Gene name: NOT5
Reference locus (S288C): YPR072W
Gene biotype: protein_coding
Description: General negative regulator of transcription subunit 5; Component of the CCR4-NOT core complex, involved in mRNA decapping; involved intranscription initiation and elongation and in mRNA degradation; conserved lysine in human homolog of Not5p and Not3p is mutated in cancers
Top 10 interactors (score): NOT3 (0.999); RRP6 (0.999); MOT2 (0.999); CCR4 (0.999); CDC39 (0.999); CAF40 (0.999); CDC36 (0.999); CAF130 (0.999); POP2 (0.999); CAF16 (0.96); DHH1 (0.955); BTT1 (0.951); RPS7A (0.941); CSL4 (0.927); SKI6 (0.918); PAT1 (0.899); XRN1 (0.876); RPL17A (0.866); RPL16A (0.854); RPS22A (0.85)
Homologues (species, bitscore): CNOT3 (Homo sapiens, 164.9); Cnot3 (Mus musculus, 164.9); cnot3b (Danio rerio, 171.0); cnot3 (Xenopus tropicalis, 166.0); Not3 (Drosophila melanogaster, 169.1); ntl-3 (Caenorhabditis elegans, 115.9); AT5G18230 (Arabidopsis thaliana, 155.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:661778-663460:+ | gene-YPR072W_AKU4011 | rna-NM_001184169.1_AKU4011 | cds-NP_015397.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:234224-235906:- | gene-YPR072W_BG1 | rna-NM_001184169.1_BG1 | cds-NP_015397.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:739454-741136:+ | gene-YPR072W_Bruggeman | rna-NM_001184169.1_Bruggeman | cds-NP_015397.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:783770-785452:+ | gene-YPR072W_CAT1 | rna-NM_001184169.1_CAT1 | cds-NP_015397.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:665468-667150:+ | gene-YPR072W_CBS1585 | rna-NM_001184169.1_CBS1585 | cds-NP_015397.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:679843-681525:+ | gene-YPR072W_CBS436 | rna-NM_001184169.1_CBS436 | cds-NP_015397.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:669215-670897:+ | gene-YPR072W_CBS6412 | rna-NM_001184169.1_CBS6412 | cds-NP_015397.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:662413-664095:+ | gene-YPR072W_CBS6413 | rna-NM_001184169.1_CBS6413 | cds-NP_015397.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:690070-691752:+ | gene-YPR072W_CENPK1137D | rna-NM_001184169.1_CENPK1137D | cds-NP_015397.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:988974-990656:+ | gene-YPR072W_EthanolRed | rna-NM_001184169.1_EthanolRed | cds-NP_015397.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:667611-669293:+ | gene-YPR072W_FaliES1 | rna-NM_001184169.1_FaliES1 | cds-NP_015397.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000443.1:663-2345:+ | gene-YPR072W_JAY291 | rna-NM_001184169.1_JAY291 | cds-NP_015397.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:680714-682396:+ | gene-YPR072W_MUCL30387 | rna-NM_001184169.1_MUCL30387 | cds-NP_015397.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:679419-681101:+ | gene-YPR072W_MUCL30388 | rna-NM_001184169.1_MUCL30388 | cds-NP_015397.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:658725-660407:+ | gene-YPR072W_MUCL39482 | rna-NM_001184169.1_MUCL39482 | cds-NP_015397.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:721555-723237:+ | gene-YPR072W_MUCL42920 | rna-NM_001184169.1_MUCL42920 | cds-NP_015397.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:690090-691772:+ | gene-YPR072W_NCIM3186 | rna-NM_001184169.1_NCIM3186 | cds-NP_015397.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:666902-668584:+ | gene-YPR072W_NCYC1407 | rna-NM_001184169.1_NCYC1407 | cds-NP_015397.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:673533-675215:+ | gene-YPR072W_PE2H3 | rna-NM_001184169.1_PE2H3 | cds-NP_015397.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:673181-674863:+ | gene-YPR072W_PE2H4 | rna-NM_001184169.1_PE2H4 | cds-NP_015397.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:690107-691789:+ | gene-YPR072W_S288C | rna-NM_001184169.1_S288C | cds-NP_015397.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:8897-10579:- | gene-YPR072W_SA1 | rna-NM_001184169.1_SA1 | cds-NP_015397.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:667386-669068:+ | gene-YPR072W_ThermosaccDry | rna-NM_001184169.1_ThermosaccDry | cds-NP_015397.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:683540-685222:+ | gene-YPR072W_VR1 | rna-NM_001184169.1_VR1 | cds-NP_015397.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:666614-668296:+ | gene-YPR072W_ZTW1 | rna-NM_001184169.1_ZTW1 | cds-NP_015397.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:667345-669030:+ | gene-YPR072W_Sparadoxus | rna-NM_001184169.1_Sparadoxus | cds-NP_015397.1_Sparadoxus | 91.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |