OSH7 (YHR001W)


Gene profile

Gene name: OSH7
Reference locus (S288C): YHR001W
Gene biotype: protein_coding

Description: Oxysterol-binding protein; part of family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; OSH7 has a paralog, OSH6, that arose from the whole genome duplication

Top 10 interactors (score): OSH6 (0.999); SAC1 (0.9); VPS4 (0.887); PIK1 (0.862); SEC14 (0.843); SCS2 (0.82); KES1 (0.75); STT4 (0.672); HES1 (0.667); PAP1 (0.661); LCB1 (0.575); AGE2 (0.573); UPS1 (0.567); SWH1 (0.553); NCR1 (0.542); IST2 (0.497); NSP1 (0.468); PRY1 (0.45); MID2 (0.44); OSH3 (0.436)

Homologues (species, bitscore): OSBPL5 (Homo sapiens, 231.1); Osbpl9 (Mus musculus, 226.5); osbpl9 (Danio rerio, 213.8); osbpl8 (Xenopus tropicalis, 226.9); CG42668 (Drosophila melanogaster, 226.1); obr-3 (Caenorhabditis elegans, 228.4); ORP4C (Arabidopsis thaliana, 96.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:94668-95981:+ gene-YHR001W_AKU4011 rna-NM_001179131.1_AKU4011 cds-NP_011863.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:14383-15696:+ gene-YHR001W_BG1 rna-NM_001179131.1_BG1 cds-NP_011863.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:101525-102838:+ gene-YHR001W_Bruggeman rna-NM_001179131.1_Bruggeman cds-NP_011863.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:95509-96822:+ gene-YHR001W_CAT1 rna-NM_001179131.1_CAT1 cds-NP_011863.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:95255-96568:+ gene-YHR001W_CBS1585 rna-NM_001179131.1_CBS1585 cds-NP_011863.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:87752-89065:+ gene-YHR001W_CBS436 rna-NM_001179131.1_CBS436 cds-NP_011863.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:94854-96167:+ gene-YHR001W_CBS6412 rna-NM_001179131.1_CBS6412 cds-NP_011863.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:94580-95893:+ gene-YHR001W_CBS6413 rna-NM_001179131.1_CBS6413 cds-NP_011863.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:99212-100525:+ gene-YHR001W_CENPK1137D rna-NM_001179131.1_CENPK1137D cds-NP_011863.1_CENPK1137D 99.8 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:94664-95977:+ gene-YHR001W_EthanolRed rna-NM_001179131.1_EthanolRed cds-NP_011863.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:95193-96506:+ gene-YHR001W_FaliES1 rna-NM_001179131.1_FaliES1 cds-NP_011863.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000064.1:25455-26768:- gene-YHR001W_JAY291 rna-NM_001179131.1_JAY291 cds-NP_011863.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:98265-99578:+ gene-YHR001W_MUCL30387 rna-NM_001179131.1_MUCL30387 cds-NP_011863.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:99476-100789:+ gene-YHR001W_MUCL30388 rna-NM_001179131.1_MUCL30388 cds-NP_011863.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:94281-95594:+ gene-YHR001W_MUCL39482 rna-NM_001179131.1_MUCL39482 cds-NP_011863.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:98187-99500:+ gene-YHR001W_MUCL42920 rna-NM_001179131.1_MUCL42920 cds-NP_011863.1_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:105937-107250:+ gene-YHR001W_NCIM3186 rna-NM_001179131.1_NCIM3186 cds-NP_011863.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:93697-95010:+ gene-YHR001W_NCYC1407 rna-NM_001179131.1_NCYC1407 cds-NP_011863.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:95902-97215:+ gene-YHR001W_PE2H3 rna-NM_001179131.1_PE2H3 cds-NP_011863.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:103343-104656:+ gene-YHR001W_PE2H4 rna-NM_001179131.1_PE2H4 cds-NP_011863.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:106055-107368:+ gene-YHR001W_S288C rna-NM_001179131.1_S288C cds-NP_011863.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000075.1:39175-40488:- gene-YHR001W_SA1 rna-NM_001179131.1_SA1 cds-NP_011863.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:96283-97596:+ gene-YHR001W_ThermosaccDry rna-NM_001179131.1_ThermosaccDry cds-NP_011863.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:101829-103142:+ gene-YHR001W_VR1 rna-NM_001179131.1_VR1 cds-NP_011863.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:87447-88760:+ gene-YHR001W_ZTW1 rna-NM_001179131.1_ZTW1 cds-NP_011863.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:94015-95328:+ gene-YHR001W_Sparadoxus rna-NM_001179131.1_Sparadoxus cds-NP_011863.1_Sparadoxus 91.7 100.0 Verified 1 1 1 False True False False False

Additional files