OYE2 (YHR179W)


Gene profile

Gene name: OYE2
Reference locus (S288C): YHR179W
Gene biotype: protein_coding

Description: NADPH dehydrogenase 2; Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN); responsible for geraniol reduction into citronellol during fermentation; homologous to Oye3p with different ligand binding and catalytic properties; may be involved in sterol metabolism, oxidative stress response, and programmed cell death; protein abundance increases in response to DNA replication stress; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family

Top 10 interactors (score): YHR180W (0.76); YHR182W (0.76); GLR1 (0.754); LOT6 (0.742); ENV9 (0.697); SPS19 (0.688); ATF1 (0.678); ARO2 (0.628); YML131W (0.616); OYE3 (0.613); ERG20 (0.608); PST2 (0.586); OAR1 (0.585); FLR1 (0.572); YOR385W (0.57); DUS4 (0.562); YHB1 (0.56); PCS60 (0.554); ARO1 (0.551); FRD1 (0.545)

Homologues (species, bitscore): F17A9.4 (Caenorhabditis elegans, 85.5); OPR3 (Arabidopsis thaliana, 225.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:449589-450791:+ gene-YHR179W_AKU4011 rna-NM_001179310.1_AKU4011 cds-NP_012049.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000141.1:66940-68142:- gene-YHR179W_BG1 rna-NM_001179310.1_BG1 cds-NP_012049.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:456843-458045:+ gene-YHR179W_Bruggeman rna-NM_001179310.1_Bruggeman cds-NP_012049.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:452246-453448:+ gene-YHR179W_CAT1 rna-NM_001179310.1_CAT1 cds-NP_012049.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:449041-450243:+ gene-YHR179W_CBS1585 rna-NM_001179310.1_CBS1585 cds-NP_012049.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:446493-447695:+ gene-YHR179W_CBS436 rna-NM_001179310.1_CBS436 cds-NP_012049.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:449140-450342:+ gene-YHR179W_CBS6412 rna-NM_001179310.1_CBS6412 cds-NP_012049.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:449941-451143:+ gene-YHR179W_CBS6413 rna-NM_001179310.1_CBS6413 cds-NP_012049.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:455683-456885:+ gene-YHR179W_CENPK1137D rna-NM_001179310.1_CENPK1137D cds-NP_012049.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:508136-509338:+ gene-YHR179W_EthanolRed rna-NM_001179310.1_EthanolRed cds-NP_012049.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:450580-451782:+ gene-YHR179W_FaliES1 rna-NM_001179310.1_FaliES1 cds-NP_012049.1_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000376.1:2990-4192:- gene-YHR179W_JAY291 rna-NM_001179310.1_JAY291 cds-NP_012049.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:457917-459119:+ gene-YHR179W_MUCL30387 rna-NM_001179310.1_MUCL30387 cds-NP_012049.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:457356-458558:+ gene-YHR179W_MUCL30388 rna-NM_001179310.1_MUCL30388 cds-NP_012049.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:448952-450154:+ gene-YHR179W_MUCL39482 rna-NM_001179310.1_MUCL39482 cds-NP_012049.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:455572-456774:+ gene-YHR179W_MUCL42920 rna-NM_001179310.1_MUCL42920 cds-NP_012049.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:462384-463586:+ gene-YHR179W_NCIM3186 rna-NM_001179310.1_NCIM3186 cds-NP_012049.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:451411-452613:+ gene-YHR179W_NCYC1407 rna-NM_001179310.1_NCYC1407 cds-NP_012049.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:450564-451766:+ gene-YHR179W_PE2H3 rna-NM_001179310.1_PE2H3 cds-NP_012049.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:457991-459193:+ gene-YHR179W_PE2H4 rna-NM_001179310.1_PE2H4 cds-NP_012049.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:462502-463704:+ gene-YHR179W_S288C rna-NM_001179310.1_S288C cds-NP_012049.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000079.1:10322-11524:+ gene-YHR179W_SA1 rna-NM_001179310.1_SA1 cds-NP_012049.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:451663-452865:+ gene-YHR179W_ThermosaccDry rna-NM_001179310.1_ThermosaccDry cds-NP_012049.1_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:459488-460690:+ gene-YHR179W_VR1 rna-NM_001179310.1_VR1 cds-NP_012049.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:441901-443103:+ gene-YHR179W_ZTW1 rna-NM_001179310.1_ZTW1 cds-NP_012049.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:448111-449313:+ gene-YHR179W_Sparadoxus rna-NM_001179310.1_Sparadoxus cds-NP_012049.1_Sparadoxus 92.6 100.0 Verified 1 1 1 False True False False False

Additional files