PAM18 (YLR008C)


Gene profile

Gene name: PAM18
Reference locus (S288C): YLR008C
Gene biotype: protein_coding

Description: Subunit of the import motor (PAM complex); the PAM complex is a component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); essential J-protein cochaperone that stimulates Ssc1p ATPase activity to drive import; inhibited by Pam16p

Top 10 interactors (score): PAM16 (0.999); SSC1 (0.999); TIM50 (0.999); TIM17 (0.999); TIM44 (0.999); MGE1 (0.999); TIM21 (0.998); TIM23 (0.998); PAM17 (0.992); JAC1 (0.977); MGR2 (0.975); MAS2 (0.97); TOM22 (0.963); MAS1 (0.96); MDJ1 (0.957); TOM40 (0.941); TIM54 (0.925); TIM9 (0.916); TIM10 (0.911); HSP60 (0.909)

Homologues (species, bitscore): DNAJC19 (Homo sapiens, 84.0); Dnajc15 (Mus musculus, 79.7); dnajc19 (Danio rerio, 88.6); dnajc19 (Xenopus tropicalis, 88.6); CG7394 (Drosophila melanogaster, 90.1); dnj-21 (Caenorhabditis elegans, 82.4); AT2G35795 (Arabidopsis thaliana, 79.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:153558-154064:- gene-YLR008C_AKU4011 rna-NM_001181895.1_AKU4011 cds-NP_013108.1_AKU4011 99.4 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:116765-117271:- gene-YLR008C_BG1 rna-NM_001181895.1_BG1 cds-NP_013108.1_BG1 98.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:163928-164434:- gene-YLR008C_Bruggeman rna-NM_001181895.1_Bruggeman cds-NP_013108.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:164247-164753:- gene-YLR008C_CAT1 rna-NM_001181895.1_CAT1 cds-NP_013108.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:161156-161662:- gene-YLR008C_CBS1585 rna-NM_001181895.1_CBS1585 cds-NP_013108.1_CBS1585 99.4 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:151780-152286:- gene-YLR008C_CBS436 rna-NM_001181895.1_CBS436 cds-NP_013108.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:159927-160433:- gene-YLR008C_CBS6412 rna-NM_001181895.1_CBS6412 cds-NP_013108.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:161423-161929:- gene-YLR008C_CBS6413 rna-NM_001181895.1_CBS6413 cds-NP_013108.1_CBS6413 99.4 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:150839-151345:- gene-YLR008C_CENPK1137D rna-NM_001181895.1_CENPK1137D cds-NP_013108.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:153578-154084:- gene-YLR008C_EthanolRed rna-NM_001181895.1_EthanolRed cds-NP_013108.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:153149-153655:- gene-YLR008C_FaliES1 rna-NM_001181895.1_FaliES1 cds-NP_013108.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000083.1:1941-2447:+ gene-YLR008C_JAY291 rna-NM_001181895.1_JAY291 cds-NP_013108.1_JAY291 98.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:161284-161790:- gene-YLR008C_MUCL30387 rna-NM_001181895.1_MUCL30387 cds-NP_013108.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:166981-167487:- gene-YLR008C_MUCL30388 rna-NM_001181895.1_MUCL30388 cds-NP_013108.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:161628-162134:- gene-YLR008C_MUCL39482 rna-NM_001181895.1_MUCL39482 cds-NP_013108.1_MUCL39482 99.4 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:161553-162059:- gene-YLR008C_MUCL42920 rna-NM_001181895.1_MUCL42920 cds-NP_013108.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:165551-166057:- gene-YLR008C_NCIM3186 rna-NM_001181895.1_NCIM3186 cds-NP_013108.1_NCIM3186 99.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:153231-153737:- gene-YLR008C_NCYC1407 rna-NM_001181895.1_NCYC1407 cds-NP_013108.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:159575-160081:- gene-YLR008C_PE2H3 rna-NM_001181895.1_PE2H3 cds-NP_013108.1_PE2H3 98.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:159316-159822:- gene-YLR008C_PE2H4 rna-NM_001181895.1_PE2H4 cds-NP_013108.1_PE2H4 98.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:165577-166083:- gene-YLR008C_S288C rna-NM_001181895.1_S288C cds-NP_013108.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000062.1:68774-69280:- gene-YLR008C_SA1 rna-NM_001181895.1_SA1 cds-NP_013108.1_SA1 98.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:153652-154158:- gene-YLR008C_ThermosaccDry rna-NM_001181895.1_ThermosaccDry cds-NP_013108.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:167028-167534:- gene-YLR008C_VR1 rna-NM_001181895.1_VR1 cds-NP_013108.1_VR1 98.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:152983-153489:- gene-YLR008C_ZTW1 rna-NM_001181895.1_ZTW1 cds-NP_013108.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:161586-162092:- gene-YLR008C_Sparadoxus rna-NM_001181895.1_Sparadoxus cds-NP_013108.1_Sparadoxus 90.9 100.0 Verified 1 1 1 False True False False False

Additional files