Gene name: OTU1
Reference locus (S288C): YFL044C
Gene biotype: protein_coding
Description: Ubiquitin thioesterase OTU1; Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): CDC48 (0.999); UBI4 (0.994); OTU2 (0.984); UFD2 (0.96); UBP14 (0.959); UFD1 (0.957); NPL4 (0.957); RPS31 (0.953); DOA1 (0.907); UBP6 (0.902); UBX2 (0.882); RPL40A (0.879); RPL40B (0.877); UBP9 (0.876); UBP2 (0.86); RPN11 (0.856); UBP15 (0.844); DOA4 (0.824); UBP3 (0.814); SHP1 (0.809)
Homologues (species, bitscore): YOD1 (Homo sapiens, 145.6); Yod1 (Mus musculus, 150.2); yod1 (Danio rerio, 151.0); yod1 (Xenopus tropicalis, 138.7); CG4603 (Drosophila melanogaster, 137.9); AT1G50670 (Arabidopsis thaliana, 122.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:40992-41897:- | gene-YFL044C_AKU4011 | rna-NM_001179923.1_AKU4011 | cds-NP_116610.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000182.1:27896-28801:+ | gene-YFL044C_BG1 | rna-NM_001179923.1_BG1 | cds-NP_116610.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:39370-40275:- | gene-YFL044C_Bruggeman | rna-NM_001179923.1_Bruggeman | cds-NP_116610.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:44758-45663:- | gene-YFL044C_CAT1 | rna-NM_001179923.1_CAT1 | cds-NP_116610.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:41669-42574:- | gene-YFL044C_CBS1585 | rna-NM_001179923.1_CBS1585 | cds-NP_116610.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:15303-16208:- | gene-YFL044C_CBS436 | rna-NM_001179923.1_CBS436 | cds-NP_116610.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:41909-42814:- | gene-YFL044C_CBS6412 | rna-NM_001179923.1_CBS6412 | cds-NP_116610.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:44070-44975:- | gene-YFL044C_CBS6413 | rna-NM_001179923.1_CBS6413 | cds-NP_116610.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:40981-41886:- | gene-YFL044C_CENPK1137D | rna-NM_001179923.1_CENPK1137D | cds-NP_116610.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:40336-41241:- | gene-YFL044C_EthanolRed | rna-NM_001179923.1_EthanolRed | cds-NP_116610.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:41544-42449:- | gene-YFL044C_FaliES1 | rna-NM_001179923.1_FaliES1 | cds-NP_116610.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000448.1:50001-50906:- | gene-YFL044C_JAY291 | rna-NM_001179923.1_JAY291 | cds-NP_116610.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:41959-42864:- | gene-YFL044C_MUCL30387 | rna-NM_001179923.1_MUCL30387 | cds-NP_116610.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:38982-39887:- | gene-YFL044C_MUCL30388 | rna-NM_001179923.1_MUCL30388 | cds-NP_116610.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:40185-41090:- | gene-YFL044C_MUCL39482 | rna-NM_001179923.1_MUCL39482 | cds-NP_116610.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:37888-38793:- | gene-YFL044C_MUCL42920 | rna-NM_001179923.1_MUCL42920 | cds-NP_116610.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:44654-45559:- | gene-YFL044C_NCIM3186 | rna-NM_001179923.1_NCIM3186 | cds-NP_116610.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:41262-42167:- | gene-YFL044C_NCYC1407 | rna-NM_001179923.1_NCYC1407 | cds-NP_116610.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:61155-62060:- | gene-YFL044C_PE2H3 | rna-NM_001179923.1_PE2H3 | cds-NP_116610.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:60706-61611:- | gene-YFL044C_PE2H4 | rna-NM_001179923.1_PE2H4 | cds-NP_116610.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:44655-45560:- | gene-YFL044C_S288C | rna-NM_001179923.1_S288C | cds-NP_116610.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:290073-290978:+ | gene-YFL044C_SA1 | rna-NM_001179923.1_SA1 | cds-NP_116610.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:40732-41637:- | gene-YFL044C_ThermosaccDry | rna-NM_001179923.1_ThermosaccDry | cds-NP_116610.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:49275-50180:- | gene-YFL044C_VR1 | rna-NM_001179923.1_VR1 | cds-NP_116610.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000012.1:26029-26934:- | gene-YFL044C_ZTW1 | rna-NM_001179923.1_ZTW1 | cds-NP_116610.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:65042-65950:- | gene-YFL044C_Sparadoxus | rna-NM_001179923.1_Sparadoxus | cds-NP_116610.1_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |