Gene name: ORC1
Reference locus (S288C): YML065W
Gene biotype: protein_coding
Description: Largest subunit of the origin recognition complex; involved in directing DNA replication by binding to replication origins; also involved in transcriptional silencing; exhibits ATPase activity; ORC1 has a paralog, SIR3, that arose from the whole genome duplication
Top 10 interactors (score): SIR1 (0.999); ORC4 (0.999); ORC2 (0.999); MCM4 (0.999); CDC6 (0.999); ORC5 (0.999); ORC6 (0.999); MCM3 (0.999); MCM5 (0.999); MCM7 (0.999); MCM6 (0.999); MCM2 (0.999); CDC45 (0.999); ORC3 (0.999); TAH11 (0.998); MCM10 (0.995); CHK1 (0.992); CDC28 (0.989); POL1 (0.988); POL2 (0.987)
Homologues (species, bitscore): ORC1 (Homo sapiens, 211.8); Orc1 (Mus musculus, 213.4); orc1 (Danio rerio, 211.8); orc1 (Xenopus tropicalis, 219.2); Orc1 (Drosophila melanogaster, 205.3); orc-1 (Caenorhabditis elegans, 131.0); ORC1B (Arabidopsis thaliana, 193.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:135944-138703:+ | gene-YML065W_AKU4011 | rna-NM_001182424.1_AKU4011 | cds-NP_013646.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:337451-340195:- | gene-YML065W_BG1 | rna-NM_001182424.1_BG1 | cds-NP_013646.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:142086-144830:+ | gene-YML065W_Bruggeman | rna-NM_001182424.1_Bruggeman | cds-NP_013646.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:143760-146504:+ | gene-YML065W_CAT1 | rna-NM_001182424.1_CAT1 | cds-NP_013646.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:135953-138712:+ | gene-YML065W_CBS1585 | rna-NM_001182424.1_CBS1585 | cds-NP_013646.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:141854-144598:+ | gene-YML065W_CBS436 | rna-NM_001182424.1_CBS436 | cds-NP_013646.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:136661-139420:+ | gene-YML065W_CBS6412 | rna-NM_001182424.1_CBS6412 | cds-NP_013646.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:135136-137895:+ | gene-YML065W_CBS6413 | rna-NM_001182424.1_CBS6413 | cds-NP_013646.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:136932-139688:+ | gene-YML065W_CENPK1137D | rna-NM_001182424.1_CENPK1137D | cds-NP_013646.1_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:136217-138976:+ | gene-YML065W_EthanolRed | rna-NM_001182424.1_EthanolRed | cds-NP_013646.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:136724-139483:+ | gene-YML065W_FaliES1 | rna-NM_001182424.1_FaliES1 | cds-NP_013646.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000366.1:17640-20384:- | gene-YML065W_JAY291 | rna-NM_001182424.1_JAY291 | cds-NP_013646.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:140617-143358:+ | gene-YML065W_MUCL30387 | rna-NM_001182424.1_MUCL30387 | cds-NP_013646.1_MUCL30387 | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:143793-146537:+ | gene-YML065W_MUCL30388 | rna-NM_001182424.1_MUCL30388 | cds-NP_013646.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:135964-138723:+ | gene-YML065W_MUCL39482 | rna-NM_001182424.1_MUCL39482 | cds-NP_013646.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:141798-144542:+ | gene-YML065W_MUCL42920 | rna-NM_001182424.1_MUCL42920 | cds-NP_013646.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:142164-144908:+ | gene-YML065W_NCIM3186 | rna-NM_001182424.1_NCIM3186 | cds-NP_013646.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:136759-139518:+ | gene-YML065W_NCYC1407 | rna-NM_001182424.1_NCYC1407 | cds-NP_013646.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:142168-144912:+ | gene-YML065W_PE2H3 | rna-NM_001182424.1_PE2H3 | cds-NP_013646.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:142032-144776:+ | gene-YML065W_PE2H4 | rna-NM_001182424.1_PE2H4 | cds-NP_013646.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:142210-144954:+ | gene-YML065W_S288C | rna-NM_001182424.1_S288C | cds-NP_013646.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000041.1:39308-42052:- | gene-YML065W_SA1 | rna-NM_001182424.1_SA1 | cds-NP_013646.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:136016-138775:+ | gene-YML065W_ThermosaccDry | rna-NM_001182424.1_ThermosaccDry | cds-NP_013646.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:140380-143124:+ | gene-YML065W_VR1 | rna-NM_001182424.1_VR1 | cds-NP_013646.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:115553-118312:+ | gene-YML065W_ZTW1 | rna-NM_001182424.1_ZTW1 | cds-NP_013646.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:147146-149899:+ | gene-YML065W_Sparadoxus | rna-NM_001182424.1_Sparadoxus | cds-NP_013646.1_Sparadoxus | 88.7 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |