Gene name: NSR1
Reference locus (S288C): YGR159C
Gene biotype: protein_coding
Description: Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis; binds to single stranded telomeric DNA and mRNA; methylated by Hmt1p; interaction with Top1p and nucleolar localization are negatively regulated by polyphosphorylation
Top 10 interactors (score): NOP1 (0.999); NOP56 (0.999); NIP7 (0.998); ERB1 (0.998); NOP58 (0.998); CBF5 (0.998); GAR1 (0.998); NUG1 (0.994); NHP2 (0.991); HMT1 (0.99); NOP7 (0.99); DBP2 (0.99); CIC1 (0.989); NOG1 (0.985); DBP3 (0.984); SNU13 (0.982); NOP15 (0.98); MRT4 (0.98); BFR2 (0.98); NOP12 (0.98)
Homologues (species, bitscore): NCL (Homo sapiens, 134.8); Ncl (Mus musculus, 133.7); ncl (Danio rerio, 119.0); ncl (Xenopus tropicalis, 104.4); Rox8 (Drosophila melanogaster, 94.7); tiar-2 (Caenorhabditis elegans, 109.4); NUC-L1 (Arabidopsis thaliana, 140.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:786031-787275:- | gene-YGR159C_AKU4011 | rna-NM_001181288.1_AKU4011 | cds-NP_011675.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:64177-65427:- | gene-YGR159C_BG1 | rna-NM_001181288.1_BG1 | cds-NP_011675.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:791731-792975:- | gene-YGR159C_Bruggeman | rna-NM_001181288.1_Bruggeman | cds-NP_011675.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:787798-789066:- | gene-YGR159C_CAT1 | rna-NM_001181288.1_CAT1 | cds-NP_011675.1_CAT1 | 97.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:786767-788005:- | gene-YGR159C_CBS1585 | rna-NM_001181288.1_CBS1585 | cds-NP_011675.1_CBS1585 | 99.2 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:790652-791902:- | gene-YGR159C_CBS436 | rna-NM_001181288.1_CBS436 | cds-NP_011675.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:777786-779030:- | gene-YGR159C_CBS6412 | rna-NM_001181288.1_CBS6412 | cds-NP_011675.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:783618-784862:- | gene-YGR159C_CBS6413 | rna-NM_001181288.1_CBS6413 | cds-NP_011675.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:806145-807389:- | gene-YGR159C_CENPK1137D | rna-NM_001181288.1_CENPK1137D | cds-NP_011675.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:772332-773582:- | gene-YGR159C_EthanolRed | rna-NM_001181288.1_EthanolRed | cds-NP_011675.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:776536-777786:- | gene-YGR159C_FaliES1 | rna-NM_001181288.1_FaliES1 | cds-NP_011675.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000112.1:18942-20192:- | gene-YGR159C_JAY291 | rna-NM_001181288.1_JAY291 | cds-NP_011675.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:789470-790714:- | gene-YGR159C_MUCL30387 | rna-NM_001181288.1_MUCL30387 | cds-NP_011675.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:789168-790412:- | gene-YGR159C_MUCL30388 | rna-NM_001181288.1_MUCL30388 | cds-NP_011675.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:782333-783577:- | gene-YGR159C_MUCL39482 | rna-NM_001181288.1_MUCL39482 | cds-NP_011675.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:797280-798536:- | gene-YGR159C_MUCL42920 | rna-NM_001181288.1_MUCL42920 | cds-NP_011675.1_MUCL42920 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:806412-807656:- | gene-YGR159C_NCIM3186 | rna-NM_001181288.1_NCIM3186 | cds-NP_011675.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:777436-778680:- | gene-YGR159C_NCYC1407 | rna-NM_001181288.1_NCYC1407 | cds-NP_011675.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:796645-797895:- | gene-YGR159C_PE2H3 | rna-NM_001181288.1_PE2H3 | cds-NP_011675.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:801755-803005:- | gene-YGR159C_PE2H4 | rna-NM_001181288.1_PE2H4 | cds-NP_011675.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:806412-807656:- | gene-YGR159C_S288C | rna-NM_001181288.1_S288C | cds-NP_011675.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000035.1:41562-42848:- | gene-YGR159C_SA1 | rna-NM_001181288.1_SA1 | cds-NP_011675.1_SA1 | 96.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:797043-798293:- | gene-YGR159C_ThermosaccDry | rna-NM_001181288.1_ThermosaccDry | cds-NP_011675.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:901545-903044:- | gene-YGR159C_VR1 | rna-NM_001181288.1_VR1 | cds-NP_011675.1_VR1 | 82.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:98982-100226:- | gene-YGR159C_ZTW1 | rna-NM_001181288.1_ZTW1 | cds-NP_011675.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:786564-787790:- | gene-YGR159C_Sparadoxus | rna-NM_001181288.1_Sparadoxus | cds-NP_011675.1_Sparadoxus | 92.3 | 98.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |