NUP159 (YIL115C)


Gene profile

Gene name: NUP159
Reference locus (S288C): YIL115C
Gene biotype: protein_coding

Description: FG-nucleoporin component of central core of the nuclear pore complex; also part of the nuclear pore complex (NPC) cytoplasmic filaments; contributes directly to nucleocytoplasmic transport; regulates ADP release from the ATP-dependent RNA helicase Dbp5p; forms a stable association with Nup82p, Gle2p and two other FG-nucleoporins (Nsp1p and Nup116p)

Top 10 interactors (score): NUP82 (0.999); NSP1 (0.999); DBP5 (0.999); GLE1 (0.999); NUP1 (0.999); NUP57 (0.999); NUP2 (0.999); NUP116 (0.999); MEX67 (0.999); NUP100 (0.998); CRM1 (0.997); GLE2 (0.996); KAP95 (0.996); NUP145 (0.996); NUP49 (0.995); NUP84 (0.995); DYN2 (0.994); ASM4 (0.989); NUP60 (0.989); NUP133 (0.988)

Homologues (species, bitscore): Nup214 (Mus musculus, 61.2); nup214 (Danio rerio, 58.9); nup214 (Xenopus tropicalis, 60.1); Nup58 (Drosophila melanogaster, 66.6); glh-2 (Caenorhabditis elegans, 60.1); AT1G10390 (Arabidopsis thaliana, 54.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:145478-150191:- gene-YIL115C_AKU4011 rna-NM_001179463.1_AKU4011 cds-NP_012151.1_AKU4011 92.5 100.0 Unannotated 1 1 0 False False False True False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:8398-13118:- gene-YIL115C_BG1 rna-NM_001179463.1_BG1 cds-NP_012151.1_BG1 92.1 100.0 Unannotated 1 1 0 False False False True False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:149891-154825:- gene-YIL115C_Bruggeman rna-NM_001179463.1_Bruggeman cds-NP_012151.1_Bruggeman 88.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:142403-146863:- gene-YIL115C_CAT1 rna-NM_001179463.1_CAT1 cds-NP_012151.1_CAT1 97.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:145735-150450:- gene-YIL115C_CBS1585 rna-NM_001179463.1_CBS1585 cds-NP_012151.1_CBS1585 92.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:136905-141365:- gene-YIL115C_CBS436 rna-NM_001179463.1_CBS436 cds-NP_012151.1_CBS436 98.0 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:143209-147825:- gene-YIL115C_CBS6412 rna-NM_001179463.1_CBS6412 cds-NP_012151.1_CBS6412 94.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:136941-141479:- gene-YIL115C_CBS6413 rna-NM_001179463.1_CBS6413 cds-NP_012151.1_CBS6413 96.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:136022-140326:- gene-YIL115C_CENPK1137D rna-NM_001179463.1_CENPK1137D cds-NP_012151.1_CENPK1137D 98.2 98.2 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:130826-135416:- gene-YIL115C_EthanolRed rna-NM_001179463.1_EthanolRed cds-NP_012151.1_EthanolRed 94.8 100.0 Unannotated 1 1 0 False False False True False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:146877-151415:- gene-YIL115C_FaliES1 rna-NM_001179463.1_FaliES1 cds-NP_012151.1_FaliES1 95.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000383.1:1-2630:+ gene-YIL115C_JAY291 rna-NM_001179463.1_JAY291 cds-NP_012151.1_JAY291 59.6 60.0 Verified 1 1 0 False False True False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:147209-151669:- gene-YIL115C_MUCL30387 rna-NM_001179463.1_MUCL30387 cds-NP_012151.1_MUCL30387 97.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:145715-150409:- gene-YIL115C_MUCL30388 rna-NM_001179463.1_MUCL30388 cds-NP_012151.1_MUCL30388 92.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:146678-151294:- gene-YIL115C_MUCL39482 rna-NM_001179463.1_MUCL39482 cds-NP_012151.1_MUCL39482 94.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:150170-154552:- gene-YIL115C_MUCL42920 rna-NM_001179463.1_MUCL42920 cds-NP_012151.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:144327-148709:- gene-YIL115C_NCIM3186 rna-NM_001179463.1_NCIM3186 cds-NP_012151.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:150722-155338:- gene-YIL115C_NCYC1407 rna-NM_001179463.1_NCYC1407 cds-NP_012151.1_NCYC1407 94.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:145212-149828:- gene-YIL115C_PE2H3 rna-NM_001179463.1_PE2H3 cds-NP_012151.1_PE2H3 94.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:139341-143864:- gene-YIL115C_PE2H4 rna-NM_001179463.1_PE2H4 cds-NP_012151.1_PE2H4 96.0 99.6 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:144327-148709:- gene-YIL115C_S288C rna-NM_001179463.1_S288C cds-NP_012151.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000058.1:34648-39108:+ gene-YIL115C_SA1 rna-NM_001179463.1_SA1 cds-NP_012151.1_SA1 97.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:145534-150072:- gene-YIL115C_ThermosaccDry rna-NM_001179463.1_ThermosaccDry cds-NP_012151.1_ThermosaccDry 95.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:142521-146981:- gene-YIL115C_VR1 rna-NM_001179463.1_VR1 cds-NP_012151.1_VR1 97.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:120399-125015:- gene-YIL115C_ZTW1 rna-NM_001179463.1_ZTW1 cds-NP_012151.1_ZTW1 94.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:138237-142829:- gene-YIL115C_Sparadoxus rna-NM_001179463.1_Sparadoxus cds-NP_012151.1_Sparadoxus 80.5 99.5 Verified 1 1 1 False True False False False

Additional files