Gene name: OMA1
Reference locus (S288C): YKR087C
Gene biotype: protein_coding
Description: Metalloendopeptidase of the mitochondrial inner membrane; important for adaptive responses to various homeostatic insults, preservation of normal mitochondrial function under damage-eliciting conditions, and stability of respiratory supercomplexes; involved in turnover of membrane-embedded proteins; mediates degradation of Cox1p in coa2 mutant cells; zebrafish ortholog has a role in organ development and mouse ortholog is also required for respiratory supercomplex stability
Top 10 interactors (score): YME1 (0.975); ATP23 (0.967); AFG3 (0.94); DNM1 (0.933); PCP1 (0.92); VPS1 (0.915); MGM1 (0.911); COA2 (0.888); YTA12 (0.88); PHB2 (0.84); FZO1 (0.834); MGR3 (0.824); ICP55 (0.795); PHB1 (0.779); OCT1 (0.768); SHY1 (0.766); PIM1 (0.703); YMR035W (0.692); MGR1 (0.682); STE24 (0.678)
Homologues (species, bitscore): OMA1 (Homo sapiens, 125.9); Oma1 (Mus musculus, 124.8); OMA1 (Danio rerio, 136.3); AT5G51740 (Arabidopsis thaliana, 140.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:589226-590263:- | gene-YKR087C_AKU4011 | rna-NM_001179877.1_AKU4011 | cds-NP_013013.2_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:53962-54999:+ | gene-YKR087C_BG1 | rna-NM_001179877.1_BG1 | cds-NP_013013.2_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:611804-612841:- | gene-YKR087C_Bruggeman | rna-NM_001179877.1_Bruggeman | cds-NP_013013.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:607725-608762:- | gene-YKR087C_CAT1 | rna-NM_001179877.1_CAT1 | cds-NP_013013.2_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:601713-602750:- | gene-YKR087C_CBS1585 | rna-NM_001179877.1_CBS1585 | cds-NP_013013.2_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:600098-601135:- | gene-YKR087C_CBS436 | rna-NM_001179877.1_CBS436 | cds-NP_013013.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:585001-586038:- | gene-YKR087C_CBS6412 | rna-NM_001179877.1_CBS6412 | cds-NP_013013.2_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:601531-602568:- | gene-YKR087C_CBS6413 | rna-NM_001179877.1_CBS6413 | cds-NP_013013.2_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:602850-603887:- | gene-YKR087C_CENPK1137D | rna-NM_001179877.1_CENPK1137D | cds-NP_013013.2_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:599037-600074:- | gene-YKR087C_EthanolRed | rna-NM_001179877.1_EthanolRed | cds-NP_013013.2_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:602932-603969:- | gene-YKR087C_FaliES1 | rna-NM_001179877.1_FaliES1 | cds-NP_013013.2_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000426.1:40964-42001:+ | gene-YKR087C_JAY291 | rna-NM_001179877.1_JAY291 | cds-NP_013013.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:611299-612336:- | gene-YKR087C_MUCL30387 | rna-NM_001179877.1_MUCL30387 | cds-NP_013013.2_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:605643-606680:- | gene-YKR087C_MUCL30388 | rna-NM_001179877.1_MUCL30388 | cds-NP_013013.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:600554-601591:- | gene-YKR087C_MUCL39482 | rna-NM_001179877.1_MUCL39482 | cds-NP_013013.2_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:606577-607614:- | gene-YKR087C_MUCL42920 | rna-NM_001179877.1_MUCL42920 | cds-NP_013013.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:603184-604221:- | gene-YKR087C_NCIM3186 | rna-NM_001179877.1_NCIM3186 | cds-NP_013013.2_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:600966-602003:- | gene-YKR087C_NCYC1407 | rna-NM_001179877.1_NCYC1407 | cds-NP_013013.2_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:626171-627208:- | gene-YKR087C_PE2H3 | rna-NM_001179877.1_PE2H3 | cds-NP_013013.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:610575-611612:- | gene-YKR087C_PE2H4 | rna-NM_001179877.1_PE2H4 | cds-NP_013013.2_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:603195-604232:- | gene-YKR087C_S288C | rna-NM_001179877.1_S288C | cds-NP_013013.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000029.1:77617-78654:+ | gene-YKR087C_SA1 | rna-NM_001179877.1_SA1 | cds-NP_013013.2_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:602179-603216:- | gene-YKR087C_ThermosaccDry | rna-NM_001179877.1_ThermosaccDry | cds-NP_013013.2_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:601442-602479:- | gene-YKR087C_VR1 | rna-NM_001179877.1_VR1 | cds-NP_013013.2_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:599160-600197:- | gene-YKR087C_ZTW1 | rna-NM_001179877.1_ZTW1 | cds-NP_013013.2_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:624416-625453:- | gene-YKR087C_Sparadoxus | rna-NM_001179877.1_Sparadoxus | cds-NP_013013.2_Sparadoxus | 89.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |