OXA1 (YER154W)


Gene profile

Gene name: OXA1
Reference locus (S288C): YER154W
Gene biotype: protein_coding

Description: Mitochondrial inner membrane insertase; mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane; also has a role in insertion of carrier proteins into the inner membrane; acts as a voltage-gated ion channel, activated by substrate peptides; interacts with mitochondrial ribosomes; conserved from bacteria to animals

Top 10 interactors (score): TOM40 (0.991); COX18 (0.984); MBA1 (0.984); PSD1 (0.976); TIM10 (0.975); ATP6 (0.968); OLI1 (0.96); COX2 (0.956); TIM50 (0.956); COX20 (0.955); YML6 (0.948); EMC3 (0.946); TIM17 (0.945); ATP2 (0.94); ATP23 (0.939); SHY1 (0.931); TIM44 (0.923); MDM38 (0.919); MRPS5 (0.919); MEF1 (0.911)

Homologues (species, bitscore): OXA1L (Homo sapiens, 161.0); Oxa1l (Mus musculus, 158.7); oxa1l (Danio rerio, 164.9); oxa1l (Xenopus tropicalis, 135.2); CG6404 (Drosophila melanogaster, 129.4); C01A2.3 (Caenorhabditis elegans, 104.0); OXA1L (Arabidopsis thaliana, 108.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:462527-463735:+ gene-YER154W_AKU4011 rna-NM_001179044.1_AKU4011 cds-NP_011081.1_AKU4011 99.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000176.1:69309-70517:- gene-YER154W_BG1 rna-NM_001179044.1_BG1 cds-NP_011081.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:473805-475013:+ gene-YER154W_Bruggeman rna-NM_001179044.1_Bruggeman cds-NP_011081.1_Bruggeman 99.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:461650-462858:+ gene-YER154W_CAT1 rna-NM_001179044.1_CAT1 cds-NP_011081.1_CAT1 99.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:462338-463546:+ gene-YER154W_CBS1585 rna-NM_001179044.1_CBS1585 cds-NP_011081.1_CBS1585 99.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:466149-467357:+ gene-YER154W_CBS436 rna-NM_001179044.1_CBS436 cds-NP_011081.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:460856-462064:+ gene-YER154W_CBS6412 rna-NM_001179044.1_CBS6412 cds-NP_011081.1_CBS6412 99.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:468892-470100:+ gene-YER154W_CBS6413 rna-NM_001179044.1_CBS6413 cds-NP_011081.1_CBS6413 99.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:472793-474001:+ gene-YER154W_CENPK1137D rna-NM_001179044.1_CENPK1137D cds-NP_011081.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:468809-470017:+ gene-YER154W_EthanolRed rna-NM_001179044.1_EthanolRed cds-NP_011081.1_EthanolRed 98.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:469395-470603:+ gene-YER154W_FaliES1 rna-NM_001179044.1_FaliES1 cds-NP_011081.1_FaliES1 98.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000111.1:15890-17098:- gene-YER154W_JAY291 rna-NM_001179044.1_JAY291 cds-NP_011081.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:462555-463763:+ gene-YER154W_MUCL30387 rna-NM_001179044.1_MUCL30387 cds-NP_011081.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:465454-466662:+ gene-YER154W_MUCL30388 rna-NM_001179044.1_MUCL30388 cds-NP_011081.1_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:458295-459503:+ gene-YER154W_MUCL39482 rna-NM_001179044.1_MUCL39482 cds-NP_011081.1_MUCL39482 99.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:470622-471830:+ gene-YER154W_MUCL42920 rna-NM_001179044.1_MUCL42920 cds-NP_011081.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:475019-476227:+ gene-YER154W_NCIM3186 rna-NM_001179044.1_NCIM3186 cds-NP_011081.1_NCIM3186 98.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:467761-468969:+ gene-YER154W_NCYC1407 rna-NM_001179044.1_NCYC1407 cds-NP_011081.1_NCYC1407 99.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:483441-484649:+ gene-YER154W_PE2H3 rna-NM_001179044.1_PE2H3 cds-NP_011081.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:473382-474590:+ gene-YER154W_PE2H4 rna-NM_001179044.1_PE2H4 cds-NP_011081.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:475020-476228:+ gene-YER154W_S288C rna-NM_001179044.1_S288C cds-NP_011081.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000030.1:32920-34128:+ gene-YER154W_SA1 rna-NM_001179044.1_SA1 cds-NP_011081.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:470195-471403:+ gene-YER154W_ThermosaccDry rna-NM_001179044.1_ThermosaccDry cds-NP_011081.1_ThermosaccDry 98.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:463305-464513:+ gene-YER154W_VR1 rna-NM_001179044.1_VR1 cds-NP_011081.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000010.1:25154-26362:+ gene-YER154W_ZTW1 rna-NM_001179044.1_ZTW1 cds-NP_011081.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:471205-472413:+ gene-YER154W_Sparadoxus rna-NM_001179044.1_Sparadoxus cds-NP_011081.1_Sparadoxus 91.2 100.0 Verified 1 1 1 False True False False False

Additional files