Gene name: PBI2
Reference locus (S288C): YNL015W
Gene biotype: protein_coding
Description: Cytosolic inhibitor of vacuolar proteinase B (PRB1); required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion; protein abundance increases in response to DNA replication stress; Belongs to the protease inhibitor I9 family
Top 10 interactors (score): STF2 (0.936); YHR138C (0.881); PRB1 (0.859); SEC18 (0.811); PAI3 (0.79); TFS1 (0.786); STF1 (0.772); SEC17 (0.761); SOF1 (0.685); RPF1 (0.685); YTM1 (0.677); GPG1 (0.624); HOR7 (0.603); NYV1 (0.6); YPT7 (0.588); PEP4 (0.579); DDR2 (0.562); SOD2 (0.546); OM14 (0.543); PGM2 (0.511)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:588347-588574:+ | gene-YNL015W_AKU4011 | rna-NM_001182854.1_AKU4011 | cds-NP_014383.1_AKU4011 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:490819-491046:+ | gene-YNL015W_BG1 | rna-NM_001182854.1_BG1 | cds-NP_014383.1_BG1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:605274-605501:+ | gene-YNL015W_Bruggeman | rna-NM_001182854.1_Bruggeman | cds-NP_014383.1_Bruggeman | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:640644-640871:+ | gene-YNL015W_CAT1 | rna-NM_001182854.1_CAT1 | cds-NP_014383.1_CAT1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:594033-594260:+ | gene-YNL015W_CBS1585 | rna-NM_001182854.1_CBS1585 | cds-NP_014383.1_CBS1585 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:656144-656371:+ | gene-YNL015W_CBS436 | rna-NM_001182854.1_CBS436 | cds-NP_014383.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:583837-584064:+ | gene-YNL015W_CBS6412 | rna-NM_001182854.1_CBS6412 | cds-NP_014383.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:585056-585283:+ | gene-YNL015W_CBS6413 | rna-NM_001182854.1_CBS6413 | cds-NP_014383.1_CBS6413 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:599033-599260:+ | gene-YNL015W_CENPK1137D | rna-NM_001182854.1_CENPK1137D | cds-NP_014383.1_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:590456-590683:+ | gene-YNL015W_EthanolRed | rna-NM_001182854.1_EthanolRed | cds-NP_014383.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:581227-581454:+ | gene-YNL015W_FaliES1 | rna-NM_001182854.1_FaliES1 | cds-NP_014383.1_FaliES1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000008.1:26503-26730:- | gene-YNL015W_JAY291 | rna-NM_001182854.1_JAY291 | cds-NP_014383.1_JAY291 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:603363-603590:+ | gene-YNL015W_MUCL30387 | rna-NM_001182854.1_MUCL30387 | cds-NP_014383.1_MUCL30387 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:605193-605420:- | gene-YNL015W_MUCL30388 | rna-NM_001182854.1_MUCL30388 | cds-NP_014383.1_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:585588-585815:+ | gene-YNL015W_MUCL39482 | rna-NM_001182854.1_MUCL39482 | cds-NP_014383.1_MUCL39482 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:589457-589684:+ | gene-YNL015W_MUCL42920 | rna-NM_001182854.1_MUCL42920 | cds-NP_014383.1_MUCL42920 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:605353-605580:+ | gene-YNL015W_NCIM3186 | rna-NM_001182854.1_NCIM3186 | cds-NP_014383.1_NCIM3186 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:587833-588060:+ | gene-YNL015W_NCYC1407 | rna-NM_001182854.1_NCYC1407 | cds-NP_014383.1_NCYC1407 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:589843-590070:+ | gene-YNL015W_PE2H3 | rna-NM_001182854.1_PE2H3 | cds-NP_014383.1_PE2H3 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:591161-591388:+ | gene-YNL015W_PE2H4 | rna-NM_001182854.1_PE2H4 | cds-NP_014383.1_PE2H4 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:605384-605611:+ | gene-YNL015W_S288C | rna-NM_001182854.1_S288C | cds-NP_014383.1_S288C | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000068.1:3058-3285:+ | gene-YNL015W_SA1 | rna-NM_001182854.1_SA1 | cds-NP_014383.1_SA1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:581569-581796:+ | gene-YNL015W_ThermosaccDry | rna-NM_001182854.1_ThermosaccDry | cds-NP_014383.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:624188-624415:+ | gene-YNL015W_VR1 | rna-NM_001182854.1_VR1 | cds-NP_014383.1_VR1 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:490453-490680:+ | gene-YNL015W_ZTW1 | rna-NM_001182854.1_ZTW1 | cds-NP_014383.1_ZTW1 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:596683-596910:+ | gene-YNL015W_Sparadoxus | rna-NM_001182854.1_Sparadoxus | cds-NP_014383.1_Sparadoxus | 93.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |