Gene name: NRD1
Reference locus (S288C): YNL251C
Gene biotype: protein_coding
Description: Protein NRD1; RNA-binding subunit of Nrd1 complex; complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; interacts with CTD of RNA pol II large subunit Rpo21p at phosphorylated Ser5 to direct transcription termination of non-polyadenylated transcripts; H3K4 trimethylation of transcribed regions by Set1p enhances recruitment of Nrd1p to those sites; role in regulation of mitochondrial abundance and cell size
Top 10 interactors (score): SEN1 (0.999); NAB3 (0.999); PAP2 (0.988); RPO21 (0.983); PCF11 (0.964); RRP6 (0.935); CBC2 (0.932); RTT103 (0.906); STO1 (0.869); CFT1 (0.863); RNA14 (0.848); CFT2 (0.842); RAT1 (0.836); PUB1 (0.818); AIR2 (0.807); PTA1 (0.791); YSH1 (0.783); SYC1 (0.783); FCP1 (0.763); DIS3 (0.754)
Homologues (species, bitscore): SCAF4 (Homo sapiens, 52.8); Scaf4 (Mus musculus, 53.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:166369-168096:- | gene-YNL251C_AKU4011 | rna-NM_001183089.1_AKU4011 | cds-NP_014148.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:70313-72040:- | gene-YNL251C_BG1 | rna-NM_001183089.1_BG1 | cds-NP_014148.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:176180-177907:- | gene-YNL251C_Bruggeman | rna-NM_001183089.1_Bruggeman | cds-NP_014148.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:183475-185202:- | gene-YNL251C_CAT1 | rna-NM_001183089.1_CAT1 | cds-NP_014148.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:166769-168496:- | gene-YNL251C_CBS1585 | rna-NM_001183089.1_CBS1585 | cds-NP_014148.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:161860-163587:- | gene-YNL251C_CBS436 | rna-NM_001183089.1_CBS436 | cds-NP_014148.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:163180-164907:- | gene-YNL251C_CBS6412 | rna-NM_001183089.1_CBS6412 | cds-NP_014148.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:163448-165175:- | gene-YNL251C_CBS6413 | rna-NM_001183089.1_CBS6413 | cds-NP_014148.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:166400-168127:- | gene-YNL251C_CENPK1137D | rna-NM_001183089.1_CENPK1137D | cds-NP_014148.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:164005-165732:- | gene-YNL251C_EthanolRed | rna-NM_001183089.1_EthanolRed | cds-NP_014148.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:158740-160467:- | gene-YNL251C_FaliES1 | rna-NM_001183089.1_FaliES1 | cds-NP_014148.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:69910-71637:- | gene-YNL251C_JAY291 | rna-NM_001183089.1_JAY291 | cds-NP_014148.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:171961-173688:- | gene-YNL251C_MUCL30387 | rna-NM_001183089.1_MUCL30387 | cds-NP_014148.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:170545-172272:- | gene-YNL251C_MUCL30388 | rna-NM_001183089.1_MUCL30388 | cds-NP_014148.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:164259-165986:- | gene-YNL251C_MUCL39482 | rna-NM_001183089.1_MUCL39482 | cds-NP_014148.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:166516-168243:- | gene-YNL251C_MUCL42920 | rna-NM_001183089.1_MUCL42920 | cds-NP_014148.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:172557-174284:- | gene-YNL251C_NCIM3186 | rna-NM_001183089.1_NCIM3186 | cds-NP_014148.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:166350-168077:- | gene-YNL251C_NCYC1407 | rna-NM_001183089.1_NCYC1407 | cds-NP_014148.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:163253-164980:- | gene-YNL251C_PE2H3 | rna-NM_001183089.1_PE2H3 | cds-NP_014148.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:162641-164368:- | gene-YNL251C_PE2H4 | rna-NM_001183089.1_PE2H4 | cds-NP_014148.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:172588-174315:- | gene-YNL251C_S288C | rna-NM_001183089.1_S288C | cds-NP_014148.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:77978-79705:+ | gene-YNL251C_SA1 | rna-NM_001183089.1_SA1 | cds-NP_014148.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:159596-161323:- | gene-YNL251C_ThermosaccDry | rna-NM_001183089.1_ThermosaccDry | cds-NP_014148.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:178508-180235:- | gene-YNL251C_VR1 | rna-NM_001183089.1_VR1 | cds-NP_014148.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:69941-71668:- | gene-YNL251C_ZTW1 | rna-NM_001183089.1_ZTW1 | cds-NP_014148.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:169863-171599:- | gene-YNL251C_Sparadoxus | rna-NM_001183089.1_Sparadoxus | cds-NP_014148.1_Sparadoxus | 91.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |