Gene name: NUT2
Reference locus (S288C): YPR168W
Gene biotype: protein_coding
Description: Subunit of the RNA polymerase II mediator complex; conserved from yeast to human; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for transcriptional activation and has a role in basal transcription; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): MED7 (0.999); ROX3 (0.999); SRB5 (0.999); CSE2 (0.999); MED8 (0.999); SRB7 (0.999); SOH1 (0.999); MED11 (0.999); MED6 (0.999); SRB4 (0.999); SRB6 (0.999); RGR1 (0.999); SSN8 (0.998); GAL11 (0.997); SRB2 (0.997); SSN3 (0.996); MED4 (0.995); MED2 (0.994); PGD1 (0.993); MED1 (0.993)
Homologues (species, bitscore): MED10 (Homo sapiens, 59.3); Med10 (Mus musculus, 59.7); med10 (Danio rerio, 58.5); med10 (Xenopus tropicalis, 58.9); AT1G26665 (Arabidopsis thaliana, 51.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:832355-832828:+ | gene-YPR168W_AKU4011 | rna-NM_001184265.1_AKU4011 | cds-NP_015494.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:64883-65356:- | gene-YPR168W_BG1 | rna-NM_001184265.1_BG1 | cds-NP_015494.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:912549-913022:+ | gene-YPR168W_Bruggeman | rna-NM_001184265.1_Bruggeman | cds-NP_015494.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:955148-955621:+ | gene-YPR168W_CAT1 | rna-NM_001184265.1_CAT1 | cds-NP_015494.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:837157-837630:+ | gene-YPR168W_CBS1585 | rna-NM_001184265.1_CBS1585 | cds-NP_015494.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:850704-851177:+ | gene-YPR168W_CBS436 | rna-NM_001184265.1_CBS436 | cds-NP_015494.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:838941-839414:+ | gene-YPR168W_CBS6412 | rna-NM_001184265.1_CBS6412 | cds-NP_015494.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:834085-834558:+ | gene-YPR168W_CBS6413 | rna-NM_001184265.1_CBS6413 | cds-NP_015494.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:878163-878636:+ | gene-YPR168W_CENPK1137D | rna-NM_001184265.1_CENPK1137D | cds-NP_015494.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1153990-1154463:+ | gene-YPR168W_EthanolRed | rna-NM_001184265.1_EthanolRed | cds-NP_015494.1_EthanolRed | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:833696-834169:+ | gene-YPR168W_FaliES1 | rna-NM_001184265.1_FaliES1 | cds-NP_015494.1_FaliES1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000081.1:21485-21958:+ | gene-YPR168W_JAY291 | rna-NM_001184265.1_JAY291 | cds-NP_015494.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:880634-881107:+ | gene-YPR168W_MUCL30387 | rna-NM_001184265.1_MUCL30387 | cds-NP_015494.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:853459-853932:+ | gene-YPR168W_MUCL30388 | rna-NM_001184265.1_MUCL30388 | cds-NP_015494.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:829357-829830:+ | gene-YPR168W_MUCL39482 | rna-NM_001184265.1_MUCL39482 | cds-NP_015494.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:893021-893494:+ | gene-YPR168W_MUCL42920 | rna-NM_001184265.1_MUCL42920 | cds-NP_015494.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:878059-878532:+ | gene-YPR168W_NCIM3186 | rna-NM_001184265.1_NCIM3186 | cds-NP_015494.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:837718-838191:+ | gene-YPR168W_NCYC1407 | rna-NM_001184265.1_NCYC1407 | cds-NP_015494.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:850009-850482:+ | gene-YPR168W_PE2H3 | rna-NM_001184265.1_PE2H3 | cds-NP_015494.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:849657-850130:+ | gene-YPR168W_PE2H4 | rna-NM_001184265.1_PE2H4 | cds-NP_015494.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:878076-878549:+ | gene-YPR168W_S288C | rna-NM_001184265.1_S288C | cds-NP_015494.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000060.1:47602-48075:- | gene-YPR168W_SA1 | rna-NM_001184265.1_SA1 | cds-NP_015494.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:833384-833857:+ | gene-YPR168W_ThermosaccDry | rna-NM_001184265.1_ThermosaccDry | cds-NP_015494.1_ThermosaccDry | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:861664-862137:+ | gene-YPR168W_VR1 | rna-NM_001184265.1_VR1 | cds-NP_015494.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:836427-836900:+ | gene-YPR168W_ZTW1 | rna-NM_001184265.1_ZTW1 | cds-NP_015494.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:838612-839085:+ | gene-YPR168W_Sparadoxus | rna-NM_001184265.1_Sparadoxus | cds-NP_015494.1_Sparadoxus | 91.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |