Gene name: NTH2
Reference locus (S288C): YBR001C
Gene biotype: protein_coding
Description: Putative neutral trehalase, required for thermotolerance; may mediate resistance to other cellular stresses; NTH2 has a paralog, NTH1, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 37 family
Top 10 interactors (score): ATH1 (0.995); TPS1 (0.993); TPS2 (0.991); TPS3 (0.988); TSL1 (0.969); NTH1 (0.966); HXK1 (0.956); GLK1 (0.954); HXK2 (0.938); EMI2 (0.938); YLR446W (0.934); HSP78 (0.915); HSP104 (0.913); PGM2 (0.901); ETR1 (0.9); MSC1 (0.895); HSP26 (0.892); SIS1 (0.889); GPH1 (0.87); PGI1 (0.824)
Homologues (species, bitscore): TREH (Homo sapiens, 118.2); Treh (Mus musculus, 112.8); treh (Danio rerio, 134.0); treh (Xenopus tropicalis, 86.7); Treh (Drosophila melanogaster, 98.2); tre-2 (Caenorhabditis elegans, 115.5); TRE1 (Arabidopsis thaliana, 114.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:227327-229669:- | gene-YBR001C_AKU4011 | rna-NM_001178349.1_AKU4011 | cds-NP_009555.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:217436-219778:- | gene-YBR001C_BG1 | rna-NM_001178349.1_BG1 | cds-NP_009555.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:228027-230369:- | gene-YBR001C_Bruggeman | rna-NM_001178349.1_Bruggeman | cds-NP_009555.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:230310-232652:- | gene-YBR001C_CAT1 | rna-NM_001178349.1_CAT1 | cds-NP_009555.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:219365-221707:- | gene-YBR001C_CBS1585 | rna-NM_001178349.1_CBS1585 | cds-NP_009555.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:227608-229950:- | gene-YBR001C_CBS436 | rna-NM_001178349.1_CBS436 | cds-NP_009555.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:317867-320209:- | gene-YBR001C_CBS6412 | rna-NM_001178349.1_CBS6412 | cds-NP_009555.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:224730-227072:- | gene-YBR001C_CBS6413 | rna-NM_001178349.1_CBS6413 | cds-NP_009555.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:238627-240969:- | gene-YBR001C_CENPK1137D | rna-NM_001178349.1_CENPK1137D | cds-NP_009555.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:354325-356667:- | gene-YBR001C_EthanolRed | rna-NM_001178349.1_EthanolRed | cds-NP_009555.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:242421-244763:- | gene-YBR001C_FaliES1 | rna-NM_001178349.1_FaliES1 | cds-NP_009555.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000048.1:52834-55176:+ | gene-YBR001C_JAY291 | rna-NM_001178349.1_JAY291 | cds-NP_009555.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:228384-230726:- | gene-YBR001C_MUCL30387 | rna-NM_001178349.1_MUCL30387 | cds-NP_009555.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:228324-230666:- | gene-YBR001C_MUCL30388 | rna-NM_001178349.1_MUCL30388 | cds-NP_009555.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:219346-221688:- | gene-YBR001C_MUCL39482 | rna-NM_001178349.1_MUCL39482 | cds-NP_009555.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:226787-229129:- | gene-YBR001C_MUCL42920 | rna-NM_001178349.1_MUCL42920 | cds-NP_009555.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:238738-241080:- | gene-YBR001C_NCIM3186 | rna-NM_001178349.1_NCIM3186 | cds-NP_009555.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:220521-222863:- | gene-YBR001C_NCYC1407 | rna-NM_001178349.1_NCYC1407 | cds-NP_009555.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:232683-235025:- | gene-YBR001C_PE2H3 | rna-NM_001178349.1_PE2H3 | cds-NP_009555.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:230340-232682:- | gene-YBR001C_PE2H4 | rna-NM_001178349.1_PE2H4 | cds-NP_009555.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:238941-241283:- | gene-YBR001C_S288C | rna-NM_001178349.1_S288C | cds-NP_009555.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000037.1:61498-63840:+ | gene-YBR001C_SA1 | rna-NM_001178349.1_SA1 | cds-NP_009555.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:242130-244472:- | gene-YBR001C_ThermosaccDry | rna-NM_001178349.1_ThermosaccDry | cds-NP_009555.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:224024-226366:- | gene-YBR001C_VR1 | rna-NM_001178349.1_VR1 | cds-NP_009555.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:218113-220455:- | gene-YBR001C_ZTW1 | rna-NM_001178349.1_ZTW1 | cds-NP_009555.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:253812-256154:- | gene-YBR001C_Sparadoxus | rna-NM_001178349.1_Sparadoxus | cds-NP_009555.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |