Gene name: NUP145
Reference locus (S288C): YGL092W
Gene biotype: protein_coding
Description: Nucleoporin NUP145; Essential protein with distinct roles in two nuclear pore subcomplexes; catalyzes its own proteolytic cleavage in vivo to generate a C-terminal fragment that is a structural component of the Nup84p subcomplex (with roles in NPC biogenesis and localization of genes to the nuclear periphery), and an N-terminal fragment that is one of several FG-nucleoporins within the NPC central core directly responsible for nucleocytoplasmic transport; homologous to human NUP98
Top 10 interactors (score): NUP133 (0.999); NUP85 (0.999); NUP84 (0.999); GLE2 (0.999); SEC13 (0.999); NUP120 (0.999); SEH1 (0.999); MEX67 (0.997); NUP192 (0.997); NIC96 (0.996); NUP170 (0.996); NUP1 (0.996); NUP159 (0.996); NSP1 (0.994); NUP100 (0.993); NUP42 (0.991); NUP57 (0.991); NUP157 (0.99); NUP116 (0.99); KAP95 (0.989)
Homologues (species, bitscore): NUP98 (Homo sapiens, 156.8); Nup98 (Mus musculus, 130.6); nup98 (Danio rerio, 142.5); nup214 (Xenopus tropicalis, 59.3); Nup98-96 (Drosophila melanogaster, 147.1); npp-10 (Caenorhabditis elegans, 134.0); AT1G59660 (Arabidopsis thaliana, 98.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:340879-344865:+ | gene-YGL092W_AKU4011 | rna-NM_001180957.1_AKU4011 | cds-NP_011423.1_AKU4011 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:60552-64505:- | gene-YGL092W_BG1 | rna-NM_001180957.1_BG1 | cds-NP_011423.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:343371-347357:+ | gene-YGL092W_Bruggeman | rna-NM_001180957.1_Bruggeman | cds-NP_011423.1_Bruggeman | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:340264-344250:+ | gene-YGL092W_CAT1 | rna-NM_001180957.1_CAT1 | cds-NP_011423.1_CAT1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:344204-348190:+ | gene-YGL092W_CBS1585 | rna-NM_001180957.1_CBS1585 | cds-NP_011423.1_CBS1585 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:338488-342474:+ | gene-YGL092W_CBS436 | rna-NM_001180957.1_CBS436 | cds-NP_011423.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:328585-332571:+ | gene-YGL092W_CBS6412 | rna-NM_001180957.1_CBS6412 | cds-NP_011423.1_CBS6412 | 98.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:338510-342496:+ | gene-YGL092W_CBS6413 | rna-NM_001180957.1_CBS6413 | cds-NP_011423.1_CBS6413 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:338093-342046:+ | gene-YGL092W_CENPK1137D | rna-NM_001180957.1_CENPK1137D | cds-NP_011423.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:329964-333950:+ | gene-YGL092W_EthanolRed | rna-NM_001180957.1_EthanolRed | cds-NP_011423.1_EthanolRed | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:332525-336511:+ | gene-YGL092W_FaliES1 | rna-NM_001180957.1_FaliES1 | cds-NP_011423.1_FaliES1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000369.1:18168-22121:+ | gene-YGL092W_JAY291 | rna-NM_001180957.1_JAY291 | cds-NP_011423.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:340348-344334:+ | gene-YGL092W_MUCL30387 | rna-NM_001180957.1_MUCL30387 | cds-NP_011423.1_MUCL30387 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:343334-347320:+ | gene-YGL092W_MUCL30388 | rna-NM_001180957.1_MUCL30388 | cds-NP_011423.1_MUCL30388 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:340732-344718:+ | gene-YGL092W_MUCL39482 | rna-NM_001180957.1_MUCL39482 | cds-NP_011423.1_MUCL39482 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:345259-349245:+ | gene-YGL092W_MUCL42920 | rna-NM_001180957.1_MUCL42920 | cds-NP_011423.1_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:337906-341859:+ | gene-YGL092W_NCIM3186 | rna-NM_001180957.1_NCIM3186 | cds-NP_011423.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:332267-336253:+ | gene-YGL092W_NCYC1407 | rna-NM_001180957.1_NCYC1407 | cds-NP_011423.1_NCYC1407 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:333934-337887:+ | gene-YGL092W_PE2H3 | rna-NM_001180957.1_PE2H3 | cds-NP_011423.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:338931-342884:+ | gene-YGL092W_PE2H4 | rna-NM_001180957.1_PE2H4 | cds-NP_011423.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:337906-341859:+ | gene-YGL092W_S288C | rna-NM_001180957.1_S288C | cds-NP_011423.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000089.1:15288-19241:+ | gene-YGL092W_SA1 | rna-NM_001180957.1_SA1 | cds-NP_011423.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:332778-336764:+ | gene-YGL092W_ThermosaccDry | rna-NM_001180957.1_ThermosaccDry | cds-NP_011423.1_ThermosaccDry | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:442639-446625:+ | gene-YGL092W_VR1 | rna-NM_001180957.1_VR1 | cds-NP_011423.1_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:330132-334118:+ | gene-YGL092W_ZTW1 | rna-NM_001180957.1_ZTW1 | cds-NP_011423.1_ZTW1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:335819-339772:+ | gene-YGL092W_Sparadoxus | rna-NM_001180957.1_Sparadoxus | cds-NP_011423.1_Sparadoxus | 86.4 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |