NTG2 (YOL043C)


Gene profile

Gene name: NTG2
Reference locus (S288C): YOL043C
Gene biotype: protein_coding

Description: Endonuclease III homolog 2; DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair, localizes to the nucleus; sumoylated; NTG2 has a paralog, NTG1, that arose from the whole genome duplication

Top 10 interactors (score): APN1 (0.996); APN2 (0.989); OGG1 (0.981); UNG1 (0.974); MLH1 (0.967); NTG1 (0.958); RAD14 (0.935); RAD27 (0.91); RAD1 (0.901); REV3 (0.9); RAD9 (0.88); RAD52 (0.869); REV1 (0.853); RAD10 (0.847); MRE11 (0.844); DUT1 (0.835); RAD3 (0.793); MET18 (0.768); CDC9 (0.76); PRI2 (0.747)

Homologues (species, bitscore): NTHL1 (Homo sapiens, 166.0); Nthl1 (Mus musculus, 173.3); nthl1 (Danio rerio, 174.5); nthl1 (Xenopus tropicalis, 160.2); CG9272 (Drosophila melanogaster, 177.2); nth-1 (Caenorhabditis elegans, 164.5); ATNTH1 (Arabidopsis thaliana, 175.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:232753-233895:- gene-YOL043C_AKU4011 rna-NM_001183297.1_AKU4011 cds-NP_014599.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:48376-49518:- gene-YOL043C_BG1 rna-NM_001183297.1_BG1 cds-NP_014599.1_BG1 98.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:235609-236751:- gene-YOL043C_Bruggeman rna-NM_001183297.1_Bruggeman cds-NP_014599.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:233466-234608:- gene-YOL043C_CAT1 rna-NM_001183297.1_CAT1 cds-NP_014599.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:227423-228565:- gene-YOL043C_CBS1585 rna-NM_001183297.1_CBS1585 cds-NP_014599.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:231703-232845:- gene-YOL043C_CBS436 rna-NM_001183297.1_CBS436 cds-NP_014599.1_CBS436 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:226787-227929:- gene-YOL043C_CBS6412 rna-NM_001183297.1_CBS6412 cds-NP_014599.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:234306-235448:- gene-YOL043C_CBS6413 rna-NM_001183297.1_CBS6413 cds-NP_014599.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:248093-249235:- gene-YOL043C_CENPK1137D rna-NM_001183297.1_CENPK1137D cds-NP_014599.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:229744-230886:- gene-YOL043C_EthanolRed rna-NM_001183297.1_EthanolRed cds-NP_014599.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:232660-233802:- gene-YOL043C_FaliES1 rna-NM_001183297.1_FaliES1 cds-NP_014599.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000018.1:32659-33801:+ gene-YOL043C_JAY291 rna-NM_001183297.1_JAY291 cds-NP_014599.1_JAY291 98.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:238632-239773:- gene-YOL043C_MUCL30387 rna-NM_001183297.1_MUCL30387 cds-NP_014599.1_MUCL30387 98.9 99.9 Unannotated 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:242982-244124:- gene-YOL043C_MUCL30388 rna-NM_001183297.1_MUCL30388 cds-NP_014599.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:234908-236050:- gene-YOL043C_MUCL39482 rna-NM_001183297.1_MUCL39482 cds-NP_014599.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:249843-250985:- gene-YOL043C_MUCL42920 rna-NM_001183297.1_MUCL42920 cds-NP_014599.1_MUCL42920 99.0 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:248281-249423:- gene-YOL043C_NCIM3186 rna-NM_001183297.1_NCIM3186 cds-NP_014599.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:241652-242794:- gene-YOL043C_NCYC1407 rna-NM_001183297.1_NCYC1407 cds-NP_014599.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:224070-225212:- gene-YOL043C_PE2H3 rna-NM_001183297.1_PE2H3 cds-NP_014599.1_PE2H3 98.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:235044-236186:- gene-YOL043C_PE2H4 rna-NM_001183297.1_PE2H4 cds-NP_014599.1_PE2H4 98.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:248392-249534:- gene-YOL043C_S288C rna-NM_001183297.1_S288C cds-NP_014599.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:216392-217534:- gene-YOL043C_SA1 rna-NM_001183297.1_SA1 cds-NP_014599.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:231231-232373:- gene-YOL043C_ThermosaccDry rna-NM_001183297.1_ThermosaccDry cds-NP_014599.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:231295-232437:- gene-YOL043C_VR1 rna-NM_001183297.1_VR1 cds-NP_014599.1_VR1 98.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000031.1:231098-232240:- gene-YOL043C_ZTW1 rna-NM_001183297.1_ZTW1 cds-NP_014599.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:239486-240628:- gene-YOL043C_Sparadoxus rna-NM_001183297.1_Sparadoxus cds-NP_014599.1_Sparadoxus 89.0 99.9 Verified 1 1 1 False True False False False

Additional files