Gene name: NSI1
Reference locus (S288C): YDR026C
Gene biotype: protein_coding
Description: RNA polymerase I termination factor; binds to rDNA terminator element, required for efficient Pol I termination; required for rDNA silencing at NTS1; facilities association of Sir2p with NTS1, contributes to rDNA stability and cell longevity; interacts physically with Fob1p and RENT subunits, Sir2p and Net1p; may interact with ribosomes, based on co-purification experiments; Myb-like DNA-binding protein; NSI1 has a paralog, REB1, that arose from the whole genome duplication
Top 10 interactors (score): FOB1 (0.874); PRP9 (0.688); NEW1 (0.683); YEF3 (0.683); HEF3 (0.683); ATP23 (0.65); PRP46 (0.643); SIN3 (0.62); YJL206C (0.619); PRP19 (0.618); NIP100 (0.612); MUD2 (0.597); CUS1 (0.582); HSH155 (0.574); YGL242C (0.573); PRP45 (0.568); CLF1 (0.567); RPA49 (0.554); SYF1 (0.55); RPA12 (0.545)
Homologues (species, bitscore): DMTF1 (Homo sapiens, 70.1); Dmtf1 (Mus musculus, 70.1); dmtf1 (Danio rerio, 58.2); dmtf1 (Xenopus tropicalis, 59.7); AT5G41020 (Arabidopsis thaliana, 74.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:478449-480161:- | gene-YDR026C_AKU4011 | rna-NM_001180334.3_AKU4011 | cds-NP_010309.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:69614-71326:+ | gene-YDR026C_BG1 | rna-NM_001180334.3_BG1 | cds-NP_010309.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:506716-508428:- | gene-YDR026C_Bruggeman | rna-NM_001180334.3_Bruggeman | cds-NP_010309.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:491792-493504:- | gene-YDR026C_CAT1 | rna-NM_001180334.3_CAT1 | cds-NP_010309.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:475038-476750:- | gene-YDR026C_CBS1585 | rna-NM_001180334.3_CBS1585 | cds-NP_010309.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:492054-493766:- | gene-YDR026C_CBS436 | rna-NM_001180334.3_CBS436 | cds-NP_010309.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:471950-473662:- | gene-YDR026C_CBS6412 | rna-NM_001180334.3_CBS6412 | cds-NP_010309.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:494227-495939:- | gene-YDR026C_CBS6413 | rna-NM_001180334.3_CBS6413 | cds-NP_010309.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:491521-493233:- | gene-YDR026C_CENPK1137D | rna-NM_001180334.3_CENPK1137D | cds-NP_010309.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:486473-488185:- | gene-YDR026C_EthanolRed | rna-NM_001180334.3_EthanolRed | cds-NP_010309.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:492830-494542:- | gene-YDR026C_FaliES1 | rna-NM_001180334.3_FaliES1 | cds-NP_010309.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000042.1:19020-20732:+ | gene-YDR026C_JAY291 | rna-NM_001180334.3_JAY291 | cds-NP_010309.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:492300-494012:- | gene-YDR026C_MUCL30387 | rna-NM_001180334.3_MUCL30387 | cds-NP_010309.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:482761-484473:- | gene-YDR026C_MUCL30388 | rna-NM_001180334.3_MUCL30388 | cds-NP_010309.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:476406-478118:- | gene-YDR026C_MUCL39482 | rna-NM_001180334.3_MUCL39482 | cds-NP_010309.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:398090-399802:- | gene-YDR026C_MUCL42920 | rna-NM_001180334.3_MUCL42920 | cds-NP_010309.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:492479-494191:- | gene-YDR026C_NCIM3186 | rna-NM_001180334.3_NCIM3186 | cds-NP_010309.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:475839-477551:- | gene-YDR026C_NCYC1407 | rna-NM_001180334.3_NCYC1407 | cds-NP_010309.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:490960-492672:- | gene-YDR026C_PE2H3 | rna-NM_001180334.3_PE2H3 | cds-NP_010309.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:490265-491977:- | gene-YDR026C_PE2H4 | rna-NM_001180334.3_PE2H4 | cds-NP_010309.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:492556-494268:- | gene-YDR026C_S288C | rna-NM_001180334.3_S288C | cds-NP_010309.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000065.1:19725-21437:- | gene-YDR026C_SA1 | rna-NM_001180334.3_SA1 | cds-NP_010309.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:492308-494020:- | gene-YDR026C_ThermosaccDry | rna-NM_001180334.3_ThermosaccDry | cds-NP_010309.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:496899-498611:- | gene-YDR026C_VR1 | rna-NM_001180334.3_VR1 | cds-NP_010309.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:490204-491916:- | gene-YDR026C_ZTW1 | rna-NM_001180334.3_ZTW1 | cds-NP_010309.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:494679-496391:- | gene-YDR026C_Sparadoxus | rna-NM_001180334.3_Sparadoxus | cds-NP_010309.3_Sparadoxus | 86.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |