Gene name: PAN1
Reference locus (S288C): YIR006C
Gene biotype: protein_coding
Description: Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress; previously thought to be a subunit of poly(A) ribonuclease
Top 10 interactors (score): END3 (0.999); SLA2 (0.998); ENT1 (0.998); LAS17 (0.996); PRK1 (0.996); ARP2 (0.993); YAP1801 (0.993); APL3 (0.989); YAP1802 (0.985); ENT2 (0.985); ABP1 (0.981); CLC1 (0.974); CHC1 (0.974); ARK1 (0.97); ACT1 (0.969); RVS167 (0.969); BZZ1 (0.967); MYO5 (0.962); EDE1 (0.945); MYO3 (0.943)
Homologues (species, bitscore): ITSN1 (Homo sapiens, 82.0); Itsn1 (Mus musculus, 80.5); itsn1 (Danio rerio, 81.3); eps15l1 (Xenopus tropicalis, 74.3); Eps-15 (Drosophila melanogaster, 70.9); ehs-1 (Caenorhabditis elegans, 72.4); AT1G21630 (Arabidopsis thaliana, 62.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:364857-369242:- | gene-YIR006C_AKU4011 | rna-NM_001179528.3_AKU4011 | cds-NP_012271.3_AKU4011 | 98.3 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000072.1:57324-61748:+ | gene-YIR006C_BG1 | rna-NM_001179528.3_BG1 | cds-NP_012271.3_BG1 | 99.5 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:369294-373676:- | gene-YIR006C_Bruggeman | rna-NM_001179528.3_Bruggeman | cds-NP_012271.3_Bruggeman | 98.4 | 98.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:355960-360384:- | gene-YIR006C_CAT1 | rna-NM_001179528.3_CAT1 | cds-NP_012271.3_CAT1 | 99.5 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:364874-369277:- | gene-YIR006C_CBS1585 | rna-NM_001179528.3_CBS1585 | cds-NP_012271.3_CBS1585 | 98.7 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:357526-361950:- | gene-YIR006C_CBS436 | rna-NM_001179528.3_CBS436 | cds-NP_012271.3_CBS436 | 99.4 | 99.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:360377-364762:- | gene-YIR006C_CBS6412 | rna-NM_001179528.3_CBS6412 | cds-NP_012271.3_CBS6412 | 98.3 | 98.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:356954-361357:- | gene-YIR006C_CBS6413 | rna-NM_001179528.3_CBS6413 | cds-NP_012271.3_CBS6413 | 98.6 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:357527-361969:- | gene-YIR006C_CENPK1137D | rna-NM_001179528.3_CENPK1137D | cds-NP_012271.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:347931-352334:- | gene-YIR006C_EthanolRed | rna-NM_001179528.3_EthanolRed | cds-NP_012271.3_EthanolRed | 98.7 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:366174-371061:- | gene-YIR006C_FaliES1 | rna-NM_001179528.3_FaliES1 | cds-NP_012271.3_FaliES1 | 88.8 | 99.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000009.1:20906-25330:+ | gene-YIR006C_JAY291 | rna-NM_001179528.3_JAY291 | cds-NP_012271.3_JAY291 | 99.5 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:366499-370923:- | gene-YIR006C_MUCL30387 | rna-NM_001179528.3_MUCL30387 | cds-NP_012271.3_MUCL30387 | 99.5 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:363244-367686:- | gene-YIR006C_MUCL30388 | rna-NM_001179528.3_MUCL30388 | cds-NP_012271.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:365511-369914:- | gene-YIR006C_MUCL39482 | rna-NM_001179528.3_MUCL39482 | cds-NP_012271.3_MUCL39482 | 98.7 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:369107-373492:- | gene-YIR006C_MUCL42920 | rna-NM_001179528.3_MUCL42920 | cds-NP_012271.3_MUCL42920 | 98.6 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:365466-369908:- | gene-YIR006C_NCIM3186 | rna-NM_001179528.3_NCIM3186 | cds-NP_012271.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:369756-374141:- | gene-YIR006C_NCYC1407 | rna-NM_001179528.3_NCYC1407 | cds-NP_012271.3_NCYC1407 | 98.3 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:359538-363962:- | gene-YIR006C_PE2H3 | rna-NM_001179528.3_PE2H3 | cds-NP_012271.3_PE2H3 | 99.5 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:354244-358668:- | gene-YIR006C_PE2H4 | rna-NM_001179528.3_PE2H4 | cds-NP_012271.3_PE2H4 | 99.5 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:365466-369908:- | gene-YIR006C_S288C | rna-NM_001179528.3_S288C | cds-NP_012271.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000066.1:40320-44747:- | gene-YIR006C_SA1 | rna-NM_001179528.3_SA1 | cds-NP_012271.3_SA1 | 97.6 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:364280-368665:- | gene-YIR006C_ThermosaccDry | rna-NM_001179528.3_ThermosaccDry | cds-NP_012271.3_ThermosaccDry | 98.2 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:360099-364739:- | gene-YIR006C_VR1 | rna-NM_001179528.3_VR1 | cds-NP_012271.3_VR1 | 93.2 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:338276-342661:- | gene-YIR006C_ZTW1 | rna-NM_001179528.3_ZTW1 | cds-NP_012271.3_ZTW1 | 98.3 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:359682-364100:- | gene-YIR006C_Sparadoxus | rna-NM_001179528.3_Sparadoxus | cds-NP_012271.3_Sparadoxus | 86.9 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |