OPI1 (YHL020C)


Gene profile

Gene name: OPI1
Reference locus (S288C): YHL020C
Gene biotype: protein_coding

Description: Transcriptional repressor OPI1; Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance; null exhibits disrupted mitochondrial metabolism and low cardiolipin content, strongly correlated with overproduction of inositol; binds to phosphatidic acid

Top 10 interactors (score): SCS2 (0.998); INO2 (0.997); INO4 (0.97); INO1 (0.955); SIN3 (0.929); PAH1 (0.902); CHO1 (0.899); OPI3 (0.893); CHO2 (0.888); URA10 (0.855); URA5 (0.85); PIS1 (0.843); SWH1 (0.822); UME6 (0.79); HAC1 (0.786); ACC1 (0.78); HAP5 (0.78); ZAP1 (0.78); OSH2 (0.78); OSH3 (0.78)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:61193-62407:- gene-YHL020C_AKU4011 rna-NM_001179100.1_AKU4011 cds-NP_011843.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000180.1:14405-15607:+ gene-YHL020C_BG1 rna-NM_001179100.1_BG1 cds-NP_011843.1_BG1 98.6 99.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:67835-69037:- gene-YHL020C_Bruggeman rna-NM_001179100.1_Bruggeman cds-NP_011843.1_Bruggeman 98.6 99.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:62049-63251:- gene-YHL020C_CAT1 rna-NM_001179100.1_CAT1 cds-NP_011843.1_CAT1 98.6 99.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:61788-63002:- gene-YHL020C_CBS1585 rna-NM_001179100.1_CBS1585 cds-NP_011843.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:54303-55505:- gene-YHL020C_CBS436 rna-NM_001179100.1_CBS436 cds-NP_011843.1_CBS436 98.6 99.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:61738-62952:- gene-YHL020C_CBS6412 rna-NM_001179100.1_CBS6412 cds-NP_011843.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:61203-62381:- gene-YHL020C_CBS6413 rna-NM_001179100.1_CBS6413 cds-NP_011843.1_CBS6413 96.9 97.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:59403-60617:- gene-YHL020C_CENPK1137D rna-NM_001179100.1_CENPK1137D cds-NP_011843.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:61422-62630:- gene-YHL020C_EthanolRed rna-NM_001179100.1_EthanolRed cds-NP_011843.1_EthanolRed 99.0 99.5 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:61738-62946:- gene-YHL020C_FaliES1 rna-NM_001179100.1_FaliES1 cds-NP_011843.1_FaliES1 99.0 99.5 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000003.1:30409-31611:- gene-YHL020C_JAY291 rna-NM_001179100.1_JAY291 cds-NP_011843.1_JAY291 98.6 99.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:64824-66026:- gene-YHL020C_MUCL30387 rna-NM_001179100.1_MUCL30387 cds-NP_011843.1_MUCL30387 98.7 99.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:65520-66722:- gene-YHL020C_MUCL30388 rna-NM_001179100.1_MUCL30388 cds-NP_011843.1_MUCL30388 98.6 99.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:60779-61987:- gene-YHL020C_MUCL39482 rna-NM_001179100.1_MUCL39482 cds-NP_011843.1_MUCL39482 98.9 99.5 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:64739-65941:- gene-YHL020C_MUCL42920 rna-NM_001179100.1_MUCL42920 cds-NP_011843.1_MUCL42920 98.6 99.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:66124-67338:- gene-YHL020C_NCIM3186 rna-NM_001179100.1_NCIM3186 cds-NP_011843.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:60270-61448:- gene-YHL020C_NCYC1407 rna-NM_001179100.1_NCYC1407 cds-NP_011843.1_NCYC1407 96.9 97.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:56483-57685:- gene-YHL020C_PE2H3 rna-NM_001179100.1_PE2H3 cds-NP_011843.1_PE2H3 98.6 99.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:63924-65126:- gene-YHL020C_PE2H4 rna-NM_001179100.1_PE2H4 cds-NP_011843.1_PE2H4 98.6 99.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:66242-67456:- gene-YHL020C_S288C rna-NM_001179100.1_S288C cds-NP_011843.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:50587-51789:- gene-YHL020C_SA1 rna-NM_001179100.1_SA1 cds-NP_011843.1_SA1 98.6 99.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:62833-64041:- gene-YHL020C_ThermosaccDry rna-NM_001179100.1_ThermosaccDry cds-NP_011843.1_ThermosaccDry 99.0 99.5 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:67538-68770:- gene-YHL020C_VR1 rna-NM_001179100.1_VR1 cds-NP_011843.1_VR1 98.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:54026-55216:- gene-YHL020C_ZTW1 rna-NM_001179100.1_ZTW1 cds-NP_011843.1_ZTW1 97.5 98.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:60323-61531:- gene-YHL020C_Sparadoxus rna-NM_001179100.1_Sparadoxus cds-NP_011843.1_Sparadoxus 88.8 99.5 Verified 1 1 1 False True False False False

Additional files