Gene name: OTU2
Reference locus (S288C): YHL013C
Gene biotype: protein_coding
Description: OTU domain-containing protein 2; Protein of unknown function; may interact with ribosomes, based on co-purification experiments; member of the ovarian tumor-like (OTU) superfamily of predicted cysteine proteases; shows cytoplasmic localization; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): OTU1 (0.984); UBP14 (0.96); UBP9 (0.948); UBP2 (0.941); YUH1 (0.917); RPN11 (0.902); UBP15 (0.898); UBP3 (0.897); UBP6 (0.889); UBP8 (0.875); EST2 (0.874); DOA4 (0.853); UBP12 (0.825); UBP1 (0.811); UFD4 (0.805); RRI1 (0.77); APM2 (0.715); SGN1 (0.695); DUF1 (0.663); UBP10 (0.616)
Homologues (species, bitscore): OTUD6B (Homo sapiens, 140.2); Otud6b (Mus musculus, 140.6); otud6b (Danio rerio, 131.7); otud6b (Xenopus tropicalis, 128.6); CG7857 (Drosophila melanogaster, 126.3); F21D5.2 (Caenorhabditis elegans, 82.4); AT3G62940 (Arabidopsis thaliana, 118.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:72380-73303:- | gene-YHL013C_AKU4011 | rna-NM_001179093.1_AKU4011 | cds-NP_011850.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000180.1:3506-4429:+ | gene-YHL013C_BG1 | rna-NM_001179093.1_BG1 | cds-NP_011850.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:79255-80178:- | gene-YHL013C_Bruggeman | rna-NM_001179093.1_Bruggeman | cds-NP_011850.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:73219-74142:- | gene-YHL013C_CAT1 | rna-NM_001179093.1_CAT1 | cds-NP_011850.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:72982-73905:- | gene-YHL013C_CBS1585 | rna-NM_001179093.1_CBS1585 | cds-NP_011850.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:65465-66388:- | gene-YHL013C_CBS436 | rna-NM_001179093.1_CBS436 | cds-NP_011850.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:72573-73496:- | gene-YHL013C_CBS6412 | rna-NM_001179093.1_CBS6412 | cds-NP_011850.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:72354-73277:- | gene-YHL013C_CBS6413 | rna-NM_001179093.1_CBS6413 | cds-NP_011850.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:70583-71506:- | gene-YHL013C_CENPK1137D | rna-NM_001179093.1_CENPK1137D | cds-NP_011850.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:72385-73308:- | gene-YHL013C_EthanolRed | rna-NM_001179093.1_EthanolRed | cds-NP_011850.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:72916-73839:- | gene-YHL013C_FaliES1 | rna-NM_001179093.1_FaliES1 | cds-NP_011850.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000003.1:41586-42509:- | gene-YHL013C_JAY291 | rna-NM_001179093.1_JAY291 | cds-NP_011850.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:75994-76917:- | gene-YHL013C_MUCL30387 | rna-NM_001179093.1_MUCL30387 | cds-NP_011850.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:76940-77863:- | gene-YHL013C_MUCL30388 | rna-NM_001179093.1_MUCL30388 | cds-NP_011850.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:71992-72915:- | gene-YHL013C_MUCL39482 | rna-NM_001179093.1_MUCL39482 | cds-NP_011850.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:75910-76833:- | gene-YHL013C_MUCL42920 | rna-NM_001179093.1_MUCL42920 | cds-NP_011850.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:77312-78235:- | gene-YHL013C_NCIM3186 | rna-NM_001179093.1_NCIM3186 | cds-NP_011850.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:71419-72342:- | gene-YHL013C_NCYC1407 | rna-NM_001179093.1_NCYC1407 | cds-NP_011850.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:67661-68584:- | gene-YHL013C_PE2H3 | rna-NM_001179093.1_PE2H3 | cds-NP_011850.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:75102-76025:- | gene-YHL013C_PE2H4 | rna-NM_001179093.1_PE2H4 | cds-NP_011850.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:77430-78353:- | gene-YHL013C_S288C | rna-NM_001179093.1_S288C | cds-NP_011850.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:61755-62678:- | gene-YHL013C_SA1 | rna-NM_001179093.1_SA1 | cds-NP_011850.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:74011-74934:- | gene-YHL013C_ThermosaccDry | rna-NM_001179093.1_ThermosaccDry | cds-NP_011850.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:78737-79660:- | gene-YHL013C_VR1 | rna-NM_001179093.1_VR1 | cds-NP_011850.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:65178-66101:- | gene-YHL013C_ZTW1 | rna-NM_001179093.1_ZTW1 | cds-NP_011850.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:71530-72477:- | gene-YHL013C_Sparadoxus | rna-NM_001179093.1_Sparadoxus | cds-NP_011850.1_Sparadoxus | 85.1 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |