Gene name: NRG1
Reference locus (S288C): YDR043C
Gene biotype: protein_coding
Description: Transcriptional regulator NRG1; Transcriptional repressor; recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response; activated in stochastic pulses of nuclear localization in response to low glucose
Top 10 interactors (score): TUP1 (0.996); RIM101 (0.982); SNF1 (0.941); CYC8 (0.895); UME6 (0.895); TEC1 (0.882); TPK2 (0.838); SOK2 (0.831); HOS2 (0.819); TPK1 (0.815); SFL1 (0.814); RIM13 (0.803); SMP1 (0.798); PHD1 (0.796); RAS1 (0.787); STE12 (0.782); CIN5 (0.779); CUP9 (0.778); CYR1 (0.776); ENA1 (0.757)
Homologues (species, bitscore): KLF12 (Homo sapiens, 64.7); Klf12 (Mus musculus, 66.6); KLF8 (Danio rerio, 66.2); klf5 (Xenopus tropicalis, 63.9); luna (Drosophila melanogaster, 61.6); klf-2 (Caenorhabditis elegans, 58.2); YY1 (Arabidopsis thaliana, 51.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:520322-521017:- | gene-YDR043C_AKU4011 | rna-NM_001180351.3_AKU4011 | cds-NP_010328.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:34183-34878:+ | gene-YDR043C_BG1 | rna-NM_001180351.3_BG1 | cds-NP_010328.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:552678-553373:- | gene-YDR043C_Bruggeman | rna-NM_001180351.3_Bruggeman | cds-NP_010328.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:535679-536374:- | gene-YDR043C_CAT1 | rna-NM_001180351.3_CAT1 | cds-NP_010328.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:511279-511974:- | gene-YDR043C_CBS1585 | rna-NM_001180351.3_CBS1585 | cds-NP_010328.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:536450-537145:- | gene-YDR043C_CBS436 | rna-NM_001180351.3_CBS436 | cds-NP_010328.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:507690-508385:- | gene-YDR043C_CBS6412 | rna-NM_001180351.3_CBS6412 | cds-NP_010328.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:536358-537053:- | gene-YDR043C_CBS6413 | rna-NM_001180351.3_CBS6413 | cds-NP_010328.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:541759-542454:- | gene-YDR043C_CENPK1137D | rna-NM_001180351.3_CENPK1137D | cds-NP_010328.3_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:522242-522937:- | gene-YDR043C_EthanolRed | rna-NM_001180351.3_EthanolRed | cds-NP_010328.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:528600-529295:- | gene-YDR043C_FaliES1 | rna-NM_001180351.3_FaliES1 | cds-NP_010328.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000246.1:25425-26120:+ | gene-YDR043C_JAY291 | rna-NM_001180351.3_JAY291 | cds-NP_010328.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:537183-537878:- | gene-YDR043C_MUCL30387 | rna-NM_001180351.3_MUCL30387 | cds-NP_010328.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:527760-528455:- | gene-YDR043C_MUCL30388 | rna-NM_001180351.3_MUCL30388 | cds-NP_010328.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:512647-513342:- | gene-YDR043C_MUCL39482 | rna-NM_001180351.3_MUCL39482 | cds-NP_010328.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:442879-443574:- | gene-YDR043C_MUCL42920 | rna-NM_001180351.3_MUCL42920 | cds-NP_010328.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:542597-543292:- | gene-YDR043C_NCIM3186 | rna-NM_001180351.3_NCIM3186 | cds-NP_010328.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:511583-512278:- | gene-YDR043C_NCYC1407 | rna-NM_001180351.3_NCYC1407 | cds-NP_010328.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:531216-531911:- | gene-YDR043C_PE2H3 | rna-NM_001180351.3_PE2H3 | cds-NP_010328.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:530521-531216:- | gene-YDR043C_PE2H4 | rna-NM_001180351.3_PE2H4 | cds-NP_010328.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:542674-543369:- | gene-YDR043C_S288C | rna-NM_001180351.3_S288C | cds-NP_010328.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000065.1:59986-60681:- | gene-YDR043C_SA1 | rna-NM_001180351.3_SA1 | cds-NP_010328.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:528077-528772:- | gene-YDR043C_ThermosaccDry | rna-NM_001180351.3_ThermosaccDry | cds-NP_010328.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:541030-541725:- | gene-YDR043C_VR1 | rna-NM_001180351.3_VR1 | cds-NP_010328.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:525937-526632:- | gene-YDR043C_ZTW1 | rna-NM_001180351.3_ZTW1 | cds-NP_010328.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:530297-530992:- | gene-YDR043C_Sparadoxus | rna-NM_001180351.3_Sparadoxus | cds-NP_010328.3_Sparadoxus | 90.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |