Gene name: PAC11
Reference locus (S288C): YDR488C
Gene biotype: protein_coding
Description: WD repeat-containing protein PAC11; Dynein intermediate chain, microtubule motor protein; required for intracellular transport and cell division; acts in cytoplasmic dynein pathway; forms complex with dynein light chain Dyn2p that promotes Dyn1p homodimerization and potentiates motor processivity; Dyn2p-Pac11p complex is also important for interaction of dynein motor complex with dynactin complex; forms cortical cytoplasmic microtubule capture site with Num1p; essential in the absence of CIN8
Top 10 interactors (score): DYN2 (0.997); DYN1 (0.996); DYN3 (0.99); NIP100 (0.99); NUM1 (0.985); JNM1 (0.921); TUB3 (0.919); KAR9 (0.911); TUB1 (0.908); LDB18 (0.875); TUB2 (0.871); PAC1 (0.869); CIN8 (0.857); NDL1 (0.847); BIM1 (0.81); YPT7 (0.805); PAC10 (0.756); KIP2 (0.748); BIK1 (0.747); SNM1 (0.678)
Homologues (species, bitscore): Sdic4 (Drosophila melanogaster, 55.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1369118-1370716:- | gene-YDR488C_AKU4011 | rna-NM_001180796.1_AKU4011 | cds-NP_010776.1_AKU4011 | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:10720-12318:- | gene-YDR488C_BG1 | rna-NM_001180796.1_BG1 | cds-NP_010776.1_BG1 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1400522-1402120:- | gene-YDR488C_Bruggeman | rna-NM_001180796.1_Bruggeman | cds-NP_010776.1_Bruggeman | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1377666-1379264:- | gene-YDR488C_CAT1 | rna-NM_001180796.1_CAT1 | cds-NP_010776.1_CAT1 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1363417-1365015:- | gene-YDR488C_CBS1585 | rna-NM_001180796.1_CBS1585 | cds-NP_010776.1_CBS1585 | 98.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1382767-1384365:- | gene-YDR488C_CBS436 | rna-NM_001180796.1_CBS436 | cds-NP_010776.1_CBS436 | 99.5 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1359041-1360639:- | gene-YDR488C_CBS6412 | rna-NM_001180796.1_CBS6412 | cds-NP_010776.1_CBS6412 | 98.7 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1382052-1383650:- | gene-YDR488C_CBS6413 | rna-NM_001180796.1_CBS6413 | cds-NP_010776.1_CBS6413 | 98.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1427884-1429485:- | gene-YDR488C_CENPK1137D | rna-NM_001180796.1_CENPK1137D | cds-NP_010776.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1372457-1374055:- | gene-YDR488C_EthanolRed | rna-NM_001180796.1_EthanolRed | cds-NP_010776.1_EthanolRed | 98.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1376010-1377608:- | gene-YDR488C_FaliES1 | rna-NM_001180796.1_FaliES1 | cds-NP_010776.1_FaliES1 | 98.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:74255-75853:- | gene-YDR488C_JAY291 | rna-NM_001180796.1_JAY291 | cds-NP_010776.1_JAY291 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1383008-1384606:- | gene-YDR488C_MUCL30387 | rna-NM_001180796.1_MUCL30387 | cds-NP_010776.1_MUCL30387 | 99.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1365040-1366638:- | gene-YDR488C_MUCL30388 | rna-NM_001180796.1_MUCL30388 | cds-NP_010776.1_MUCL30388 | 99.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1354902-1356500:- | gene-YDR488C_MUCL39482 | rna-NM_001180796.1_MUCL39482 | cds-NP_010776.1_MUCL39482 | 98.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1297683-1299281:- | gene-YDR488C_MUCL42920 | rna-NM_001180796.1_MUCL42920 | cds-NP_010776.1_MUCL42920 | 99.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1429111-1430712:- | gene-YDR488C_NCIM3186 | rna-NM_001180796.1_NCIM3186 | cds-NP_010776.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1368671-1370269:- | gene-YDR488C_NCYC1407 | rna-NM_001180796.1_NCYC1407 | cds-NP_010776.1_NCYC1407 | 98.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1379522-1381120:- | gene-YDR488C_PE2H3 | rna-NM_001180796.1_PE2H3 | cds-NP_010776.1_PE2H3 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1385096-1386694:- | gene-YDR488C_PE2H4 | rna-NM_001180796.1_PE2H4 | cds-NP_010776.1_PE2H4 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1429188-1430789:- | gene-YDR488C_S288C | rna-NM_001180796.1_S288C | cds-NP_010776.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:186360-187958:+ | gene-YDR488C_SA1 | rna-NM_001180796.1_SA1 | cds-NP_010776.1_SA1 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1380232-1381830:- | gene-YDR488C_ThermosaccDry | rna-NM_001180796.1_ThermosaccDry | cds-NP_010776.1_ThermosaccDry | 98.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1395967-1397565:- | gene-YDR488C_VR1 | rna-NM_001180796.1_VR1 | cds-NP_010776.1_VR1 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:422899-424497:- | gene-YDR488C_ZTW1 | rna-NM_001180796.1_ZTW1 | cds-NP_010776.1_ZTW1 | 98.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1383056-1384642:- | gene-YDR488C_Sparadoxus | rna-NM_001180796.1_Sparadoxus | cds-NP_010776.1_Sparadoxus | 84.4 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |