Gene name: PAP2
Reference locus (S288C): YOL115W
Gene biotype: protein_coding
Description: Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of TRAMP; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; required for mRNA surveillance and maintenance of genome integrity, serving as a link between RNA and DNA metabolism; overlapping but non-redundant functions with Trf5p; relocalizes to cytosol in response to hypoxia
Top 10 interactors (score): AIR1 (0.999); AIR2 (0.999); MTR4 (0.999); RRP6 (0.996); TRF5 (0.989); NRD1 (0.988); PAP1 (0.973); DIS3 (0.932); NAB3 (0.922); CAF40 (0.919); SKI2 (0.914); RRP40 (0.878); TOP1 (0.875); RAT1 (0.847); RRP46 (0.84); PRP43 (0.815); SKI6 (0.814); DHR2 (0.813); XRN1 (0.808); RRP43 (0.798)
Homologues (species, bitscore): PAPD5 (Homo sapiens, 206.8); Papd5 (Mus musculus, 208.8); PAPD5 (Danio rerio, 219.5); papd5 (Xenopus tropicalis, 169.1); Trf4-1 (Drosophila melanogaster, 193.4); gld-4 (Caenorhabditis elegans, 162.5); AT5G53770 (Arabidopsis thaliana, 195.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:90121-91875:+ | gene-YOL115W_AKU4011 | rna-NM_001183369.1_AKU4011 | cds-NP_014526.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:55749-57503:+ | gene-YOL115W_BG1 | rna-NM_001183369.1_BG1 | cds-NP_014526.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:91394-93148:+ | gene-YOL115W_Bruggeman | rna-NM_001183369.1_Bruggeman | cds-NP_014526.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:90584-92338:+ | gene-YOL115W_CAT1 | rna-NM_001183369.1_CAT1 | cds-NP_014526.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:84596-86350:+ | gene-YOL115W_CBS1585 | rna-NM_001183369.1_CBS1585 | cds-NP_014526.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:90431-92185:+ | gene-YOL115W_CBS436 | rna-NM_001183369.1_CBS436 | cds-NP_014526.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:84459-86213:+ | gene-YOL115W_CBS6412 | rna-NM_001183369.1_CBS6412 | cds-NP_014526.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:90927-92681:+ | gene-YOL115W_CBS6413 | rna-NM_001183369.1_CBS6413 | cds-NP_014526.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:101370-103124:+ | gene-YOL115W_CENPK1137D | rna-NM_001183369.1_CENPK1137D | cds-NP_014526.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:88393-90147:+ | gene-YOL115W_EthanolRed | rna-NM_001183369.1_EthanolRed | cds-NP_014526.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:90422-92176:+ | gene-YOL115W_FaliES1 | rna-NM_001183369.1_FaliES1 | cds-NP_014526.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000203.1:7630-9384:+ | gene-YOL115W_JAY291 | rna-NM_001183369.1_JAY291 | cds-NP_014526.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:96036-97790:+ | gene-YOL115W_MUCL30387 | rna-NM_001183369.1_MUCL30387 | cds-NP_014526.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:99035-100789:+ | gene-YOL115W_MUCL30388 | rna-NM_001183369.1_MUCL30388 | cds-NP_014526.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:92534-94288:+ | gene-YOL115W_MUCL39482 | rna-NM_001183369.1_MUCL39482 | cds-NP_014526.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:108665-110419:+ | gene-YOL115W_MUCL42920 | rna-NM_001183369.1_MUCL42920 | cds-NP_014526.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:101364-103118:+ | gene-YOL115W_NCIM3186 | rna-NM_001183369.1_NCIM3186 | cds-NP_014526.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:98569-100323:+ | gene-YOL115W_NCYC1407 | rna-NM_001183369.1_NCYC1407 | cds-NP_014526.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:77030-78784:+ | gene-YOL115W_PE2H3 | rna-NM_001183369.1_PE2H3 | cds-NP_014526.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:93958-95712:+ | gene-YOL115W_PE2H4 | rna-NM_001183369.1_PE2H4 | cds-NP_014526.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:101475-103229:+ | gene-YOL115W_S288C | rna-NM_001183369.1_S288C | cds-NP_014526.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:74902-76656:+ | gene-YOL115W_SA1 | rna-NM_001183369.1_SA1 | cds-NP_014526.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:89560-91314:+ | gene-YOL115W_ThermosaccDry | rna-NM_001183369.1_ThermosaccDry | cds-NP_014526.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:90207-91961:+ | gene-YOL115W_VR1 | rna-NM_001183369.1_VR1 | cds-NP_014526.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:89284-91038:+ | gene-YOL115W_ZTW1 | rna-NM_001183369.1_ZTW1 | cds-NP_014526.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:92065-93822:+ | gene-YOL115W_Sparadoxus | rna-NM_001183369.1_Sparadoxus | cds-NP_014526.1_Sparadoxus | 90.0 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |