1 (0.973); KSS1 (0.959); FUS3 (0.958); SMK1 (0.955); CDC42 (0.953); PTP2 (0.948); SKO1 (0.93); MSS4 (0.929)
Homologues (species, bitscore): MAP2K2 (Homo sapiens, 258.8); Map2k2 (Mus musculus, 259.2); map2k2b (Danio rerio, 255.4); map2k1 (Xenopus tropicalis, 258.8); Dsor1 (Drosophila melanogaster, 266.9); mek-2 (Caenorhabditis elegans, 244.2); MKK2 (Arabidopsis thaliana, 209.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:166405-168411:- | gene-YJL128C_AKU4011 | rna-NM_001181561.2_AKU4011 | cds-NP_012407.2_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:445320-447326:+ | gene-YJL128C_BG1 | rna-NM_001181561.2_BG1 | cds-NP_012407.2_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:178455-180461:- | gene-YJL128C_Bruggeman | rna-NM_001181561.2_Bruggeman | cds-NP_012407.2_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:182264-184270:- | gene-YJL128C_CAT1 | rna-NM_001181561.2_CAT1 | cds-NP_012407.2_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:172039-174045:- | gene-YJL128C_CBS1585 | rna-NM_001181561.2_CBS1585 | cds-NP_012407.2_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:196781-198787:- | gene-YJL128C_CBS436 | rna-NM_001181561.2_CBS436 | cds-NP_012407.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:168056-170062:- | gene-YJL128C_CBS6412 | rna-NM_001181561.2_CBS6412 | cds-NP_012407.2_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:169514-171520:- | gene-YJL128C_CBS6413 | rna-NM_001181561.2_CBS6413 | cds-NP_012407.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:160564-162570:- | gene-YJL128C_CENPK1137D | rna-NM_001181561.2_CENPK1137D | cds-NP_012407.2_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:170373-172379:- | gene-YJL128C_EthanolRed | rna-NM_001181561.2_EthanolRed | cds-NP_012407.2_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:176025-178031:- | gene-YJL128C_FaliES1 | rna-NM_001181561.2_FaliES1 | cds-NP_012407.2_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000099.1:57202-59208:- | gene-YJL128C_JAY291 | rna-NM_001181561.2_JAY291 | cds-NP_012407.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:180723-182729:- | gene-YJL128C_MUCL30387 | rna-NM_001181561.2_MUCL30387 | cds-NP_012407.2_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:176800-178806:- | gene-YJL128C_MUCL30388 | rna-NM_001181561.2_MUCL30388 | cds-NP_012407.2_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:170985-172991:- | gene-YJL128C_MUCL39482 | rna-NM_001181561.2_MUCL39482 | cds-NP_012407.2_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:176788-178794:- | gene-YJL128C_MUCL42920 | rna-NM_001181561.2_MUCL42920 | cds-NP_012407.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:178076-180082:- | gene-YJL128C_NCIM3186 | rna-NM_001181561.2_NCIM3186 | cds-NP_012407.2_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:169392-171398:- | gene-YJL128C_NCYC1407 | rna-NM_001181561.2_NCYC1407 | cds-NP_012407.2_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:182183-184189:- | gene-YJL128C_PE2H3 | rna-NM_001181561.2_PE2H3 | cds-NP_012407.2_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:181827-183833:- | gene-YJL128C_PE2H4 | rna-NM_001181561.2_PE2H4 | cds-NP_012407.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:178097-180103:- | gene-YJL128C_S288C | rna-NM_001181561.2_S288C | cds-NP_012407.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000085.1:19067-21073:+ | gene-YJL128C_SA1 | rna-NM_001181561.2_SA1 | cds-NP_012407.2_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:169216-171222:- | gene-YJL128C_ThermosaccDry | rna-NM_001181561.2_ThermosaccDry | cds-NP_012407.2_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:176300-178306:- | gene-YJL128C_VR1 | rna-NM_001181561.2_VR1 | cds-NP_012407.2_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:156507-158513:- | gene-YJL128C_ZTW1 | rna-NM_001181561.2_ZTW1 | cds-NP_012407.2_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:181704-183710:- | gene-YJL128C_Sparadoxus | rna-NM_001181561.2_Sparadoxus | cds-NP_012407.2_Sparadoxus | 91.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |