Gene name: NSG2
Reference locus (S288C): YNL156C
Gene biotype: protein_coding
Description: Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins; NSG2 has a paralog, NSG1, that arose from the whole genome duplication
Top 10 interactors (score): ERP5 (0.748); YDR090C (0.652); YFR016C (0.614); TMC1 (0.61); CTO1 (0.575); HMG2 (0.574); YMR196W (0.573); YPL247C (0.571); EMC4 (0.565); YMR295C (0.564); MLF3 (0.561); YCR023C (0.558); YET3 (0.53); YHR097C (0.526); SAY1 (0.525); RBS1 (0.489); VNX1 (0.485); COY1 (0.482); MRH1 (0.452); PRO2 (0.451)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:334781-335680:- | gene-YNL156C_AKU4011 | rna-NM_001182994.3_AKU4011 | cds-NP_014243.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:238809-239708:- | gene-YNL156C_BG1 | rna-NM_001182994.3_BG1 | cds-NP_014243.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:344847-345746:- | gene-YNL156C_Bruggeman | rna-NM_001182994.3_Bruggeman | cds-NP_014243.3_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:387775-388674:- | gene-YNL156C_CAT1 | rna-NM_001182994.3_CAT1 | cds-NP_014243.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:335432-336331:- | gene-YNL156C_CBS1585 | rna-NM_001182994.3_CBS1585 | cds-NP_014243.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:403790-404689:- | gene-YNL156C_CBS436 | rna-NM_001182994.3_CBS436 | cds-NP_014243.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:330838-331737:- | gene-YNL156C_CBS6412 | rna-NM_001182994.3_CBS6412 | cds-NP_014243.3_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:331866-332765:- | gene-YNL156C_CBS6413 | rna-NM_001182994.3_CBS6413 | cds-NP_014243.3_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:334883-335782:- | gene-YNL156C_CENPK1137D | rna-NM_001182994.3_CENPK1137D | cds-NP_014243.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:331764-332663:- | gene-YNL156C_EthanolRed | rna-NM_001182994.3_EthanolRed | cds-NP_014243.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:327677-328576:- | gene-YNL156C_FaliES1 | rna-NM_001182994.3_FaliES1 | cds-NP_014243.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000439.1:15073-15972:+ | gene-YNL156C_JAY291 | rna-NM_001182994.3_JAY291 | cds-NP_014243.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:340668-341567:- | gene-YNL156C_MUCL30387 | rna-NM_001182994.3_MUCL30387 | cds-NP_014243.3_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:375222-376121:- | gene-YNL156C_MUCL30388 | rna-NM_001182994.3_MUCL30388 | cds-NP_014243.3_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:332672-333571:- | gene-YNL156C_MUCL39482 | rna-NM_001182994.3_MUCL39482 | cds-NP_014243.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:335075-335974:- | gene-YNL156C_MUCL42920 | rna-NM_001182994.3_MUCL42920 | cds-NP_014243.3_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:341038-341937:- | gene-YNL156C_NCIM3186 | rna-NM_001182994.3_NCIM3186 | cds-NP_014243.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:334766-335665:- | gene-YNL156C_NCYC1407 | rna-NM_001182994.3_NCYC1407 | cds-NP_014243.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:331760-332659:- | gene-YNL156C_PE2H3 | rna-NM_001182994.3_PE2H3 | cds-NP_014243.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:331148-332047:- | gene-YNL156C_PE2H4 | rna-NM_001182994.3_PE2H4 | cds-NP_014243.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:341069-341968:- | gene-YNL156C_S288C | rna-NM_001182994.3_S288C | cds-NP_014243.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:71583-72482:+ | gene-YNL156C_SA1 | rna-NM_001182994.3_SA1 | cds-NP_014243.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:328534-329433:- | gene-YNL156C_ThermosaccDry | rna-NM_001182994.3_ThermosaccDry | cds-NP_014243.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:347089-347988:- | gene-YNL156C_VR1 | rna-NM_001182994.3_VR1 | cds-NP_014243.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:238356-239255:- | gene-YNL156C_ZTW1 | rna-NM_001182994.3_ZTW1 | cds-NP_014243.3_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:339184-340083:- | gene-YNL156C_Sparadoxus | rna-NM_001182994.3_Sparadoxus | cds-NP_014243.3_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |