NVJ2 (YPR091C)


Gene profile

Gene name: NVJ2
Reference locus (S288C): YPR091C
Gene biotype: protein_coding

Description: Uncharacterized PH domain-containing protein YPR091C; Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ); may be involved in sterol metabolism or signaling at the NVJ; contains a synaptotagmin-like-mitochondrial-lipid binding protein (SMP) domain; binds phosphatidylinositols and other lipids in a large-scale study; may interact with ribosomes, based on co-purification experiments

Top 10 interactors (score): ARV1 (0.876); NVJ1 (0.847); NVJ3 (0.845); YBL086C (0.749); OLI1 (0.744); YMR209C (0.716); VAC8 (0.711); YDL121C (0.695); TCB1 (0.677); LNP1 (0.672); MDM1 (0.671); SCS2 (0.62); TSC13 (0.619); SWH1 (0.616); MDM34 (0.611); EMC2 (0.59); LCB2 (0.584); TCB2 (0.579); VPS13 (0.573); YNL208W (0.57)

Homologues (species, bitscore): TEX2 (Homo sapiens, 64.7); Tex2 (Mus musculus, 64.7); tex2l (Danio rerio, 79.7); tex2.1 (Xenopus tropicalis, 74.7); CG43783 (Drosophila melanogaster, 62.0); F55C12.5 (Caenorhabditis elegans, 73.6); AT1G17820 (Arabidopsis thaliana, 75.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:687837-690149:- gene-YPR091C_AKU4011 rna-NM_001184188.1_AKU4011 cds-NP_015416.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:207529-209841:+ gene-YPR091C_BG1 rna-NM_001184188.1_BG1 cds-NP_015416.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:765515-767827:- gene-YPR091C_Bruggeman rna-NM_001184188.1_Bruggeman cds-NP_015416.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:809816-812128:- gene-YPR091C_CAT1 rna-NM_001184188.1_CAT1 cds-NP_015416.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:691763-694075:- gene-YPR091C_CBS1585 rna-NM_001184188.1_CBS1585 cds-NP_015416.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:706391-708703:- gene-YPR091C_CBS436 rna-NM_001184188.1_CBS436 cds-NP_015416.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:694899-697211:- gene-YPR091C_CBS6412 rna-NM_001184188.1_CBS6412 cds-NP_015416.1_CBS6412 99.3 100.0 Unannotated 1 1 0 False False False False True
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:688720-691032:- gene-YPR091C_CBS6413 rna-NM_001184188.1_CBS6413 cds-NP_015416.1_CBS6413 99.1 100.0 Unannotated 1 1 0 False False False False True
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:716134-718446:- gene-YPR091C_CENPK1137D rna-NM_001184188.1_CENPK1137D cds-NP_015416.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:1014834-1017146:- gene-YPR091C_EthanolRed rna-NM_001184188.1_EthanolRed cds-NP_015416.1_EthanolRed 99.3 100.0 Unannotated 1 1 0 False False False False True
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:693667-695979:- gene-YPR091C_FaliES1 rna-NM_001184188.1_FaliES1 cds-NP_015416.1_FaliES1 99.3 100.0 Unannotated 1 1 0 False False False False True
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000094.1:15561-17873:- gene-YPR091C_JAY291 rna-NM_001184188.1_JAY291 cds-NP_015416.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:706774-709086:- gene-YPR091C_MUCL30387 rna-NM_001184188.1_MUCL30387 cds-NP_015416.1_MUCL30387 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:705463-707775:- gene-YPR091C_MUCL30388 rna-NM_001184188.1_MUCL30388 cds-NP_015416.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:684769-687081:- gene-YPR091C_MUCL39482 rna-NM_001184188.1_MUCL39482 cds-NP_015416.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:747615-749927:- gene-YPR091C_MUCL42920 rna-NM_001184188.1_MUCL42920 cds-NP_015416.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:716139-718451:- gene-YPR091C_NCIM3186 rna-NM_001184188.1_NCIM3186 cds-NP_015416.1_NCIM3186 95.2 100.0 Verified 1 1 0 False False False True False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:693196-695508:- gene-YPR091C_NCYC1407 rna-NM_001184188.1_NCYC1407 cds-NP_015416.1_NCYC1407 99.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:699597-701909:- gene-YPR091C_PE2H3 rna-NM_001184188.1_PE2H3 cds-NP_015416.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:699245-701557:- gene-YPR091C_PE2H4 rna-NM_001184188.1_PE2H4 cds-NP_015416.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:716156-718468:- gene-YPR091C_S288C rna-NM_001184188.1_S288C cds-NP_015416.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000028.1:14274-16586:- gene-YPR091C_SA1 rna-NM_001184188.1_SA1 cds-NP_015416.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:693442-695754:- gene-YPR091C_ThermosaccDry rna-NM_001184188.1_ThermosaccDry cds-NP_015416.1_ThermosaccDry 99.3 100.0 Unannotated 1 1 0 False False False False True
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:710085-712397:- gene-YPR091C_VR1 rna-NM_001184188.1_VR1 cds-NP_015416.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:692661-694973:- gene-YPR091C_ZTW1 rna-NM_001184188.1_ZTW1 cds-NP_015416.1_ZTW1 99.2 100.0 Unannotated 1 1 0 False False False False True
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:693410-695725:- gene-YPR091C_Sparadoxus rna-NM_001184188.1_Sparadoxus cds-NP_015416.1_Sparadoxus 89.6 100.0 Verified 1 1 1 False True False False False

Additional files