Gene name: OLA1
Reference locus (S288C): YBR025C
Gene biotype: protein_coding
Description: Obg-like ATPase 1; P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; null mutant displays increased translation rate and increased readthrough of premature stop codons; protein abundance increases in response to hydrogen peroxide and to DNA replication stress; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily
Top 10 interactors (score): MTG2 (0.922); VTI1 (0.9); NSE3 (0.9); YNL040W (0.897); DNM1 (0.886); ASC1 (0.815); ECM10 (0.804); TEF4 (0.803); PRE8 (0.778); FRS1 (0.761); ARP5 (0.752); TUF1 (0.738); SSC1 (0.726); GCD11 (0.713); YGR069W (0.71); RPL5 (0.704); SEN15 (0.701); YBR013C (0.692); YMR103C (0.692); MSF1 (0.659)
Homologues (species, bitscore): OLA1 (Homo sapiens, 406.8); Ola1 (Mus musculus, 406.8); ola1 (Danio rerio, 392.9); ola1 (Xenopus tropicalis, 399.4); CG1354 (Drosophila melanogaster, 379.8); tag-210 (Caenorhabditis elegans, 386.0); AT1G30580 (Arabidopsis thaliana, 394.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:273111-274295:- | gene-YBR025C_AKU4011 | rna-NM_001178373.1_AKU4011 | cds-NP_009581.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:263261-264445:- | gene-YBR025C_BG1 | rna-NM_001178373.1_BG1 | cds-NP_009581.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:273843-275027:- | gene-YBR025C_Bruggeman | rna-NM_001178373.1_Bruggeman | cds-NP_009581.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:277029-278213:- | gene-YBR025C_CAT1 | rna-NM_001178373.1_CAT1 | cds-NP_009581.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:265148-266332:- | gene-YBR025C_CBS1585 | rna-NM_001178373.1_CBS1585 | cds-NP_009581.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:273415-274599:- | gene-YBR025C_CBS436 | rna-NM_001178373.1_CBS436 | cds-NP_009581.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:363652-364836:- | gene-YBR025C_CBS6412 | rna-NM_001178373.1_CBS6412 | cds-NP_009581.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:270516-271700:- | gene-YBR025C_CBS6413 | rna-NM_001178373.1_CBS6413 | cds-NP_009581.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:284429-285613:- | gene-YBR025C_CENPK1137D | rna-NM_001178373.1_CENPK1137D | cds-NP_009581.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:400125-401309:- | gene-YBR025C_EthanolRed | rna-NM_001178373.1_EthanolRed | cds-NP_009581.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:288219-289403:- | gene-YBR025C_FaliES1 | rna-NM_001178373.1_FaliES1 | cds-NP_009581.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000048.1:8192-9376:+ | gene-YBR025C_JAY291 | rna-NM_001178373.1_JAY291 | cds-NP_009581.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:274442-275626:- | gene-YBR025C_MUCL30387 | rna-NM_001178373.1_MUCL30387 | cds-NP_009581.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:274696-275880:- | gene-YBR025C_MUCL30388 | rna-NM_001178373.1_MUCL30388 | cds-NP_009581.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:265130-266314:- | gene-YBR025C_MUCL39482 | rna-NM_001178373.1_MUCL39482 | cds-NP_009581.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:272585-273769:- | gene-YBR025C_MUCL42920 | rna-NM_001178373.1_MUCL42920 | cds-NP_009581.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:290478-291662:- | gene-YBR025C_NCIM3186 | rna-NM_001178373.1_NCIM3186 | cds-NP_009581.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:266307-267491:- | gene-YBR025C_NCYC1407 | rna-NM_001178373.1_NCYC1407 | cds-NP_009581.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:278487-279671:- | gene-YBR025C_PE2H3 | rna-NM_001178373.1_PE2H3 | cds-NP_009581.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:276155-277339:- | gene-YBR025C_PE2H4 | rna-NM_001178373.1_PE2H4 | cds-NP_009581.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:290681-291865:- | gene-YBR025C_S288C | rna-NM_001178373.1_S288C | cds-NP_009581.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000037.1:16839-18023:+ | gene-YBR025C_SA1 | rna-NM_001178373.1_SA1 | cds-NP_009581.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:287928-289112:- | gene-YBR025C_ThermosaccDry | rna-NM_001178373.1_ThermosaccDry | cds-NP_009581.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:269839-271023:- | gene-YBR025C_VR1 | rna-NM_001178373.1_VR1 | cds-NP_009581.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:263906-265090:- | gene-YBR025C_ZTW1 | rna-NM_001178373.1_ZTW1 | cds-NP_009581.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:300186-301370:- | gene-YBR025C_Sparadoxus | rna-NM_001178373.1_Sparadoxus | cds-NP_009581.1_Sparadoxus | 94.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |