NUP100 (YKL068W)


Gene profile

Gene name: NUP100
Reference locus (S288C): YKL068W
Gene biotype: protein_coding

Description: FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex (NPC) permeability barrier and is involved in gene tethering at the nuclear periphery; NUP100 has a paralog, NUP116, that arose from the whole genome duplication

Top 10 interactors (score): SEH1 (0.999); KAP95 (0.999); NUP84 (0.999); GLE2 (0.999); NSP1 (0.998); NUP159 (0.998); SEC13 (0.998); NUP60 (0.997); NUP1 (0.997); NUP42 (0.995); NUP57 (0.995); CRM1 (0.994); NUP2 (0.994); GLE1 (0.993); NUP192 (0.993); NUP145 (0.993); NUP116 (0.993); MEX67 (0.99); NUP133 (0.989); NUP170 (0.989)

Homologues (species, bitscore): NUP98 (Homo sapiens, 119.8); Nup98 (Mus musculus, 136.3); nup98 (Danio rerio, 125.9); nup98 (Xenopus tropicalis, 54.7); Nup98-96 (Drosophila melanogaster, 79.7); npp-10 (Caenorhabditis elegans, 130.2); AT1G59660 (Arabidopsis thaliana, 111.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:296729-299722:+ gene-YKL068W_AKU4011 rna-NM_001179634.1_AKU4011 cds-NP_012855.1_AKU4011 94.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000005.1:1559-4447:+ gene-YKL068W_BG1 rna-NM_001179634.1_BG1 cds-NP_012855.1_BG1 98.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:315778-318771:+ gene-YKL068W_Bruggeman rna-NM_001179634.1_Bruggeman cds-NP_012855.1_Bruggeman 94.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:309738-313811:+ gene-YKL068W_CAT1 rna-NM_001179634.1_CAT1 cds-NP_012855.1_CAT1 70.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:309458-312451:+ gene-YKL068W_CBS1585 rna-NM_001179634.1_CBS1585 cds-NP_012855.1_CBS1585 94.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:307603-310596:+ gene-YKL068W_CBS436 rna-NM_001179634.1_CBS436 cds-NP_012855.1_CBS436 94.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:293596-296589:+ gene-YKL068W_CBS6412 rna-NM_001179634.1_CBS6412 cds-NP_012855.1_CBS6412 94.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:309424-312417:+ gene-YKL068W_CBS6413 rna-NM_001179634.1_CBS6413 cds-NP_012855.1_CBS6413 94.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:309860-312739:+ gene-YKL068W_CENPK1137D rna-NM_001179634.1_CENPK1137D cds-NP_012855.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:307420-310413:+ gene-YKL068W_EthanolRed rna-NM_001179634.1_EthanolRed cds-NP_012855.1_EthanolRed 94.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:308233-311226:+ gene-YKL068W_FaliES1 rna-NM_001179634.1_FaliES1 cds-NP_012855.1_FaliES1 94.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000357.1:130604-133492:+ gene-YKL068W_JAY291 rna-NM_001179634.1_JAY291 cds-NP_012855.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:316678-319671:+ gene-YKL068W_MUCL30387 rna-NM_001179634.1_MUCL30387 cds-NP_012855.1_MUCL30387 94.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:311484-314580:+ gene-YKL068W_MUCL30388 rna-NM_001179634.1_MUCL30388 cds-NP_012855.1_MUCL30388 91.6 100.0 Unannotated 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:308755-311748:+ gene-YKL068W_MUCL39482 rna-NM_001179634.1_MUCL39482 cds-NP_012855.1_MUCL39482 94.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:313673-316666:+ gene-YKL068W_MUCL42920 rna-NM_001179634.1_MUCL42920 cds-NP_012855.1_MUCL42920 94.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:310188-313067:+ gene-YKL068W_NCIM3186 rna-NM_001179634.1_NCIM3186 cds-NP_012855.1_NCIM3186 98.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:308950-311943:+ gene-YKL068W_NCYC1407 rna-NM_001179634.1_NCYC1407 cds-NP_012855.1_NCYC1407 94.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:316046-318934:+ gene-YKL068W_PE2H3 rna-NM_001179634.1_PE2H3 cds-NP_012855.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:318264-321257:+ gene-YKL068W_PE2H4 rna-NM_001179634.1_PE2H4 cds-NP_012855.1_PE2H4 94.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:310199-313078:+ gene-YKL068W_S288C rna-NM_001179634.1_S288C cds-NP_012855.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:226677-229670:+ gene-YKL068W_SA1 rna-NM_001179634.1_SA1 cds-NP_012855.1_SA1 94.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:309432-312425:+ gene-YKL068W_ThermosaccDry rna-NM_001179634.1_ThermosaccDry cds-NP_012855.1_ThermosaccDry 94.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:308590-311583:+ gene-YKL068W_VR1 rna-NM_001179634.1_VR1 cds-NP_012855.1_VR1 94.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:307478-310471:+ gene-YKL068W_ZTW1 rna-NM_001179634.1_ZTW1 cds-NP_012855.1_ZTW1 94.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:326081-329095:+ gene-YKL068W_Sparadoxus rna-NM_001179634.1_Sparadoxus cds-NP_012855.1_Sparadoxus 82.3 99.8 Verified 1 1 1 False True False False False

Additional files