OGG1 (YML060W)


Gene profile

Gene name: OGG1
Reference locus (S288C): YML060W
Gene biotype: protein_coding

Description: Nuclear and mitochondrial glycosylase/lyase; specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA, contributes to UVA resistance; Belongs to the type-1 OGG1 family

Top 10 interactors (score): NTG2 (0.981); MSH6 (0.98); NTG1 (0.978); APN2 (0.978); UNG1 (0.975); RAD27 (0.975); RAD30 (0.974); APN1 (0.967); MSH3 (0.949); MSH2 (0.944); RAD10 (0.941); CDC9 (0.932); MLH1 (0.922); RAD52 (0.921); RAD14 (0.91); CTF13 (0.9); SKP1 (0.9); CBF2 (0.9); CEP3 (0.9); YKU70 (0.835)

Homologues (species, bitscore): OGG1 (Homo sapiens, 187.2); Ogg1 (Mus musculus, 196.8); ogg1 (Danio rerio, 177.2); ogg1 (Xenopus tropicalis, 188.7); Ogg1 (Drosophila melanogaster, 157.5); OGG1 (Arabidopsis thaliana, 149.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:145614-146744:+ gene-YML060W_AKU4011 rna-NM_001182419.1_AKU4011 cds-NP_013651.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:329411-330541:- gene-YML060W_BG1 rna-NM_001182419.1_BG1 cds-NP_013651.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:151747-152877:+ gene-YML060W_Bruggeman rna-NM_001182419.1_Bruggeman cds-NP_013651.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:153414-154544:+ gene-YML060W_CAT1 rna-NM_001182419.1_CAT1 cds-NP_013651.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:145623-146753:+ gene-YML060W_CBS1585 rna-NM_001182419.1_CBS1585 cds-NP_013651.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:151508-152638:+ gene-YML060W_CBS436 rna-NM_001182419.1_CBS436 cds-NP_013651.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:146331-147461:+ gene-YML060W_CBS6412 rna-NM_001182419.1_CBS6412 cds-NP_013651.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:144806-145936:+ gene-YML060W_CBS6413 rna-NM_001182419.1_CBS6413 cds-NP_013651.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:146597-147727:+ gene-YML060W_CENPK1137D rna-NM_001182419.1_CENPK1137D cds-NP_013651.1_CENPK1137D 99.4 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:145887-147017:+ gene-YML060W_EthanolRed rna-NM_001182419.1_EthanolRed cds-NP_013651.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:146394-147524:+ gene-YML060W_FaliES1 rna-NM_001182419.1_FaliES1 cds-NP_013651.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000366.1:9600-10730:- gene-YML060W_JAY291 rna-NM_001182419.1_JAY291 cds-NP_013651.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:150269-151399:+ gene-YML060W_MUCL30387 rna-NM_001182419.1_MUCL30387 cds-NP_013651.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:153455-154585:+ gene-YML060W_MUCL30388 rna-NM_001182419.1_MUCL30388 cds-NP_013651.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:145634-146764:+ gene-YML060W_MUCL39482 rna-NM_001182419.1_MUCL39482 cds-NP_013651.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:151451-152581:+ gene-YML060W_MUCL42920 rna-NM_001182419.1_MUCL42920 cds-NP_013651.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:151825-152955:+ gene-YML060W_NCIM3186 rna-NM_001182419.1_NCIM3186 cds-NP_013651.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:146429-147559:+ gene-YML060W_NCYC1407 rna-NM_001182419.1_NCYC1407 cds-NP_013651.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:151822-152952:+ gene-YML060W_PE2H3 rna-NM_001182419.1_PE2H3 cds-NP_013651.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:151686-152816:+ gene-YML060W_PE2H4 rna-NM_001182419.1_PE2H4 cds-NP_013651.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:151871-153001:+ gene-YML060W_S288C rna-NM_001182419.1_S288C cds-NP_013651.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000041.1:31261-32391:- gene-YML060W_SA1 rna-NM_001182419.1_SA1 cds-NP_013651.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:145686-146816:+ gene-YML060W_ThermosaccDry rna-NM_001182419.1_ThermosaccDry cds-NP_013651.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:150034-151164:+ gene-YML060W_VR1 rna-NM_001182419.1_VR1 cds-NP_013651.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:125223-126353:+ gene-YML060W_ZTW1 rna-NM_001182419.1_ZTW1 cds-NP_013651.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:156817-157947:+ gene-YML060W_Sparadoxus rna-NM_001182419.1_Sparadoxus cds-NP_013651.1_Sparadoxus 89.7 100.0 Verified 1 1 1 False True False False False

Additional files