OXP1 (YKL215C)


Gene profile

Gene name: OXP1
Reference locus (S288C): YKL215C
Gene biotype: protein_coding

Description: 5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): ECM38 (0.958); GSH1 (0.914); GDH2 (0.903); GCG1 (0.902); TNA1 (0.897); GDH3 (0.892); GDH1 (0.892); YML108W (0.845); GLN1 (0.815); YDL086W (0.814); PUT2 (0.809); GAD1 (0.801); GLT1 (0.8); NNR2 (0.782); AVT2 (0.76); SOF1 (0.735); TSR3 (0.72); ARA2 (0.718); BFR1 (0.702); RPL34B (0.693)

Homologues (species, bitscore): OPLAH (Homo sapiens, 1219.5); Oplah (Mus musculus, 1221.8); OPLAH (Danio rerio, 1226.8); oplah (Xenopus tropicalis, 1204.5); CG4752 (Drosophila melanogaster, 1144.4); Y38F2AR.12 (Caenorhabditis elegans, 1210.3); OXP1 (Arabidopsis thaliana, 1221.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:12656-16516:- gene-YKL215C_AKU4011 rna-NM_001179780.1_AKU4011 cds-NP_012707.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000083.1:8935-12805:+ gene-YKL215C_BG1 rna-NM_001179780.1_BG1 cds-NP_012707.1_BG1 87.3 99.1 Unannotated 1 1 0 False False True False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:30816-34676:- gene-YKL215C_Bruggeman rna-NM_001179780.1_Bruggeman cds-NP_012707.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:25458-29318:- gene-YKL215C_CAT1 rna-NM_001179780.1_CAT1 cds-NP_012707.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:24674-28534:- gene-YKL215C_CBS1585 rna-NM_001179780.1_CBS1585 cds-NP_012707.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:24360-28220:- gene-YKL215C_CBS436 rna-NM_001179780.1_CBS436 cds-NP_012707.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:10803-14663:- gene-YKL215C_CBS6412 rna-NM_001179780.1_CBS6412 cds-NP_012707.1_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:25303-29163:- gene-YKL215C_CBS6413 rna-NM_001179780.1_CBS6413 cds-NP_012707.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:26665-30525:- gene-YKL215C_CENPK1137D rna-NM_001179780.1_CENPK1137D cds-NP_012707.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:24788-28648:- gene-YKL215C_EthanolRed rna-NM_001179780.1_EthanolRed cds-NP_012707.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:24658-28518:- gene-YKL215C_FaliES1 rna-NM_001179780.1_FaliES1 cds-NP_012707.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:24292-28152:- gene-YKL215C_JAY291 rna-NM_001179780.1_JAY291 cds-NP_012707.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:32620-36464:- gene-YKL215C_MUCL30387 rna-NM_001179780.1_MUCL30387 cds-NP_012707.1_MUCL30387 97.8 99.2 Verified 1 1 0 False False True False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:26947-30791:- gene-YKL215C_MUCL30388 rna-NM_001179780.1_MUCL30388 cds-NP_012707.1_MUCL30388 98.0 99.2 Verified 1 1 0 False False True False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:24733-28593:- gene-YKL215C_MUCL39482 rna-NM_001179780.1_MUCL39482 cds-NP_012707.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:28505-32365:- gene-YKL215C_MUCL42920 rna-NM_001179780.1_MUCL42920 cds-NP_012707.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:26816-30676:- gene-YKL215C_NCIM3186 rna-NM_001179780.1_NCIM3186 cds-NP_012707.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:24757-28617:- gene-YKL215C_NCYC1407 rna-NM_001179780.1_NCYC1407 cds-NP_012707.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:32926-36786:- gene-YKL215C_PE2H3 rna-NM_001179780.1_PE2H3 cds-NP_012707.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:29124-32984:- gene-YKL215C_PE2H4 rna-NM_001179780.1_PE2H4 cds-NP_012707.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:26827-30687:- gene-YKL215C_S288C rna-NM_001179780.1_S288C cds-NP_012707.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000161.1:1-2415:+ gene-YKL215C_SA1 rna-NM_001179780.1_SA1 cds-NP_012707.1_SA1 62.3 62.5 Verified 1 1 0 False False True False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:25382-29242:- gene-YKL215C_ThermosaccDry rna-NM_001179780.1_ThermosaccDry cds-NP_012707.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:24541-28401:- gene-YKL215C_VR1 rna-NM_001179780.1_VR1 cds-NP_012707.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:24347-28207:- gene-YKL215C_ZTW1 rna-NM_001179780.1_ZTW1 cds-NP_012707.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:33073-36933:- gene-YKL215C_Sparadoxus rna-NM_001179780.1_Sparadoxus cds-NP_012707.1_Sparadoxus 90.3 99.9 Verified 1 1 1 False True False False False

Additional files