Gene name: ORM1
Reference locus (S288C): YGR038W
Gene biotype: protein_coding
Description: Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; ORM1 has a paralog, ORM2, that arose from the whole genome duplication
Top 10 interactors (score): ORM2 (0.999); LCB1 (0.997); TSC3 (0.994); LCB2 (0.993); SAC1 (0.992); YPK1 (0.923); LAC1 (0.861); YPK2 (0.815); LAG1 (0.805); FPK1 (0.803); SLM1 (0.793); NPR1 (0.786); KIN82 (0.785); PKH1 (0.776); AUR1 (0.772); LCB4 (0.735); ERF2 (0.722); SHR5 (0.72); DNF1 (0.716); YPC1 (0.699)
Homologues (species, bitscore): ORMDL3 (Homo sapiens, 90.1); Ormdl3 (Mus musculus, 89.4); ormdl3 (Danio rerio, 84.0); ormdl2 (Xenopus tropicalis, 85.5); ORMDL (Drosophila melanogaster, 82.8); AT5G42000 (Arabidopsis thaliana, 85.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:556286-556954:+ | gene-YGR038W_AKU4011 | rna-NM_001181167.1_AKU4011 | cds-NP_011552.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:18902-19570:- | gene-YGR038W_BG1 | rna-NM_001181167.1_BG1 | cds-NP_011552.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:558561-559229:+ | gene-YGR038W_Bruggeman | rna-NM_001181167.1_Bruggeman | cds-NP_011552.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:556619-557287:+ | gene-YGR038W_CAT1 | rna-NM_001181167.1_CAT1 | cds-NP_011552.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:557598-558266:+ | gene-YGR038W_CBS1585 | rna-NM_001181167.1_CBS1585 | cds-NP_011552.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:552401-553069:+ | gene-YGR038W_CBS436 | rna-NM_001181167.1_CBS436 | cds-NP_011552.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:550374-551042:+ | gene-YGR038W_CBS6412 | rna-NM_001181167.1_CBS6412 | cds-NP_011552.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:554374-555042:+ | gene-YGR038W_CBS6413 | rna-NM_001181167.1_CBS6413 | cds-NP_011552.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:560508-561176:+ | gene-YGR038W_CENPK1137D | rna-NM_001181167.1_CENPK1137D | cds-NP_011552.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:544503-545171:+ | gene-YGR038W_EthanolRed | rna-NM_001181167.1_EthanolRed | cds-NP_011552.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:547987-548655:+ | gene-YGR038W_FaliES1 | rna-NM_001181167.1_FaliES1 | cds-NP_011552.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000020.1:86691-87359:+ | gene-YGR038W_JAY291 | rna-NM_001181167.1_JAY291 | cds-NP_011552.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:555194-555862:+ | gene-YGR038W_MUCL30387 | rna-NM_001181167.1_MUCL30387 | cds-NP_011552.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:557809-558477:+ | gene-YGR038W_MUCL30388 | rna-NM_001181167.1_MUCL30388 | cds-NP_011552.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:553418-554086:+ | gene-YGR038W_MUCL39482 | rna-NM_001181167.1_MUCL39482 | cds-NP_011552.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:563212-563880:+ | gene-YGR038W_MUCL42920 | rna-NM_001181167.1_MUCL42920 | cds-NP_011552.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:560682-561350:+ | gene-YGR038W_NCIM3186 | rna-NM_001181167.1_NCIM3186 | cds-NP_011552.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:547613-548281:+ | gene-YGR038W_NCYC1407 | rna-NM_001181167.1_NCYC1407 | cds-NP_011552.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:550516-551184:+ | gene-YGR038W_PE2H3 | rna-NM_001181167.1_PE2H3 | cds-NP_011552.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:555623-556291:+ | gene-YGR038W_PE2H4 | rna-NM_001181167.1_PE2H4 | cds-NP_011552.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:560682-561350:+ | gene-YGR038W_S288C | rna-NM_001181167.1_S288C | cds-NP_011552.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:587-1255:- | gene-YGR038W_SA1 | rna-NM_001181167.1_SA1 | cds-NP_011552.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:567324-567992:+ | gene-YGR038W_ThermosaccDry | rna-NM_001181167.1_ThermosaccDry | cds-NP_011552.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:657747-658415:+ | gene-YGR038W_VR1 | rna-NM_001181167.1_VR1 | cds-NP_011552.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:22808-23476:+ | gene-YGR038W_ZTW1 | rna-NM_001181167.1_ZTW1 | cds-NP_011552.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:556844-557512:+ | gene-YGR038W_Sparadoxus | rna-NM_001181167.1_Sparadoxus | cds-NP_011552.1_Sparadoxus | 92.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |