Gene name: ORC4
Reference locus (S288C): YPR162C
Gene biotype: protein_coding
Description: Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; ORC4 has a paralog, RIF2, that arose from the whole genome duplication
Top 10 interactors (score): ORC2 (0.999); MCM7 (0.999); MCM2 (0.999); MCM6 (0.999); ORC3 (0.999); CDC6 (0.999); ORC5 (0.999); MCM3 (0.999); MCM5 (0.999); ORC1 (0.999); MCM4 (0.999); CDC45 (0.998); DPB2 (0.998); ORC6 (0.998); POL12 (0.997); POL1 (0.996); PRI2 (0.994); TAH11 (0.988); POL2 (0.987); PSF3 (0.984)
Homologues (species, bitscore): ORC4 (Homo sapiens, 122.9); Orc4 (Mus musculus, 124.8); orc4 (Danio rerio, 118.6); orc4 (Xenopus tropicalis, 92.0); Orc4 (Drosophila melanogaster, 118.2); ORC4 (Arabidopsis thaliana, 80.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:820992-822581:- | gene-YPR162C_AKU4011 | rna-NM_001184259.1_AKU4011 | cds-NP_015488.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:75135-76724:+ | gene-YPR162C_BG1 | rna-NM_001184259.1_BG1 | cds-NP_015488.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:901184-902773:- | gene-YPR162C_Bruggeman | rna-NM_001184259.1_Bruggeman | cds-NP_015488.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:943790-945379:- | gene-YPR162C_CAT1 | rna-NM_001184259.1_CAT1 | cds-NP_015488.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:825792-827381:- | gene-YPR162C_CBS1585 | rna-NM_001184259.1_CBS1585 | cds-NP_015488.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:839347-840936:- | gene-YPR162C_CBS436 | rna-NM_001184259.1_CBS436 | cds-NP_015488.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:827656-829245:- | gene-YPR162C_CBS6412 | rna-NM_001184259.1_CBS6412 | cds-NP_015488.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:822722-824311:- | gene-YPR162C_CBS6413 | rna-NM_001184259.1_CBS6413 | cds-NP_015488.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:866726-868315:- | gene-YPR162C_CENPK1137D | rna-NM_001184259.1_CENPK1137D | cds-NP_015488.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1142626-1144215:- | gene-YPR162C_EthanolRed | rna-NM_001184259.1_EthanolRed | cds-NP_015488.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:822332-823921:- | gene-YPR162C_FaliES1 | rna-NM_001184259.1_FaliES1 | cds-NP_015488.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000081.1:10123-11712:- | gene-YPR162C_JAY291 | rna-NM_001184259.1_JAY291 | cds-NP_015488.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:869269-870858:- | gene-YPR162C_MUCL30387 | rna-NM_001184259.1_MUCL30387 | cds-NP_015488.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:841848-843437:- | gene-YPR162C_MUCL30388 | rna-NM_001184259.1_MUCL30388 | cds-NP_015488.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:817994-819583:- | gene-YPR162C_MUCL39482 | rna-NM_001184259.1_MUCL39482 | cds-NP_015488.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:881656-883245:- | gene-YPR162C_MUCL42920 | rna-NM_001184259.1_MUCL42920 | cds-NP_015488.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:866698-868287:- | gene-YPR162C_NCIM3186 | rna-NM_001184259.1_NCIM3186 | cds-NP_015488.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:826355-827944:- | gene-YPR162C_NCYC1407 | rna-NM_001184259.1_NCYC1407 | cds-NP_015488.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:838647-840236:- | gene-YPR162C_PE2H3 | rna-NM_001184259.1_PE2H3 | cds-NP_015488.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:838295-839884:- | gene-YPR162C_PE2H4 | rna-NM_001184259.1_PE2H4 | cds-NP_015488.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:866715-868304:- | gene-YPR162C_S288C | rna-NM_001184259.1_S288C | cds-NP_015488.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000060.1:57855-59444:+ | gene-YPR162C_SA1 | rna-NM_001184259.1_SA1 | cds-NP_015488.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:822020-823609:- | gene-YPR162C_ThermosaccDry | rna-NM_001184259.1_ThermosaccDry | cds-NP_015488.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:850302-851891:- | gene-YPR162C_VR1 | rna-NM_001184259.1_VR1 | cds-NP_015488.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:825142-826731:- | gene-YPR162C_ZTW1 | rna-NM_001184259.1_ZTW1 | cds-NP_015488.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:827201-828790:- | gene-YPR162C_Sparadoxus | rna-NM_001184259.1_Sparadoxus | cds-NP_015488.1_Sparadoxus | 89.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |