Gene name: PAT1
Reference locus (S288C): YCR077C
Gene biotype: protein_coding
Description: DNA topoisomerase 2-associated protein PAT1; Deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; associated with topoisomerase II; binds to mRNAs under glucose starvation, most often in the 3' UTR; functionally linked to Pab1p; forms cytoplasmic foci upon DNA replication stress; phosphorylation by PKA inhibits P body foci formation; Belongs to the PAT1 family
Top 10 interactors (score): LSM2 (0.999); LSM3 (0.999); LSM7 (0.999); XRN1 (0.999); LSM1 (0.999); LSM5 (0.999); LSM4 (0.999); DHH1 (0.999); LSM6 (0.999); DCP2 (0.999); EDC3 (0.998); DCP1 (0.99); CDC39 (0.969); SCD6 (0.956); YGR054W (0.943); RPS28A (0.927); RPS6B (0.926); RPS28B (0.925); RPS25A (0.917); RPS1B (0.91)
Homologues (species, bitscore): SPEG (Homo sapiens, 53.5); Speg (Mus musculus, 52.0); dp (Drosophila melanogaster, 53.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:244739-247129:- | gene-YCR077C_AKU4011 | rna-NM_001178786.2_AKU4011 | cds-NP_010002.3_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000067.1:103395-105785:- | gene-YCR077C_BG1 | rna-NM_001178786.2_BG1 | cds-NP_010002.3_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:240950-243340:- | gene-YCR077C_Bruggeman | rna-NM_001178786.2_Bruggeman | cds-NP_010002.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:252000-254390:- | gene-YCR077C_CAT1 | rna-NM_001178786.2_CAT1 | cds-NP_010002.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:239554-241944:- | gene-YCR077C_CBS1585 | rna-NM_001178786.2_CBS1585 | cds-NP_010002.3_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:251335-253725:- | gene-YCR077C_CBS436 | rna-NM_001178786.2_CBS436 | cds-NP_010002.3_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:231256-233646:- | gene-YCR077C_CBS6412 | rna-NM_001178786.2_CBS6412 | cds-NP_010002.3_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:245604-247994:- | gene-YCR077C_CBS6413 | rna-NM_001178786.2_CBS6413 | cds-NP_010002.3_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:249452-251827:- | gene-YCR077C_CENPK1137D | rna-NM_001178786.2_CENPK1137D | cds-NP_010002.3_CENPK1137D | 97.7 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:240554-242944:- | gene-YCR077C_EthanolRed | rna-NM_001178786.2_EthanolRed | cds-NP_010002.3_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:245917-248307:- | gene-YCR077C_FaliES1 | rna-NM_001178786.2_FaliES1 | cds-NP_010002.3_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000323.1:40483-42873:+ | gene-YCR077C_JAY291 | rna-NM_001178786.2_JAY291 | cds-NP_010002.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:238079-240469:- | gene-YCR077C_MUCL30387 | rna-NM_001178786.2_MUCL30387 | cds-NP_010002.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:237945-240335:- | gene-YCR077C_MUCL30388 | rna-NM_001178786.2_MUCL30388 | cds-NP_010002.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:246118-248508:- | gene-YCR077C_MUCL39482 | rna-NM_001178786.2_MUCL39482 | cds-NP_010002.3_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:242524-244914:- | gene-YCR077C_MUCL42920 | rna-NM_001178786.2_MUCL42920 | cds-NP_010002.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:249870-252260:- | gene-YCR077C_NCIM3186 | rna-NM_001178786.2_NCIM3186 | cds-NP_010002.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:246948-249347:- | gene-YCR077C_NCYC1407 | rna-NM_001178786.2_NCYC1407 | cds-NP_010002.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:261512-263902:- | gene-YCR077C_PE2H3 | rna-NM_001178786.2_PE2H3 | cds-NP_010002.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:250066-252456:- | gene-YCR077C_PE2H4 | rna-NM_001178786.2_PE2H4 | cds-NP_010002.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:250238-252628:- | gene-YCR077C_S288C | rna-NM_001178786.2_S288C | cds-NP_010002.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000044.1:50087-52477:- | gene-YCR077C_SA1 | rna-NM_001178786.2_SA1 | cds-NP_010002.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:245844-248234:- | gene-YCR077C_ThermosaccDry | rna-NM_001178786.2_ThermosaccDry | cds-NP_010002.3_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:257054-259444:- | gene-YCR077C_VR1 | rna-NM_001178786.2_VR1 | cds-NP_010002.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:243699-246089:- | gene-YCR077C_ZTW1 | rna-NM_001178786.2_ZTW1 | cds-NP_010002.3_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:277848-280229:- | gene-YCR077C_Sparadoxus | rna-NM_001178786.2_Sparadoxus | cds-NP_010002.3_Sparadoxus | 90.9 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |