Gene name: PAF1
Reference locus (S288C): YBR279W
Gene biotype: protein_coding
Description: RNA polymerase II-associated protein 1; Component of the Paf1p complex involved in transcription elongation; binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cell cycle-regulated genes; involved in SER3 repression by helping to maintain SRG1 transcription-dependent nucleosome occupancy; homolog of human PD2/hPAF1
Top 10 interactors (score): SPT16 (0.999); CTR9 (0.999); RTF1 (0.999); CDC73 (0.999); LEO1 (0.999); RPO21 (0.996); POB3 (0.995); SPT5 (0.993); RPB7 (0.983); RPB3 (0.952); SKI8 (0.928); SPT6 (0.917); DST1 (0.904); RPB2 (0.898); RPO26 (0.895); SPT4 (0.885); RPB4 (0.885); SLT2 (0.857); RPB9 (0.848); RPB5 (0.846)
Homologues (species, bitscore): PAF1 (Homo sapiens, 54.7); Paf1 (Mus musculus, 53.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:745539-746894:+ | gene-YBR279W_AKU4011 | rna-NM_001178627.1_AKU4011 | cds-NP_009838.1_AKU4011 | 97.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:116552-117889:+ | gene-YBR279W_BG1 | rna-NM_001178627.1_BG1 | cds-NP_009838.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:746691-748028:+ | gene-YBR279W_Bruggeman | rna-NM_001178627.1_Bruggeman | cds-NP_009838.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:750416-751753:+ | gene-YBR279W_CAT1 | rna-NM_001178627.1_CAT1 | cds-NP_009838.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:737105-738460:+ | gene-YBR279W_CBS1585 | rna-NM_001178627.1_CBS1585 | cds-NP_009838.1_CBS1585 | 97.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:743539-744876:+ | gene-YBR279W_CBS436 | rna-NM_001178627.1_CBS436 | cds-NP_009838.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:831720-833075:+ | gene-YBR279W_CBS6412 | rna-NM_001178627.1_CBS6412 | cds-NP_009838.1_CBS6412 | 97.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:743153-744508:+ | gene-YBR279W_CBS6413 | rna-NM_001178627.1_CBS6413 | cds-NP_009838.1_CBS6413 | 97.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:755157-756494:+ | gene-YBR279W_CENPK1137D | rna-NM_001178627.1_CENPK1137D | cds-NP_009838.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:868574-869929:+ | gene-YBR279W_EthanolRed | rna-NM_001178627.1_EthanolRed | cds-NP_009838.1_EthanolRed | 97.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:761921-763276:+ | gene-YBR279W_FaliES1 | rna-NM_001178627.1_FaliES1 | cds-NP_009838.1_FaliES1 | 97.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:40813-42150:- | gene-YBR279W_JAY291 | rna-NM_001178627.1_JAY291 | cds-NP_009838.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:748734-750071:+ | gene-YBR279W_MUCL30387 | rna-NM_001178627.1_MUCL30387 | cds-NP_009838.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:765816-767153:+ | gene-YBR279W_MUCL30388 | rna-NM_001178627.1_MUCL30388 | cds-NP_009838.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:735412-736767:+ | gene-YBR279W_MUCL39482 | rna-NM_001178627.1_MUCL39482 | cds-NP_009838.1_MUCL39482 | 97.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:745278-746615:+ | gene-YBR279W_MUCL42920 | rna-NM_001178627.1_MUCL42920 | cds-NP_009838.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:761054-762391:+ | gene-YBR279W_NCIM3186 | rna-NM_001178627.1_NCIM3186 | cds-NP_009838.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:737301-738656:+ | gene-YBR279W_NCYC1407 | rna-NM_001178627.1_NCYC1407 | cds-NP_009838.1_NCYC1407 | 97.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:760417-761754:+ | gene-YBR279W_PE2H3 | rna-NM_001178627.1_PE2H3 | cds-NP_009838.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:758093-759430:+ | gene-YBR279W_PE2H4 | rna-NM_001178627.1_PE2H4 | cds-NP_009838.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:761257-762594:+ | gene-YBR279W_S288C | rna-NM_001178627.1_S288C | cds-NP_009838.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:116372-117709:+ | gene-YBR279W_SA1 | rna-NM_001178627.1_SA1 | cds-NP_009838.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:760913-762268:+ | gene-YBR279W_ThermosaccDry | rna-NM_001178627.1_ThermosaccDry | cds-NP_009838.1_ThermosaccDry | 97.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:741117-742454:+ | gene-YBR279W_VR1 | rna-NM_001178627.1_VR1 | cds-NP_009838.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:733757-735111:+ | gene-YBR279W_ZTW1 | rna-NM_001178627.1_ZTW1 | cds-NP_009838.1_ZTW1 | 97.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:777649-778983:+ | gene-YBR279W_Sparadoxus | rna-NM_001178627.1_Sparadoxus | cds-NP_009838.1_Sparadoxus | 86.8 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |