Gene name: NSE4
Reference locus (S288C): YDL105W
Gene biotype: protein_coding
Description: Non-structural maintenance of chromosome element 4; Component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; Belongs to the NSE4 family
Top 10 interactors (score): NSE3 (0.999); MMS21 (0.999); NSE1 (0.999); SMC6 (0.999); SMC5 (0.999); KRE29 (0.989); NSE5 (0.986); SMC3 (0.986); SMT3 (0.971); SMC1 (0.941); UBC9 (0.937); IRR1 (0.921); MCD1 (0.912); MRE11 (0.875); TEP1 (0.874); MUS81 (0.826); SGS1 (0.789); SMC4 (0.775); CST9 (0.699); RTT107 (0.664)
Homologues (species, bitscore): NSMCE4A (Homo sapiens, 61.2); Nsmce4a (Mus musculus, 65.9); nsmce4a (Danio rerio, 75.1); nsmce4a (Xenopus tropicalis, 74.3); Nse4 (Drosophila melanogaster, 56.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:257010-258218:+ | gene-YDL105W_AKU4011 | rna-NM_001180164.1_AKU4011 | cds-NP_010178.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:291730-292938:- | gene-YDL105W_BG1 | rna-NM_001180164.1_BG1 | cds-NP_010178.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:274423-275631:+ | gene-YDL105W_Bruggeman | rna-NM_001180164.1_Bruggeman | cds-NP_010178.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:271164-272372:+ | gene-YDL105W_CAT1 | rna-NM_001180164.1_CAT1 | cds-NP_010178.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:255270-256478:+ | gene-YDL105W_CBS1585 | rna-NM_001180164.1_CBS1585 | cds-NP_010178.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:271933-273141:+ | gene-YDL105W_CBS436 | rna-NM_001180164.1_CBS436 | cds-NP_010178.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:253696-254904:+ | gene-YDL105W_CBS6412 | rna-NM_001180164.1_CBS6412 | cds-NP_010178.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:273431-274646:+ | gene-YDL105W_CBS6413 | rna-NM_001180164.1_CBS6413 | cds-NP_010178.1_CBS6413 | 94.9 | 98.8 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:271158-272366:+ | gene-YDL105W_CENPK1137D | rna-NM_001180164.1_CENPK1137D | cds-NP_010178.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:268036-269244:+ | gene-YDL105W_EthanolRed | rna-NM_001180164.1_EthanolRed | cds-NP_010178.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:274006-275214:+ | gene-YDL105W_FaliES1 | rna-NM_001180164.1_FaliES1 | cds-NP_010178.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000010.1:44053-45261:+ | gene-YDL105W_JAY291 | rna-NM_001180164.1_JAY291 | cds-NP_010178.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:272209-273417:+ | gene-YDL105W_MUCL30387 | rna-NM_001180164.1_MUCL30387 | cds-NP_010178.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:262968-264176:+ | gene-YDL105W_MUCL30388 | rna-NM_001180164.1_MUCL30388 | cds-NP_010178.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:256376-257584:+ | gene-YDL105W_MUCL39482 | rna-NM_001180164.1_MUCL39482 | cds-NP_010178.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:178136-179344:+ | gene-YDL105W_MUCL42920 | rna-NM_001180164.1_MUCL42920 | cds-NP_010178.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:272312-273520:+ | gene-YDL105W_NCIM3186 | rna-NM_001180164.1_NCIM3186 | cds-NP_010178.1_NCIM3186 | 87.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:256404-257612:+ | gene-YDL105W_NCYC1407 | rna-NM_001180164.1_NCYC1407 | cds-NP_010178.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:263164-264372:+ | gene-YDL105W_PE2H3 | rna-NM_001180164.1_PE2H3 | cds-NP_010178.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:263168-264376:+ | gene-YDL105W_PE2H4 | rna-NM_001180164.1_PE2H4 | cds-NP_010178.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:272389-273597:+ | gene-YDL105W_S288C | rna-NM_001180164.1_S288C | cds-NP_010178.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:161320-162528:- | gene-YDL105W_SA1 | rna-NM_001180164.1_SA1 | cds-NP_010178.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:273517-274725:+ | gene-YDL105W_ThermosaccDry | rna-NM_001180164.1_ThermosaccDry | cds-NP_010178.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:275626-276827:+ | gene-YDL105W_VR1 | rna-NM_001180164.1_VR1 | cds-NP_010178.1_VR1 | 98.7 | 99.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:271440-272648:+ | gene-YDL105W_ZTW1 | rna-NM_001180164.1_ZTW1 | cds-NP_010178.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:273577-274788:+ | gene-YDL105W_Sparadoxus | rna-NM_001180164.1_Sparadoxus | cds-NP_010178.1_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |