PAB1 (YER165W)


Gene profile

Gene name: PAB1
Reference locus (S288C): YER165W
Gene biotype: protein_coding

Description: Polyadenylate-binding protein, cytoplasmic and nuclear; Poly(A) binding protein; part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G; stimulates, but is not required for the deadenylation activity of the Pan2p-Pan3p poly(A)-ribonuclease complex; Belongs to the polyadenylate-binding protein type-1 family

Top 10 interactors (score): PBP1 (0.999); TIF4631 (0.999); SUP35 (0.999); CDC33 (0.999); TIF4632 (0.999); SCD6 (0.998); DHH1 (0.998); NAM7 (0.996); TIF3 (0.995); TIF1 (0.993); PAN3 (0.992); CBC2 (0.989); STO1 (0.984); TIF2 (0.981); DCP2 (0.98); CCR4 (0.978); XRN1 (0.977); LSM1 (0.974); PAN2 (0.973); PRT1 (0.97)

Homologues (species, bitscore): PABPC1 (Homo sapiens, 486.1); Pabpc1 (Mus musculus, 487.3); pabpc1a (Danio rerio, 490.0); pabpc1 (Xenopus tropicalis, 474.9); pAbp (Drosophila melanogaster, 433.0); pab-1 (Caenorhabditis elegans, 451.1); PAB2 (Arabidopsis thaliana, 446.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:491928-493661:+ gene-YER165W_AKU4011 rna-NM_001179055.1_AKU4011 cds-NP_011092.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000176.1:39714-41447:- gene-YER165W_BG1 rna-NM_001179055.1_BG1 cds-NP_011092.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:504639-506372:+ gene-YER165W_Bruggeman rna-NM_001179055.1_Bruggeman cds-NP_011092.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:491233-492966:+ gene-YER165W_CAT1 rna-NM_001179055.1_CAT1 cds-NP_011092.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:491735-493468:+ gene-YER165W_CBS1585 rna-NM_001179055.1_CBS1585 cds-NP_011092.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:501618-503351:+ gene-YER165W_CBS436 rna-NM_001179055.1_CBS436 cds-NP_011092.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:489712-491445:+ gene-YER165W_CBS6412 rna-NM_001179055.1_CBS6412 cds-NP_011092.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:498281-500014:+ gene-YER165W_CBS6413 rna-NM_001179055.1_CBS6413 cds-NP_011092.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:508144-509877:+ gene-YER165W_CENPK1137D rna-NM_001179055.1_CENPK1137D cds-NP_011092.1_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:497874-499607:+ gene-YER165W_EthanolRed rna-NM_001179055.1_EthanolRed cds-NP_011092.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:498810-500543:+ gene-YER165W_FaliES1 rna-NM_001179055.1_FaliES1 cds-NP_011092.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000169.1:39364-41097:- gene-YER165W_JAY291 rna-NM_001179055.1_JAY291 cds-NP_011092.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:491975-493696:+ gene-YER165W_MUCL30387 rna-NM_001179055.1_MUCL30387 cds-NP_011092.1_MUCL30387 99.0 99.3 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:494881-496620:+ gene-YER165W_MUCL30388 rna-NM_001179055.1_MUCL30388 cds-NP_011092.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:487693-489426:+ gene-YER165W_MUCL39482 rna-NM_001179055.1_MUCL39482 cds-NP_011092.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:502198-503937:+ gene-YER165W_MUCL42920 rna-NM_001179055.1_MUCL42920 cds-NP_011092.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:510372-512105:+ gene-YER165W_NCIM3186 rna-NM_001179055.1_NCIM3186 cds-NP_011092.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:497149-498882:+ gene-YER165W_NCYC1407 rna-NM_001179055.1_NCYC1407 cds-NP_011092.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:513052-514785:+ gene-YER165W_PE2H3 rna-NM_001179055.1_PE2H3 cds-NP_011092.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:502993-504726:+ gene-YER165W_PE2H4 rna-NM_001179055.1_PE2H4 cds-NP_011092.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:510373-512106:+ gene-YER165W_S288C rna-NM_001179055.1_S288C cds-NP_011092.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000030.1:62538-64271:+ gene-YER165W_SA1 rna-NM_001179055.1_SA1 cds-NP_011092.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:499610-501343:+ gene-YER165W_ThermosaccDry rna-NM_001179055.1_ThermosaccDry cds-NP_011092.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:492898-494631:+ gene-YER165W_VR1 rna-NM_001179055.1_VR1 cds-NP_011092.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000011.1:12462-14195:+ gene-YER165W_ZTW1 rna-NM_001179055.1_ZTW1 cds-NP_011092.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:500854-502587:+ gene-YER165W_Sparadoxus rna-NM_001179055.1_Sparadoxus cds-NP_011092.1_Sparadoxus 95.8 100.0 Verified 1 1 1 False True False False False

Additional files