Gene name: ORC2
Reference locus (S288C): YBR060C
Gene biotype: protein_coding
Description: Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28p
Top 10 interactors (score): MCM3 (0.999); MCM10 (0.999); MCM6 (0.999); MCM2 (0.999); MCM7 (0.999); ORC3 (0.999); ORC5 (0.999); MCM5 (0.999); CDC6 (0.999); ORC6 (0.999); ORC4 (0.999); ORC1 (0.999); MCM4 (0.999); CDC28 (0.998); TAH11 (0.998); CDC45 (0.998); POL1 (0.995); POL2 (0.995); POL12 (0.993); DBF4 (0.992)
Homologues (species, bitscore): ORC2 (Homo sapiens, 136.7); Orc2 (Mus musculus, 137.5); ORC2 (Danio rerio, 94.0); orc2 (Xenopus tropicalis, 127.1); Orc2 (Drosophila melanogaster, 151.0); orc-2 (Caenorhabditis elegans, 78.2); ORC2 (Arabidopsis thaliana, 141.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:343068-344930:- | gene-YBR060C_AKU4011 | rna-NM_001178408.1_AKU4011 | cds-NP_009616.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:333281-335143:- | gene-YBR060C_BG1 | rna-NM_001178408.1_BG1 | cds-NP_009616.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:343788-345650:- | gene-YBR060C_Bruggeman | rna-NM_001178408.1_Bruggeman | cds-NP_009616.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:347550-349412:- | gene-YBR060C_CAT1 | rna-NM_001178408.1_CAT1 | cds-NP_009616.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:335349-337211:- | gene-YBR060C_CBS1585 | rna-NM_001178408.1_CBS1585 | cds-NP_009616.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:343384-345246:- | gene-YBR060C_CBS436 | rna-NM_001178408.1_CBS436 | cds-NP_009616.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:433567-435429:- | gene-YBR060C_CBS6412 | rna-NM_001178408.1_CBS6412 | cds-NP_009616.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:340473-342335:- | gene-YBR060C_CBS6413 | rna-NM_001178408.1_CBS6413 | cds-NP_009616.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:354414-356276:- | gene-YBR060C_CENPK1137D | rna-NM_001178408.1_CENPK1137D | cds-NP_009616.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:469836-471698:- | gene-YBR060C_EthanolRed | rna-NM_001178408.1_EthanolRed | cds-NP_009616.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:359114-360976:- | gene-YBR060C_FaliES1 | rna-NM_001178408.1_FaliES1 | cds-NP_009616.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000124.1:7008-8870:- | gene-YBR060C_JAY291 | rna-NM_001178408.1_JAY291 | cds-NP_009616.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:345412-347274:- | gene-YBR060C_MUCL30387 | rna-NM_001178408.1_MUCL30387 | cds-NP_009616.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:345190-347052:- | gene-YBR060C_MUCL30388 | rna-NM_001178408.1_MUCL30388 | cds-NP_009616.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:335337-337199:- | gene-YBR060C_MUCL39482 | rna-NM_001178408.1_MUCL39482 | cds-NP_009616.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:342536-344398:- | gene-YBR060C_MUCL42920 | rna-NM_001178408.1_MUCL42920 | cds-NP_009616.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:360449-362311:- | gene-YBR060C_NCIM3186 | rna-NM_001178408.1_NCIM3186 | cds-NP_009616.1_NCIM3186 | 95.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:336255-338117:- | gene-YBR060C_NCYC1407 | rna-NM_001178408.1_NCYC1407 | cds-NP_009616.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:348479-350341:- | gene-YBR060C_PE2H3 | rna-NM_001178408.1_PE2H3 | cds-NP_009616.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:346155-348017:- | gene-YBR060C_PE2H4 | rna-NM_001178408.1_PE2H4 | cds-NP_009616.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:360652-362514:- | gene-YBR060C_S288C | rna-NM_001178408.1_S288C | cds-NP_009616.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:115007-116869:+ | gene-YBR060C_SA1 | rna-NM_001178408.1_SA1 | cds-NP_009616.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:358125-359987:- | gene-YBR060C_ThermosaccDry | rna-NM_001178408.1_ThermosaccDry | cds-NP_009616.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:340074-341936:- | gene-YBR060C_VR1 | rna-NM_001178408.1_VR1 | cds-NP_009616.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:333812-335674:- | gene-YBR060C_ZTW1 | rna-NM_001178408.1_ZTW1 | cds-NP_009616.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:370820-372682:- | gene-YBR060C_Sparadoxus | rna-NM_001178408.1_Sparadoxus | cds-NP_009616.1_Sparadoxus | 87.8 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |