Gene name: ORT1
Reference locus (S288C): YOR130C
Gene biotype: protein_coding
Description: Ornithine transporter of the mitochondrial inner membrane; exports ornithine from mitochondria as part of arginine biosynthesis; functionally complemented by human ortholog, SLC25A15, which is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome, but HHH-associated variants fail to complement
Top 10 interactors (score): ARG5,6 (0.952); ARG7 (0.94); YGL117W (0.926); ARG4 (0.902); CPA1 (0.839); ARG2 (0.818); ARG3 (0.809); ARG8 (0.782); CAR1 (0.771); SPE1 (0.762); STR2 (0.757); CYT1 (0.744); ARG1 (0.72); COX6 (0.698); TMT1 (0.696); QCR7 (0.684); YBR225W (0.658); QCR2 (0.652); RIB5 (0.632); YMC1 (0.609)
Homologues (species, bitscore): SLC25A2 (Homo sapiens, 131.0); Slc25a15 (Mus musculus, 125.9); slc25a29 (Danio rerio, 136.3); LOC100495907 (Xenopus tropicalis, 131.3); CG1628 (Drosophila melanogaster, 136.3); C54G10.4 (Caenorhabditis elegans, 125.9); BOU (Arabidopsis thaliana, 136.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:553994-554872:- | gene-YOR130C_AKU4011 | rna-NM_001183549.4_AKU4011 | cds-NP_014773.4_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:24400-25278:+ | gene-YOR130C_BG1 | rna-NM_001183549.4_BG1 | cds-NP_014773.4_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:557539-558417:- | gene-YOR130C_Bruggeman | rna-NM_001183549.4_Bruggeman | cds-NP_014773.4_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:557550-558428:- | gene-YOR130C_CAT1 | rna-NM_001183549.4_CAT1 | cds-NP_014773.4_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:549556-550434:- | gene-YOR130C_CBS1585 | rna-NM_001183549.4_CBS1585 | cds-NP_014773.4_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:554264-555142:- | gene-YOR130C_CBS436 | rna-NM_001183549.4_CBS436 | cds-NP_014773.4_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:548042-548920:- | gene-YOR130C_CBS6412 | rna-NM_001183549.4_CBS6412 | cds-NP_014773.4_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:555338-556216:- | gene-YOR130C_CBS6413 | rna-NM_001183549.4_CBS6413 | cds-NP_014773.4_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:570005-570883:- | gene-YOR130C_CENPK1137D | rna-NM_001183549.4_CENPK1137D | cds-NP_014773.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:550365-551243:- | gene-YOR130C_EthanolRed | rna-NM_001183549.4_EthanolRed | cds-NP_014773.4_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:554061-554939:- | gene-YOR130C_FaliES1 | rna-NM_001183549.4_FaliES1 | cds-NP_014773.4_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000063.1:4328-5206:+ | gene-YOR130C_JAY291 | rna-NM_001183549.4_JAY291 | cds-NP_014773.4_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:562097-562975:- | gene-YOR130C_MUCL30387 | rna-NM_001183549.4_MUCL30387 | cds-NP_014773.4_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:567305-568183:- | gene-YOR130C_MUCL30388 | rna-NM_001183549.4_MUCL30388 | cds-NP_014773.4_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:556951-557829:- | gene-YOR130C_MUCL39482 | rna-NM_001183549.4_MUCL39482 | cds-NP_014773.4_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:572997-573875:- | gene-YOR130C_MUCL42920 | rna-NM_001183549.4_MUCL42920 | cds-NP_014773.4_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:569818-570696:- | gene-YOR130C_NCIM3186 | rna-NM_001183549.4_NCIM3186 | cds-NP_014773.4_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:563398-564276:- | gene-YOR130C_NCYC1407 | rna-NM_001183549.4_NCYC1407 | cds-NP_014773.4_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:562401-563279:- | gene-YOR130C_PE2H3 | rna-NM_001183549.4_PE2H3 | cds-NP_014773.4_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:572778-573656:- | gene-YOR130C_PE2H4 | rna-NM_001183549.4_PE2H4 | cds-NP_014773.4_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:569929-570807:- | gene-YOR130C_S288C | rna-NM_001183549.4_S288C | cds-NP_014773.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:99472-100350:- | gene-YOR130C_SA1 | rna-NM_001183549.4_SA1 | cds-NP_014773.4_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:553244-554122:- | gene-YOR130C_ThermosaccDry | rna-NM_001183549.4_ThermosaccDry | cds-NP_014773.4_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:555348-556226:- | gene-YOR130C_VR1 | rna-NM_001183549.4_VR1 | cds-NP_014773.4_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:287177-288055:- | gene-YOR130C_ZTW1 | rna-NM_001183549.4_ZTW1 | cds-NP_014773.4_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:559182-560060:- | gene-YOR130C_Sparadoxus | rna-NM_001183549.4_Sparadoxus | cds-NP_014773.4_Sparadoxus | 89.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |