Gene name: PBP1
Reference locus (S288C): YGR178C
Gene biotype: protein_coding
Description: PAB1-binding protein 1; Component of glucose deprivation induced stress granules; involved in P-body-dependent granule assembly; similar to human ataxin-2; interacts with Pab1p to regulate mRNA polyadenylation; interacts with Mkt1p to regulate HO translation; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress
Top 10 interactors (score): DHH1 (0.999); PAB1 (0.999); LSM12 (0.999); PES4 (0.984); MIP6 (0.984); MKT1 (0.983); PBP4 (0.979); SCD6 (0.914); DCP1 (0.887); TIF4632 (0.881); TIF4631 (0.878); DCP2 (0.838); PUB1 (0.837); EDC3 (0.834); CDC39 (0.817); BRE5 (0.812); RIE1 (0.786); LSM1 (0.772); XRN1 (0.764); MLP2 (0.757)
Homologues (species, bitscore): ATXN2L (Homo sapiens, 67.0); Atxn2l (Mus musculus, 67.4); atxn2 (Danio rerio, 77.8); atxn2l (Xenopus tropicalis, 58.5); Atx2 (Drosophila melanogaster, 58.5); CID4 (Arabidopsis thaliana, 107.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:818800-820968:- | gene-YGR178C_AKU4011 | rna-NM_001181307.3_AKU4011 | cds-NP_011694.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:96912-99080:- | gene-YGR178C_BG1 | rna-NM_001181307.3_BG1 | cds-NP_011694.3_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:824728-826896:- | gene-YGR178C_Bruggeman | rna-NM_001181307.3_Bruggeman | cds-NP_011694.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:820825-822993:- | gene-YGR178C_CAT1 | rna-NM_001181307.3_CAT1 | cds-NP_011694.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:819515-821683:- | gene-YGR178C_CBS1585 | rna-NM_001181307.3_CBS1585 | cds-NP_011694.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:823406-825574:- | gene-YGR178C_CBS436 | rna-NM_001181307.3_CBS436 | cds-NP_011694.3_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:810885-813053:- | gene-YGR178C_CBS6412 | rna-NM_001181307.3_CBS6412 | cds-NP_011694.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:816381-818549:- | gene-YGR178C_CBS6413 | rna-NM_001181307.3_CBS6413 | cds-NP_011694.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:850776-852944:- | gene-YGR178C_CENPK1137D | rna-NM_001181307.3_CENPK1137D | cds-NP_011694.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:805391-807559:- | gene-YGR178C_EthanolRed | rna-NM_001181307.3_EthanolRed | cds-NP_011694.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:809782-811950:- | gene-YGR178C_FaliES1 | rna-NM_001181307.3_FaliES1 | cds-NP_011694.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000226.1:4191-6359:+ | gene-YGR178C_JAY291 | rna-NM_001181307.3_JAY291 | cds-NP_011694.3_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:822218-824386:- | gene-YGR178C_MUCL30387 | rna-NM_001181307.3_MUCL30387 | cds-NP_011694.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:821929-824097:- | gene-YGR178C_MUCL30388 | rna-NM_001181307.3_MUCL30388 | cds-NP_011694.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:815091-817259:- | gene-YGR178C_MUCL39482 | rna-NM_001181307.3_MUCL39482 | cds-NP_011694.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:831706-833874:- | gene-YGR178C_MUCL42920 | rna-NM_001181307.3_MUCL42920 | cds-NP_011694.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:851047-853215:- | gene-YGR178C_NCIM3186 | rna-NM_001181307.3_NCIM3186 | cds-NP_011694.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:810200-812368:- | gene-YGR178C_NCYC1407 | rna-NM_001181307.3_NCYC1407 | cds-NP_011694.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:829396-831564:- | gene-YGR178C_PE2H3 | rna-NM_001181307.3_PE2H3 | cds-NP_011694.3_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:834506-836674:- | gene-YGR178C_PE2H4 | rna-NM_001181307.3_PE2H4 | cds-NP_011694.3_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:851047-853215:- | gene-YGR178C_S288C | rna-NM_001181307.3_S288C | cds-NP_011694.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000035.1:74765-76933:- | gene-YGR178C_SA1 | rna-NM_001181307.3_SA1 | cds-NP_011694.3_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:830293-832461:- | gene-YGR178C_ThermosaccDry | rna-NM_001181307.3_ThermosaccDry | cds-NP_011694.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:934541-936709:- | gene-YGR178C_VR1 | rna-NM_001181307.3_VR1 | cds-NP_011694.3_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:131731-133899:- | gene-YGR178C_ZTW1 | rna-NM_001181307.3_ZTW1 | cds-NP_011694.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:821472-823640:- | gene-YGR178C_Sparadoxus | rna-NM_001181307.3_Sparadoxus | cds-NP_011694.3_Sparadoxus | 90.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |