Gene name: NPR3
Reference locus (S288C): YHL023C
Gene biotype: protein_coding
Description: Nitrogen permease regulator 3; Subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of SEAC, a coatomer-related complex that associates dynamically with the vacuole; Npr3p may have a structural or regulatory role, supporting Iml1p function as a GAP for the Rag family GTPase Gtr1p, and leading to inhibition of TORC1 signaling in response to amino acid deprivation; SEACIT is required for non-nitrogen-starvation-induced autophagy; null mutant has meiotic defects; human NPRL3 homolog
Top 10 interactors (score): NPR2 (0.998); MTC5 (0.987); RTC1 (0.987); SEA4 (0.983); IML1 (0.982); SEH1 (0.963); SEC13 (0.953); GTR1 (0.82); GTR2 (0.76); LST7 (0.721); MEH1 (0.697); SLM4 (0.696); LST4 (0.638); YGL159W (0.606); EGO2 (0.585); NPR1 (0.575); TCO89 (0.575); YNR063W (0.568); YOR292C (0.555); WHI2 (0.545)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:54080-57520:- | gene-YHL023C_AKU4011 | rna-NM_001179103.1_AKU4011 | cds-NP_011840.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000180.1:19271-22711:+ | gene-YHL023C_BG1 | rna-NM_001179103.1_BG1 | cds-NP_011840.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:60716-64156:- | gene-YHL023C_Bruggeman | rna-NM_001179103.1_Bruggeman | cds-NP_011840.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:54945-58385:- | gene-YHL023C_CAT1 | rna-NM_001179103.1_CAT1 | cds-NP_011840.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:54675-58115:- | gene-YHL023C_CBS1585 | rna-NM_001179103.1_CBS1585 | cds-NP_011840.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:47200-50640:- | gene-YHL023C_CBS436 | rna-NM_001179103.1_CBS436 | cds-NP_011840.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:54625-58065:- | gene-YHL023C_CBS6412 | rna-NM_001179103.1_CBS6412 | cds-NP_011840.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:54090-57530:- | gene-YHL023C_CBS6413 | rna-NM_001179103.1_CBS6413 | cds-NP_011840.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:52285-55725:- | gene-YHL023C_CENPK1137D | rna-NM_001179103.1_CENPK1137D | cds-NP_011840.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:54303-57743:- | gene-YHL023C_EthanolRed | rna-NM_001179103.1_EthanolRed | cds-NP_011840.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:54619-58059:- | gene-YHL023C_FaliES1 | rna-NM_001179103.1_FaliES1 | cds-NP_011840.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000003.1:23305-26745:- | gene-YHL023C_JAY291 | rna-NM_001179103.1_JAY291 | cds-NP_011840.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:56942-60382:- | gene-YHL023C_MUCL30387 | rna-NM_001179103.1_MUCL30387 | cds-NP_011840.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:58402-61842:- | gene-YHL023C_MUCL30388 | rna-NM_001179103.1_MUCL30388 | cds-NP_011840.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:53666-57106:- | gene-YHL023C_MUCL39482 | rna-NM_001179103.1_MUCL39482 | cds-NP_011840.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:57635-61075:- | gene-YHL023C_MUCL42920 | rna-NM_001179103.1_MUCL42920 | cds-NP_011840.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:59005-62445:- | gene-YHL023C_NCIM3186 | rna-NM_001179103.1_NCIM3186 | cds-NP_011840.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:53157-56597:- | gene-YHL023C_NCYC1407 | rna-NM_001179103.1_NCYC1407 | cds-NP_011840.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:49380-52820:- | gene-YHL023C_PE2H3 | rna-NM_001179103.1_PE2H3 | cds-NP_011840.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:56821-60261:- | gene-YHL023C_PE2H4 | rna-NM_001179103.1_PE2H4 | cds-NP_011840.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:59123-62563:- | gene-YHL023C_S288C | rna-NM_001179103.1_S288C | cds-NP_011840.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:43483-46923:- | gene-YHL023C_SA1 | rna-NM_001179103.1_SA1 | cds-NP_011840.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:55714-59154:- | gene-YHL023C_ThermosaccDry | rna-NM_001179103.1_ThermosaccDry | cds-NP_011840.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:60424-63864:- | gene-YHL023C_VR1 | rna-NM_001179103.1_VR1 | cds-NP_011840.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:46913-50353:- | gene-YHL023C_ZTW1 | rna-NM_001179103.1_ZTW1 | cds-NP_011840.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:53208-56648:- | gene-YHL023C_Sparadoxus | rna-NM_001179103.1_Sparadoxus | cds-NP_011840.1_Sparadoxus | 89.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |