PAC2 (YER007W)


Gene profile

Gene name: PAC2
Reference locus (S288C): YER007W
Gene biotype: protein_coding

Description: Protein PAC2; Microtubule effector required for tubulin heterodimer formation; binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl

Top 10 interactors (score): TUB1 (0.999); CIN1 (0.999); TUB3 (0.999); ALF1 (0.999); RBL2 (0.994); CIN4 (0.979); TUB2 (0.972); CIN2 (0.852); PAC1 (0.839); JNM1 (0.82); YHL008C (0.8); CIN8 (0.794); BIK1 (0.786); ADD66 (0.749); YIL108W (0.748); PBA1 (0.747); YER034W (0.746); IRC25 (0.746); MAD2 (0.72); POC4 (0.712)

Homologues (species, bitscore): TBCE (Homo sapiens, 117.9); Tbce (Mus musculus, 137.9); tbce (Danio rerio, 108.2); tbce (Xenopus tropicalis, 127.5); Tbce (Drosophila melanogaster, 88.6); K07H8.1 (Caenorhabditis elegans, 89.7); PFI (Arabidopsis thaliana, 100.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:158216-159772:+ gene-YER007W_AKU4011 rna-NM_001178898.1_AKU4011 cds-NP_010922.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:265912-267468:- gene-YER007W_BG1 rna-NM_001178898.1_BG1 cds-NP_010922.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:165903-167459:+ gene-YER007W_Bruggeman rna-NM_001178898.1_Bruggeman cds-NP_010922.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:161132-162688:+ gene-YER007W_CAT1 rna-NM_001178898.1_CAT1 cds-NP_010922.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:158525-160081:+ gene-YER007W_CBS1585 rna-NM_001178898.1_CBS1585 cds-NP_010922.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:159794-161350:+ gene-YER007W_CBS436 rna-NM_001178898.1_CBS436 cds-NP_010922.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:158419-159975:+ gene-YER007W_CBS6412 rna-NM_001178898.1_CBS6412 cds-NP_010922.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:163065-164621:+ gene-YER007W_CBS6413 rna-NM_001178898.1_CBS6413 cds-NP_010922.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:162353-163909:+ gene-YER007W_CENPK1137D rna-NM_001178898.1_CENPK1137D cds-NP_010922.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:158880-160436:+ gene-YER007W_EthanolRed rna-NM_001178898.1_EthanolRed cds-NP_010922.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:159140-160696:+ gene-YER007W_FaliES1 rna-NM_001178898.1_FaliES1 cds-NP_010922.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000024.1:26107-27663:+ gene-YER007W_JAY291 rna-NM_001178898.1_JAY291 cds-NP_010922.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:162440-163996:+ gene-YER007W_MUCL30387 rna-NM_001178898.1_MUCL30387 cds-NP_010922.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:158961-160517:+ gene-YER007W_MUCL30388 rna-NM_001178898.1_MUCL30388 cds-NP_010922.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:157561-159117:+ gene-YER007W_MUCL39482 rna-NM_001178898.1_MUCL39482 cds-NP_010922.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:163433-164989:+ gene-YER007W_MUCL42920 rna-NM_001178898.1_MUCL42920 cds-NP_010922.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:164526-166082:+ gene-YER007W_NCIM3186 rna-NM_001178898.1_NCIM3186 cds-NP_010922.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:162635-164191:+ gene-YER007W_NCYC1407 rna-NM_001178898.1_NCYC1407 cds-NP_010922.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:166934-168490:+ gene-YER007W_PE2H3 rna-NM_001178898.1_PE2H3 cds-NP_010922.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:162849-164405:+ gene-YER007W_PE2H4 rna-NM_001178898.1_PE2H4 cds-NP_010922.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:164527-166083:+ gene-YER007W_S288C rna-NM_001178898.1_S288C cds-NP_010922.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:77526-79082:- gene-YER007W_SA1 rna-NM_001178898.1_SA1 cds-NP_010922.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:159546-161102:+ gene-YER007W_ThermosaccDry rna-NM_001178898.1_ThermosaccDry cds-NP_010922.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:159025-160581:+ gene-YER007W_VR1 rna-NM_001178898.1_VR1 cds-NP_010922.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:157576-159132:+ gene-YER007W_ZTW1 rna-NM_001178898.1_ZTW1 cds-NP_010922.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:162284-163843:+ gene-YER007W_Sparadoxus rna-NM_001178898.1_Sparadoxus cds-NP_010922.1_Sparadoxus 86.0 100.0 Unannotated 1 1 0 False False False True False

Additional files