Gene name: NUS1
Reference locus (S288C): YDL193W
Gene biotype: protein_coding
Description: Forms dehydrodolichyl diphosphate syntase complex with RER2 or SRT1; tet-repressible mutant shows accumulation of hypoglycosylated forms of CPY, suggesting that Nus1p may be involved in protein trafficking; mutations in human homolog NUS1 have been implicated in congenital scoliosis, neurological impairment, refractory epilepsy, hearing deficit, and visual impairment; human cis-prenyltransferase complex complements yeast null mutant
Top 10 interactors (score): RER2 (0.999); SRT1 (0.996); BTS1 (0.944); DFG10 (0.935); ERG20 (0.923); COQ1 (0.922); RAM2 (0.914); RAM1 (0.909); SEC59 (0.876); ERG9 (0.864); FAA1 (0.695); LCB1 (0.669); ALG14 (0.666); CAX4 (0.645); YGR127W (0.645); FAT1 (0.643); TRM5 (0.618); ALG11 (0.603); USE1 (0.594); GSP2 (0.554)
Homologues (species, bitscore): NUS1 (Homo sapiens, 93.6); Nus1 (Mus musculus, 93.2); nus1 (Danio rerio, 81.6); nus1 (Xenopus tropicalis, 67.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:98160-99287:+ | gene-YDL193W_AKU4011 | rna-NM_001180253.1_AKU4011 | cds-NP_010088.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:449386-450513:- | gene-YDL193W_BG1 | rna-NM_001180253.1_BG1 | cds-NP_010088.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:114520-115647:+ | gene-YDL193W_Bruggeman | rna-NM_001180253.1_Bruggeman | cds-NP_010088.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:116756-117883:+ | gene-YDL193W_CAT1 | rna-NM_001180253.1_CAT1 | cds-NP_010088.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:97012-98139:+ | gene-YDL193W_CBS1585 | rna-NM_001180253.1_CBS1585 | cds-NP_010088.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:311911-313038:+ | gene-YDL193W_CBS436 | rna-NM_001180253.1_CBS436 | cds-NP_010088.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:97126-98253:+ | gene-YDL193W_CBS6412 | rna-NM_001180253.1_CBS6412 | cds-NP_010088.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:114670-115797:+ | gene-YDL193W_CBS6413 | rna-NM_001180253.1_CBS6413 | cds-NP_010088.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:113343-114470:+ | gene-YDL193W_CENPK1137D | rna-NM_001180253.1_CENPK1137D | cds-NP_010088.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:110811-111938:+ | gene-YDL193W_EthanolRed | rna-NM_001180253.1_EthanolRed | cds-NP_010088.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:115417-116544:+ | gene-YDL193W_FaliES1 | rna-NM_001180253.1_FaliES1 | cds-NP_010088.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000344.1:2711-3838:- | gene-YDL193W_JAY291 | rna-NM_001180253.1_JAY291 | cds-NP_010088.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:112787-113914:+ | gene-YDL193W_MUCL30387 | rna-NM_001180253.1_MUCL30387 | cds-NP_010088.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:102601-103728:+ | gene-YDL193W_MUCL30388 | rna-NM_001180253.1_MUCL30388 | cds-NP_010088.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:97856-98983:+ | gene-YDL193W_MUCL39482 | rna-NM_001180253.1_MUCL39482 | cds-NP_010088.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:113925-115052:+ | gene-YDL193W_MUCL42920 | rna-NM_001180253.1_MUCL42920 | cds-NP_010088.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:114595-115722:+ | gene-YDL193W_NCIM3186 | rna-NM_001180253.1_NCIM3186 | cds-NP_010088.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:97813-98940:+ | gene-YDL193W_NCYC1407 | rna-NM_001180253.1_NCYC1407 | cds-NP_010088.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:105559-106686:+ | gene-YDL193W_PE2H3 | rna-NM_001180253.1_PE2H3 | cds-NP_010088.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:105569-106696:+ | gene-YDL193W_PE2H4 | rna-NM_001180253.1_PE2H4 | cds-NP_010088.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:114672-115799:+ | gene-YDL193W_S288C | rna-NM_001180253.1_S288C | cds-NP_010088.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000090.1:29163-30290:+ | gene-YDL193W_SA1 | rna-NM_001180253.1_SA1 | cds-NP_010088.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:115176-116303:+ | gene-YDL193W_ThermosaccDry | rna-NM_001180253.1_ThermosaccDry | cds-NP_010088.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:116110-117237:+ | gene-YDL193W_VR1 | rna-NM_001180253.1_VR1 | cds-NP_010088.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:113849-114976:+ | gene-YDL193W_ZTW1 | rna-NM_001180253.1_ZTW1 | cds-NP_010088.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:117273-118400:+ | gene-YDL193W_Sparadoxus | rna-NM_001180253.1_Sparadoxus | cds-NP_010088.1_Sparadoxus | 92.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |