NUP49 (YGL172W)


Gene profile

Gene name: NUP49
Reference locus (S288C): YGL172W
Gene biotype: protein_coding

Description: FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex (NPC) permeability barrier; found in stable complex with Nic96p and two other FG-nucleoproteins (Nsp1p and Nup57p)

Top 10 interactors (score): NIC96 (0.999); NSP1 (0.999); NUP57 (0.999); NUP159 (0.995); NUP1 (0.992); NUP60 (0.991); NUP42 (0.99); NUP84 (0.985); NUP85 (0.984); NUP116 (0.984); NUP145 (0.983); ASM4 (0.983); NUP53 (0.982); NUP133 (0.981); NUP2 (0.981); NUP100 (0.978); NUP192 (0.977); GLE2 (0.974); NUP157 (0.972); KAP95 (0.971)

Homologues (species, bitscore): NUP98 (Homo sapiens, 65.5); Nup98 (Mus musculus, 67.4); nup98 (Danio rerio, 71.6); nup98 (Xenopus tropicalis, 52.0); Nup98-96 (Drosophila melanogaster, 57.8); npp-10 (Caenorhabditis elegans, 97.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:183274-184692:+ gene-YGL172W_AKU4011 rna-NM_001181037.1_AKU4011 cds-NP_011343.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:225670-227088:- gene-YGL172W_BG1 rna-NM_001181037.1_BG1 cds-NP_011343.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:185467-186885:+ gene-YGL172W_Bruggeman rna-NM_001181037.1_Bruggeman cds-NP_011343.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:181337-182755:+ gene-YGL172W_CAT1 rna-NM_001181037.1_CAT1 cds-NP_011343.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:186413-187831:+ gene-YGL172W_CBS1585 rna-NM_001181037.1_CBS1585 cds-NP_011343.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:181327-182745:+ gene-YGL172W_CBS436 rna-NM_001181037.1_CBS436 cds-NP_011343.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:172876-174294:+ gene-YGL172W_CBS6412 rna-NM_001181037.1_CBS6412 cds-NP_011343.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:180725-182143:+ gene-YGL172W_CBS6413 rna-NM_001181037.1_CBS6413 cds-NP_011343.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:180927-182345:+ gene-YGL172W_CENPK1137D rna-NM_001181037.1_CENPK1137D cds-NP_011343.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:173081-174499:+ gene-YGL172W_EthanolRed rna-NM_001181037.1_EthanolRed cds-NP_011343.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:174327-175745:+ gene-YGL172W_FaliES1 rna-NM_001181037.1_FaliES1 cds-NP_011343.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000090.1:24561-25979:+ gene-YGL172W_JAY291 rna-NM_001181037.1_JAY291 cds-NP_011343.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:182715-184133:+ gene-YGL172W_MUCL30387 rna-NM_001181037.1_MUCL30387 cds-NP_011343.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:185805-187223:+ gene-YGL172W_MUCL30388 rna-NM_001181037.1_MUCL30388 cds-NP_011343.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:183437-184855:+ gene-YGL172W_MUCL39482 rna-NM_001181037.1_MUCL39482 cds-NP_011343.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:186022-187440:+ gene-YGL172W_MUCL42920 rna-NM_001181037.1_MUCL42920 cds-NP_011343.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:180700-182118:+ gene-YGL172W_NCIM3186 rna-NM_001181037.1_NCIM3186 cds-NP_011343.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:174901-176319:+ gene-YGL172W_NCYC1407 rna-NM_001181037.1_NCYC1407 cds-NP_011343.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:176861-178279:+ gene-YGL172W_PE2H3 rna-NM_001181037.1_PE2H3 cds-NP_011343.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:176409-177827:+ gene-YGL172W_PE2H4 rna-NM_001181037.1_PE2H4 cds-NP_011343.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:180700-182118:+ gene-YGL172W_S288C rna-NM_001181037.1_S288C cds-NP_011343.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000067.1:40519-41937:+ gene-YGL172W_SA1 rna-NM_001181037.1_SA1 cds-NP_011343.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:174556-175974:+ gene-YGL172W_ThermosaccDry rna-NM_001181037.1_ThermosaccDry cds-NP_011343.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:181763-183181:+ gene-YGL172W_VR1 rna-NM_001181037.1_VR1 cds-NP_011343.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:173006-174425:+ gene-YGL172W_ZTW1 rna-NM_001181037.1_ZTW1 cds-NP_011343.1_ZTW1 99.2 100.0 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:179843-181234:+ gene-YGL172W_Sparadoxus rna-NM_001181037.1_Sparadoxus cds-NP_011343.1_Sparadoxus 88.1 97.8 Verified 1 1 1 False True False False False

Additional files