Gene name: OSH3
Reference locus (S288C): YHR073W
Gene biotype: protein_coding
Description: Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane; regulated by sterol binding; Belongs to the OSBP family
Top 10 interactors (score): SCS2 (0.998); KES1 (0.976); SAC1 (0.954); STT4 (0.877); SCS22 (0.813); EFR3 (0.81); OPI1 (0.78); INO1 (0.78); YPP1 (0.728); HES1 (0.706); OSH2 (0.689); SEC14 (0.676); ROK1 (0.606); SWA2 (0.605); SWH1 (0.577); YPT7 (0.568); YHR214C-E (0.561); YHR214C-D (0.561); ICE2 (0.543); ARP2 (0.534)
Homologues (species, bitscore): OSBPL7 (Homo sapiens, 237.7); Osbpl3 (Mus musculus, 253.8); osbpl3a (Danio rerio, 250.4); osbpl1a (Xenopus tropicalis, 216.1); Osbp (Drosophila melanogaster, 210.3); obr-2 (Caenorhabditis elegans, 199.1); ORP1B (Arabidopsis thaliana, 202.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:228997-231987:+ | gene-YHR073W_AKU4011 | rna-NM_001179203.1_AKU4011 | cds-NP_011940.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:149349-152339:+ | gene-YHR073W_BG1 | rna-NM_001179203.1_BG1 | cds-NP_011940.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:236829-239819:+ | gene-YHR073W_Bruggeman | rna-NM_001179203.1_Bruggeman | cds-NP_011940.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:231471-234461:+ | gene-YHR073W_CAT1 | rna-NM_001179203.1_CAT1 | cds-NP_011940.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:228037-231027:+ | gene-YHR073W_CBS1585 | rna-NM_001179203.1_CBS1585 | cds-NP_011940.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:225902-228892:+ | gene-YHR073W_CBS436 | rna-NM_001179203.1_CBS436 | cds-NP_011940.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:231383-234373:+ | gene-YHR073W_CBS6412 | rna-NM_001179203.1_CBS6412 | cds-NP_011940.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:229078-232068:+ | gene-YHR073W_CBS6413 | rna-NM_001179203.1_CBS6413 | cds-NP_011940.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:235752-238742:+ | gene-YHR073W_CENPK1137D | rna-NM_001179203.1_CENPK1137D | cds-NP_011940.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:288595-291585:+ | gene-YHR073W_EthanolRed | rna-NM_001179203.1_EthanolRed | cds-NP_011940.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:229399-232389:+ | gene-YHR073W_FaliES1 | rna-NM_001179203.1_FaliES1 | cds-NP_011940.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000394.1:12143-15133:+ | gene-YHR073W_JAY291 | rna-NM_001179203.1_JAY291 | cds-NP_011940.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:236339-239329:+ | gene-YHR073W_MUCL30387 | rna-NM_001179203.1_MUCL30387 | cds-NP_011940.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:236207-239197:+ | gene-YHR073W_MUCL30388 | rna-NM_001179203.1_MUCL30388 | cds-NP_011940.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:228362-231352:+ | gene-YHR073W_MUCL39482 | rna-NM_001179203.1_MUCL39482 | cds-NP_011940.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:235106-238096:+ | gene-YHR073W_MUCL42920 | rna-NM_001179203.1_MUCL42920 | cds-NP_011940.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:242464-245454:+ | gene-YHR073W_NCIM3186 | rna-NM_001179203.1_NCIM3186 | cds-NP_011940.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:230826-233816:+ | gene-YHR073W_NCYC1407 | rna-NM_001179203.1_NCYC1407 | cds-NP_011940.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:230507-233497:+ | gene-YHR073W_PE2H3 | rna-NM_001179203.1_PE2H3 | cds-NP_011940.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:237954-240944:+ | gene-YHR073W_PE2H4 | rna-NM_001179203.1_PE2H4 | cds-NP_011940.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:242582-245572:+ | gene-YHR073W_S288C | rna-NM_001179203.1_S288C | cds-NP_011940.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:113412-116402:- | gene-YHR073W_SA1 | rna-NM_001179203.1_SA1 | cds-NP_011940.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:230490-233480:+ | gene-YHR073W_ThermosaccDry | rna-NM_001179203.1_ThermosaccDry | cds-NP_011940.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:238133-241123:+ | gene-YHR073W_VR1 | rna-NM_001179203.1_VR1 | cds-NP_011940.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:222042-225032:+ | gene-YHR073W_ZTW1 | rna-NM_001179203.1_ZTW1 | cds-NP_011940.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:227840-230830:+ | gene-YHR073W_Sparadoxus | rna-NM_001179203.1_Sparadoxus | cds-NP_011940.1_Sparadoxus | 89.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |