NRG2 (YBR066C)


Gene profile

Gene name: NRG2
Reference locus (S288C): YBR066C
Gene biotype: protein_coding

Description: Probable transcriptional regulator NRG2; Transcriptional repressor; mediates glucose repression and negatively regulates filamentous growth; activated in stochastic pulses of nuclear localization in response to low glucose

Top 10 interactors (score): SNF1 (0.905); TUP1 (0.847); FLO11 (0.75); RIM101 (0.737); TPK2 (0.723); TEC1 (0.708); PHD1 (0.696); MSS11 (0.671); GAL83 (0.666); SOK2 (0.663); ROX1 (0.639); IZH2 (0.637); KSS1 (0.635); STE12 (0.631); SFL1 (0.609); TPK1 (0.595); NRG1 (0.572); DOG2 (0.563); CYC8 (0.536); SIP1 (0.524)

Homologues (species, bitscore): KLF6 (Homo sapiens, 62.0); Klf5 (Mus musculus, 63.5); znf143a (Danio rerio, 59.7); klf5 (Xenopus tropicalis, 60.8); cbt (Drosophila melanogaster, 61.2); klf-2 (Caenorhabditis elegans, 58.2); YY1 (Arabidopsis thaliana, 51.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:352455-353117:- gene-YBR066C_AKU4011 rna-NM_001178414.1_AKU4011 cds-NP_009622.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:342712-343374:- gene-YBR066C_BG1 rna-NM_001178414.1_BG1 cds-NP_009622.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:353444-354106:- gene-YBR066C_Bruggeman rna-NM_001178414.1_Bruggeman cds-NP_009622.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:356958-357620:- gene-YBR066C_CAT1 rna-NM_001178414.1_CAT1 cds-NP_009622.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:344736-345398:- gene-YBR066C_CBS1585 rna-NM_001178414.1_CBS1585 cds-NP_009622.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:352813-353475:- gene-YBR066C_CBS436 rna-NM_001178414.1_CBS436 cds-NP_009622.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:442954-443616:- gene-YBR066C_CBS6412 rna-NM_001178414.1_CBS6412 cds-NP_009622.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:349860-350522:- gene-YBR066C_CBS6413 rna-NM_001178414.1_CBS6413 cds-NP_009622.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:363797-364459:- gene-YBR066C_CENPK1137D rna-NM_001178414.1_CENPK1137D cds-NP_009622.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:479223-479885:- gene-YBR066C_EthanolRed rna-NM_001178414.1_EthanolRed cds-NP_009622.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:368501-369163:- gene-YBR066C_FaliES1 rna-NM_001178414.1_FaliES1 cds-NP_009622.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000124.1:16438-17100:- gene-YBR066C_JAY291 rna-NM_001178414.1_JAY291 cds-NP_009622.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:354810-355472:- gene-YBR066C_MUCL30387 rna-NM_001178414.1_MUCL30387 cds-NP_009622.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:354826-355488:- gene-YBR066C_MUCL30388 rna-NM_001178414.1_MUCL30388 cds-NP_009622.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:344724-345386:- gene-YBR066C_MUCL39482 rna-NM_001178414.1_MUCL39482 cds-NP_009622.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:351945-352607:- gene-YBR066C_MUCL42920 rna-NM_001178414.1_MUCL42920 cds-NP_009622.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:369834-370496:- gene-YBR066C_NCIM3186 rna-NM_001178414.1_NCIM3186 cds-NP_009622.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:345642-346304:- gene-YBR066C_NCYC1407 rna-NM_001178414.1_NCYC1407 cds-NP_009622.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:357887-358549:- gene-YBR066C_PE2H3 rna-NM_001178414.1_PE2H3 cds-NP_009622.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:355563-356225:- gene-YBR066C_PE2H4 rna-NM_001178414.1_PE2H4 cds-NP_009622.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:370037-370699:- gene-YBR066C_S288C rna-NM_001178414.1_S288C cds-NP_009622.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000017.1:106799-107461:+ gene-YBR066C_SA1 rna-NM_001178414.1_SA1 cds-NP_009622.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:367512-368174:- gene-YBR066C_ThermosaccDry rna-NM_001178414.1_ThermosaccDry cds-NP_009622.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:349505-350167:- gene-YBR066C_VR1 rna-NM_001178414.1_VR1 cds-NP_009622.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:343198-343860:- gene-YBR066C_ZTW1 rna-NM_001178414.1_ZTW1 cds-NP_009622.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:380307-380969:- gene-YBR066C_Sparadoxus rna-NM_001178414.1_Sparadoxus cds-NP_009622.1_Sparadoxus 89.8 100.0 Verified 1 1 1 False True False False False

Additional files